The postnatal expression of transcripts and proteins in the corpus callosum, as well as its myelinization, is affected by the congenital absence of AQP4.

UNLABELLED: During postnatal development in mice there is a marked switch in the expression of AQP4 from white to grey matter regions. A microglial population, CD11c+, which has been shown to be involved in normal postnatal development of the corpus callosum (CC), prolongs its expression in this tissue in the absence of AQP4. Here, we investigated the correlation between the levels of AQP4 expression during the early postnatal period and the expression of marker genes related to oligodendrogenes...