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paper

C/EBPβ: A transcription factor associated with the irreversible progression of Alzheimer's disease.

📄 Paper Details
C/EBPβ: A transcription factor associated with the irreversible progression of Alzheimer's disease.
["Yao Q", "Long C", "Yi P", "Zhang G", "Wan W", "Rao X", "Ying J", "Liang W", "Hua F"]
CNS neuroscience & therapeutics PubMed DOI
Abstract

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder distinguished by a swift cognitive deterioration accompanied by distinctive pathological hallmarks such as extracellular Aβ (β-amyloid) peptides, neuronal neurofibrillary tangles (NFTs), sustained neuroinflammation, and synaptic degeneration. The elevated frequency of AD cases and its proclivity to manifest at a younger age present a pressing challenge in the quest for novel therapeutic interventions. Numerous investigations ha...

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