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paper

Stress granules: Guardians of cellular health and triggers of disease.

📄 Paper Details
Stress granules: Guardians of cellular health and triggers of disease.
Desai M, Gulati K, Agrawal M, Ghumra S, Sahoo PK
Neural Regen Res PubMed DOI
Abstract

Stress granules are membraneless organelles that serve as a protective cellular response to external stressors by sequestering non-translating messenger RNAs (mRNAs) and regulating protein synthesis. Stress granules formation mechanism is conserved across species, from yeast to mammals, and they play a critical role in minimizing cellular damage during stress. Composed of heterogeneous ribonucleoprotein complexes, stress granules are enriched not only in mRNAs but also in noncoding RNAs and vari...

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