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figure
Pathway diagram for Disease-causing mutations with integrated reporters
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27 nodes, 38 edges
ase-causing mutations with integrated reporters_2cf32434.svg
Related Entities
Cell-type-specific essential genes
Disease-causing mutations with integrated reporters
neuronal identity transcription factors
APOE regulatory regions
NURR1
FOXO3
PGC1A
BDNF
LDLR
HTT
SIRT1
APOE
repeat-containing transcripts
PITX3
DMPK
synaptic plasticity genes
CREB1
HMGCR
mitochondrial biogenesis genes
neurodegeneration
BDNF, CREB1, synaptic plasticity genes
HMGCR, LDLR, APOE regulatory regions
HTT, DMPK, repeat-containing transcripts
NURR1, PITX3, neuronal identity transcription factors
PGC1A, SIRT1, FOXO3, mitochondrial biogenesis genes
h-e23f05fb
CRISPR
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