Fig. 5Figure 5
Assessment of cellular senescence and Ap1s1 expression. ( A ) N2a cell viability post-H₂O₂. ** p < 0.01, **** p < 0.0001, n = 6, one-way ANOVA with Tukey’s post hoc test. ( B-D ) mRNA and senescence marker analysis. *** p < 0.001, **** p < 0.0001, n = 3, unpaired two-tailed t-test. ( E-F ) Ap1s1 expression post-H₂O₂. ** p < 0.01, n = 3, unpaired two-tailed t-test. ( G-I ) N2a cell response to N2a-APP CM. *** p < 0.001, **** p < 0.0001, n = 3, unpaired two-tailed t-test. ( J-M ) Ap1s1 levels in N2a and N2a-APP cells. * p < 0.05, ** p < 0.01, n = 3, unpaired two-tailed t-test