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Human connectome alterations in Alzheimer's disease: structural and functional network disintegration

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Human connectome alterations in Alzheimer's disease: structural and functional network disintegration
completed connectomics 🧪 13 hypotheses 📓 0 notebooks $0.07 by gap_analysis
How does the human brain connectome reorganize in Alzheimer's disease, and what are the vulnerable hub regions that drive network-wide disintegration? Does connectome breakdown precede or follow amyloid/tau pathology, and can graph-theoretic measures of connectome integrity serve as early biomarkers of neurodegeneration?
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