Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing.

📄 Paper Details

Atcha H, Jairaman A, Holt JR, Meli VS, Nagalla RR, Veerasubramanian PK, Brumm KT, Lim HE, Othy S, Cahalan MD

Nat Commun PubMed DOI

Abstract

1. Nat Commun. 2021 May 31;12(1):3256. doi: 10.1038/s41467-021-23482-5. Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing. Atcha H(1)(2), Jairaman A(3), Holt JR(3)(4), Meli VS(1)(2)(5), Nagalla RR(1)(2), Veerasubramanian PK(1)(2), Brumm KT(1)(2), Lim HE(1)(2), Othy S(3), Cahalan MD(3), Pathak MM(1)(3)(4), Liu WF(6)(7)(8). Author information: (1)Department of Biomedical Engineering, University of California Irvine, Irvine, USA. (2)The Edwards...