🧫 Experiment Protocol
Gene ExpressionAlzheimer's diseasehumanextracted
Multiomics and spatial genomics used to profile cell populations
PRIMARY OUTCOME
Cell type-specific analysis identified early-phase loss of somatostatin+ inhibitory neurons and later-phase loss of excitatory neurons and Pvalb+/Vip+ inhibitory neuron subtypes across AD progression.
Source: pmid_39402379