FIGURE 3Figure 3
Failure to restore Ca 2+ homeostasis after depolarization in YG8R CGNs. (A–C) CGNs were loaded with Fluo4-AM (A) and challenged with 30 mM KCL (B) , amplitudes were measured and showed a higher response in YG8R than Control ( C ; ∗ p < 0.05). (D,E) CGNs response to 1 μM Thapsigargin and 1mM CaCl 2 , and relative amplitudes ( ∗∗∗ p < 0.0005). Scale bar (20 μm).