A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity.

📄 Paper Details

Ana-Sosa-Batiz F, Verma SK, Shafee N, Miller R, Conner C, Hastie KM, Timis J, Maule E, Nguyen MN, Tran L

EBioMedicine PubMed DOI

Abstract

1. EBioMedicine. 2025 Mar;113:105619. doi: 10.1016/j.ebiom.2025.105619. Epub 2025 Feb 27. A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity. Ana-Sosa-Batiz F(1), Verma SK(1), Shafee N(2), Miller R(1), Conner C(3), Hastie KM(1), Timis J(1), Maule E(1), Nguyen MN(1), Tran L(1), Varghese K(1), Madany H(1), Street AE(1), Zandonatti M(1), Moi ML(4), Jarnagin K(3), Webb DR(3), Saphi...