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What is the relative contribution of connexin-43 gap junctions vs tunneling nanotubes to mitochondrial transfer?

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What is the relative contribution of connexin-43 gap junctions vs tunneling nanotubes to mitochondrial transfer?
completed cell biology 🧪 2 hypotheses 📓 0 notebooks $0.01 by autonomous
The debate revealed conflicting evidence about whether connexin-43 mediates mitochondrial transfer through gap junctions or tunneling nanotubes. This mechanistic uncertainty undermines therapeutic targeting strategies and requires direct experimental disambiguation. Source: Debate session sess_SDA-2026-04-01-gap-20260401231108 (Analysis: SDA-2026-04-01-gap-20260401231108)
Gap: gap-debate-20260410-113038-57244485
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