The increased reliance on digital devices in our daily lives has exposed humans to intense levels of high-energy blue light. However, the harmful effects of blue light irradiation on human skin are less understood than UV irradiation. Notably, we demonstrated that blue light induces skin photoaging through a novel mechanism involving disruption of the circadian rhythm. An in vitro study using human keratinocyte cells and dermal fibroblasts was conducted. The results showed that blue light irradi...