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open question

What molecular mechanisms trigger the transition from the early slow-accumulation phase to the later exponential-accumulation phase of Alzheimer pathology?

Open Question open paper: 39402379
What molecular mechanisms trigger the transition from the early slow-accumulation phase to the later exponential-accumulation phase of Alzheimer pathology?
Importance Elo
1500
Field Rank
Rank #5 in neurodegeneration
Tractability
0.50
Potential Impact
0.85
Evidence Summary
Pseudoprogression analysis revealed two disease phases: early with slow increase, later with exponential increase
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Related Entities
neurodegeneration
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