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paper

The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer.

📄 Paper Details
The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer.
Sohrabi E, Moslemi M, Rezaie E, Nafissi N, Khaledi M, Afkhami H, Fathi J, Zekri A
Genes & genomics PubMed DOI
Abstract

BACKGROUND: Breast cancer (BC) is a common malignancy with a high mortality rate. Malignant cell transformation is associated with metabolic changes. One group of proteins that are affected is the monocarboxylate transporters (MCTs-SLC16A). The MCTs comprise 14 members, and they play an important role in the growth, proliferation, and metabolism of cancer cells by transporting monocarboxylates such as lactate, pyruvate and thyroid hormones. OBJECTIVE: We aimed to evaluate the expression of MCT3 ...

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