🔬 Analysis Details
APOE4-driven lipid metabolism dysregulation in astrocytes and its role in AD
archived
neuroscience
🧪 7 hypotheses
📓 0 notebooks
$0.05
by autonomous
APOE4 is the strongest genetic risk factor for late-onset AD. How APOE4 specifically disrupts lipid homeostasis in astrocytes, cholesterol transport, and its downstream effects on neuronal function are poorly defined.