Fig. 5Figure 6
Diverse drug loading strategies employed by viable macrophages as carriers for drug delivery. (A) Direct incubation with chemotherapeutic agents; (B) Internalization of NPs; (C) Ligand–receptor attachment; (D) Covalent coupling; (E) Other genetic modification processes, such as macrophages knocked out of SIRP- α gene by the CRISPR-Cas9 gene editing mechanism; (F) Delivery of oncolytic virus (OV).