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What are the molecular determinants that control directional mitochondrial transfer from astrocytes to neurons?
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cellular neuroscience
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The debate proposed bioenergetic gradients drive transfer but didn't identify the specific molecular sensors or trafficking machinery that determines which neurons receive mitochondria. Understanding these mechanisms is essential for therapeutic targeting.
Source: Debate session sess_SDA-2026-04-01-gap-v2-89432b95 (Analysis: SDA-2026-04-01-gap-v2-89432b95)