🧫 Experiment Protocol
Genetic AssociationParkinson's diseaseSox6, Anxa1mouseextracted
Knock-in Cre mouse line generated for Anxa1+ DANs; differential anatomical inputs and outputs characterized
PRIMARY OUTCOME
Identification of a vulnerable subtype of dopaminergic neurons co-expressing Sox6 and Anxa1 that shows selective vulnerability in PD.
Source: pmid_39763754