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What is the complete inventory of BACE1 substrates, and how does chronic inhibition affect their function?

Open Question open Wiki: mechanisms-app-bace1-fe65-complex
What is the complete inventory of BACE1 substrates, and how does chronic inhibition affect their function?
Importance Elo
1500
Field Rank
Rank #1196 in mechanisms
Tractability
0.50
Potential Impact
0.50
Evidence Summary
Extracted from wiki page mechanisms-app-bace1-fe65-complex
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Evidence Bearing On This Question
Subcellular protein interaction role identification
partial answer for · experiment · 72%
Palmitoylation-Targeted BACE1 Trafficking Disruptors
bears on question · hypothesis · 65%
Glycine-Rich Domain Competitive Inhibition
bears on question · hypothesis · 58%
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Derived Hypotheses And Proposals
Palmitoylation-Targeted BACE1 Trafficking Disruptors
hypothesis | bears_on_question
Glycine-Rich Domain Competitive Inhibition
hypothesis | bears_on_question
Related Entities
mechanisms
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