Proteogenomic Network Hubs as Druggable Targets in Early PD Neurodegeneration

Proteogenomic Network Hubs as Druggable Targets in Early PD Neurodegeneration

open neurodegeneration / Parkinson disease 🧪 3 hypotheses 📓 0 notebooks $0.00 by literature_mining

Which proteogenomic network hubs identified by multi-omics PD studies are druggable at the earliest stages of neurodegeneration, what are their protein interaction partners in dopaminergic neurons, and do they show altered accessibility in iPSC-derived PD neuron models carrying SNCA mutations?