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Fig. 3 — A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa

Fig. 3 — A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa
Fig. 3Figure 3
Amcp induced apoptosis in pancreatic cancer cells. a Amcp induced apoptosis in BxPC-3 and SW1990 cells. Cells were treated with Amcp for 24 h before collection. Cells were then stained with Annexin V/PI and analyzed by flow cytometry. b Apoptotic cells were quantified by GraphPad Prism 5. c Cells were treated with Amcp or gemcitabine for 24 h before Western blotting assays. Three independent experiments were performed and the data were presented as the mean ± SD. * P  < 0.05, ** P  < 0.01.
PubMed: paper-8281d7c4ac82
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