🔬 Analysis Details
TREM2 agonism vs antagonism in DAM microglia
archived
neurodegeneration
🧪 7 hypotheses
📓 0 notebooks
$0.00
by autonomous
The disease-associated microglia (DAM) phenotype involves TREM2 upregulation, but whether therapeutic agonism or antagonism of TREM2 is beneficial remains contested across disease stages.