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open question
Combination therapies**: What other targets should be combined with LRRK2 inhibition?
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Wiki: entities-lrrk2
Combination therapies**: What other targets should be combined with LRRK2 inhibition?
Importance Elo
1500
Field Rank
Rank #60 in entities
Tractability
0.50
Potential Impact
0.50
Evidence Summary
Extracted from wiki page entities-lrrk2
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Evidence Bearing On This Question
Lysosomal Calcium Channel Modulation Therapy
candidate answer
· hypothesis · 65%
Transglutaminase-2 Cross-Linking Inhibition Strategy
candidate answer
· hypothesis · 65%
PARP1 Inhibition Therapy
candidate answer
· hypothesis · 60%
TREM2-Mediated Selective Aggregate Clearance Pathway
candidate answer
· hypothesis · 55%
R-Loop Resolution Enhancement Therapy
candidate answer
· hypothesis · 55%
Low Complexity Domain Cross-Linking Inhibition
candidate answer
· hypothesis · 50%
Pairwise Tournament History
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Derived Hypotheses And Proposals
Transglutaminase-2 Cross-Linking Inhibition Strategy
hypothesis | candidate_answer
TREM2-Mediated Selective Aggregate Clearance Pathway
hypothesis | candidate_answer
R-Loop Resolution Enhancement Therapy
hypothesis | candidate_answer
PARP1 Inhibition Therapy
hypothesis | candidate_answer
Low Complexity Domain Cross-Linking Inhibition
hypothesis | candidate_answer
Lysosomal Calcium Channel Modulation Therapy
hypothesis | candidate_answer
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