Figure 2Figure 2
Molecular pathways involved in processes of apoptosis and pyroptosis mechanisms in cells. NLRP3—NLR family pyrin domain containing 3; NF-κB—nuclear factor kappa-light-chain enhancer of activated B cells; IL-1β—Interleukin-1 beta; IL-6—interleukin-6; IL-8—interleukin-8; TNF-α—tumor necrosis factor alpha; Bcl 2—B-cell lymphoma 2; Bax—Bcl-2-associated X protein; TGF-β—transforming growth factor-beta; Wnt—wing-less-related integration site; MAPK—mitogen-activated protein kinase. ↑ upregulation ↓ downregulation.