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Motor Neurons in ALS and Frontotemporal Dementia

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cell547 wordssynced 2026-04-02

Motor Neurons in ALS and Frontotemporal Dementia

Introduction

<table class="infobox infobox-cell">
<tr>
<th class="infobox-header" colspan="2">Motor Neurons in ALS and Frontotemporal Dementia</th>
</tr>
<tr>
<td class="label">Taxonomy</td>
<td>ID</td>
</tr>
<tr>
<td class="label">Cell Ontology (CL)</td>
<td>[CL:0000100](https://www.ebi.ac.uk/ols4/ontologies/cl/classes/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000100)</td>
</tr>
<tr>
<td class="label">Database</td>
<td>ID</td>
</tr>
<tr>
<td class="label">Cell Ontology</td>
<td>[CL:0000100](https://www.ebi.ac.uk/ols4/ontologies/cl/classes/http%253A%252F%252Fpurl.obolibrary.org%252Fobo%252FCL_0000100)</td>
</tr>
</table>

Motor Neurons In Als And Frontotemporal Dementia is a cell type relevant to neurodegenerative disease research. This page covers its role in brain function, involvement in disease processes, and significance for therapeutic strategies.

Overview

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) exist on a spectrum of neurodegenerative disorders with shared molecular pathology. Upper and lower motor neurons degenerate in ALS, often accompanied by frontal and temporal cortical neuron loss in FTD. [@van2022]

<!-- taxonomy-enrichment --> [@brown2024]

<!-- multi-taxonomy-enrichment -->

Multi-Taxonomy Classification

Taxonomy Database Cross-References

Morphology & Electrophysiology

  • Morphology: motor neuron (source: Cell Ontology)
  • Morphology can be inferred from Cell Ontology classification

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