🧫 Experiment Protocol
ClinicalAlzheimer's diseasehumanextracted
NfL = neurofilament light chain; late-life biomarkers measured from 2011-2013 specimens with dementia follow-up through 2016-2019
PRIMARY OUTCOME
In late life, NfL demonstrated the strongest association with incident dementia (HR 1.92 per SD higher), exceeding associations of AD-specific biomarkers.
Source: pmid_39068543