APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.

📄 Paper Details

Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D'Orazio LM

Abstract

1. Nature. 2020 May;581(7806):71-76. doi: 10.1038/s41586-020-2247-3. Epub 2020 Apr 29. APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline. Montagne A(#)(1), Nation DA(#)(1)(2)(3)(4), Sagare AP(#)(1), Barisano G(#)(1), Sweeney MD(#)(1), Chakhoyan A(1), Pachicano M(1), Joe E(2)(5), Nelson AR(1), D'Orazio LM(2)(5), Buennagel DP(6), Harrington MG(6), Benzinger TLS(7)(8), Fagan AM(8)(9)(10), Ringman JM(2)(5), Schneider LS(2)(5)(11), Morris JC(9)(10), Reiman EM(12), Cas...