🧫 Experiment Protocol
NeuropathologyParkinson's diseaseANXA1mouseextracted
Characterization study using MitoPark mouse model of PD; subtype identified via molecular markers
PRIMARY OUTCOME
Identified a subtype of Sox6+ Anxa1+ dopaminergic neurons that are selectively lost earlier than other DANs in MitoPark mice, with loss aligning with motor symptom development.
Source: pmid_39763754