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Dorsal Horn Neurons in Pain Transmission

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Dorsal Horn Neurons in Pain Transmission

Introduction

Dorsal Horn Neurons In Pain Transmission is an important cell type in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

The dorsal horn of the spinal cord is the first central processing station for nociceptive (pain) information. It receives input from peripheral sensory neurons and modulates pain signals before they ascend to the brain. Dysfunction in dorsal horn circuitry contributes to chronic pain conditions and neurodegenerative pain disorders. [@todd2010] Pain processing involves complex circuitry with multiple neuronal populations that integrate sensory information. [@basbaum2009] Dysfunction in dorsal horn circuitry contributes to chronic pain conditions and neurodegenerative pain disorders. [@woolf1999]

Overview

Multi-Taxonomy Classification

Taxonomy Database Cross-References

Morphology & Electrophysiology

  • Morphology: anterior horn motor neuron (source: Cell Ontology)
  • Morphology can be inferred from Cell Ontology classification
  • [Cell Ontology (CL:2000048)](https://www.ebi.ac.uk/ols4/ontologies/cl/classes/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_2000048)
  • [OBO Foundry (CL:2000048)](http://purl.obolibrary.org/obo/CL_2000048)
  • [Allen Brain Cell Atlas](https://portal.brain-map.org/atlases-and-data/bkp/abc-atlas)
  • [CellxGene Census](https://cellxgene.cziscience.com/)
  • [Human Cell Atlas](https://www.humancellatlas.org/)

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