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paper

Tgm2-Catalyzed Covalent Cross-Linking of IκBα Drives NF-κB Nuclear Translocation to Promote SASP in Senescent Microglia.

📄 Paper Details
Tgm2-Catalyzed Covalent Cross-Linking of IκBα Drives NF-κB Nuclear Translocation to Promote SASP in Senescent Microglia.
Li Z, Wang T, Du S, Miao Z, Zhao Y, Tang Y, Meng X, Yu S, Zhang D, Jiang H
Aging Cell PubMed DOI
Abstract

1. Aging Cell. 2025 May;24(5):e14463. doi: 10.1111/acel.14463. Epub 2025 Jan 3. Tgm2-Catalyzed Covalent Cross-Linking of IκBα Drives NF-κB Nuclear Translocation to Promote SASP in Senescent Microglia. Li Z(1), Wang T(1), Du S(1), Miao Z(1), Zhao Y(1), Tang Y(1), Meng X(1), Yu S(1), Zhang D(1), Jiang H(1), Du K(1), Wei W(2), Deng H(1). Author information: (1)MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systematic Biology, School of Life Sciences, Tsinghua University, Beiji...

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