FIGURE 4Figure 4
Radiobiological colony formation assay (CFA). (A) CFA for the DU145 parental (P) cells after siRNA-mediated knockdown of HSPG2, LOXL2, LAMB3, or SRPX. Cells transfected with scrambled (Scr) siRNA were used as controls. Data are mean ± SD; * p < 0.05; *** p < 0.001. (B) CFA for the DU145 radioresistant (RR) cells after siRNA-mediated knockdown of HSPG2, LOXL2, LAMB3, or SRPX. Cells transfected with scrambled siRNA (Scr siRNA) were used as controls. Data are mean ± SD; * p < 0.05; *** p < 0.001.