Figure 3Figure 4
Result summary of MR and colocalization analysis on the associations between diabetes-related proteins and the risk of diabetic complications (A–C) The gray squares in (A) indicate missing data. Full name of proteins: ABO, histo-blood group ABO system transferase; ANGPTL4, angiopoietin-related protein 4; ARG1, arginase-1; ASIP, Agouti-signaling protein; BDH2, 3-hydroxybutyrate dehydrogenase type 2; BOC, brother of CDO; CTRB2, chymotrypsinogen B2; DDR1, epithelial discoidin domain-containing receptor 1; GALNT3, polypeptide N-acetylgalactosaminyltransferase 3; GCKR, glucokinase regulatory protein; HP, haptoglobin; HSPA1A, heat shock 70 kDa protein 1A; HSPA1B, heat shock 70 kDa protein 1B; HYOU1, hypoxia up-regulated protein 1; INHBB, inhibin beta B chain; KIAA1161, uncharacterized family 31 glucosidase KIAA1161; MPPED2, metallophosphoesterase MPPED2; MSRA, mitochondrial peptide methionine sulfoxide reductase; NCAN, neurocan core protein; NUCB2, nucleobindin-2; PCSK7, proprotein convertas