🔬 Analysis Details
Non-Neuronal Transcriptional Changes Preceding Tau Propagation as Early AD Biomarkers
open
neurodegeneration / Alzheimer disease
🧪 3 hypotheses
📓 0 notebooks
$0.00
by literature_mining
Which non-neuronal cell types (astrocytes, oligodendrocytes, pericytes) exhibit transcriptional changes in the entorhinal cortex that precede tau propagation to hippocampus and neocortex in AD, and can single-nucleus RNA-seq from cognitively normal APOE ε4 carriers identify these as pre-clinical biomarkers?