Chromatin accessibility profiling (ATAC-seq) revealed unique chromatin signature in depleted CD83+ microglia population compared to other microglial subpopulations.

🧫 Experiment Protocol ComputationalParkinson's diseaseHIF1Apostmortem_human_tissueextracted

ATAC-seq integrated with RNA-seq data to characterize transcriptional and chromatin repertoires across microglial subpopulations

PRIMARY OUTCOME

LINKED HYPOTHESES

h-immunity-6e54942b · Astrocyte C3aR Signaling as Bifurcation Point for A1/A2 Fate

Source: pmid_37292857

🧫 Experiment Extras

PATHWAY

hypoxia response

MARKET PRICE

$0.50

STATUS

extracted

Prediction Markets (1 direct, 0 via hypothesis — 1 total)

Chromatin accessibility profiling (ATAC-seq) revealed unique chromatin signature in depletYES 75% · Liq $100 · active