Dates: April 18-22, 2026
Location: McCormick Place, Chicago, Illinois, USA
Organizer: American Academy of Neurology
Website: [aanannualmeeting.com](https://www.aan.com/meetings/annual-meeting)
The plenary sessions at AAN 2026 represent the centerpiece of the conference, featuring invited presentations from world-leading researchers on the most significant advances in neurology. These sessions provide comprehensive updates across all neurological subspecialties["@aan2026program"].
Plenary Session Schedule
Sunday, April 19, 2026 — Opening Plenary
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Dates: April 18-22, 2026
Location: McCormick Place, Chicago, Illinois, USA
Organizer: American Academy of Neurology
Website: [aanannualmeeting.com](https://www.aan.com/meetings/annual-meeting)
Overview
Mermaid diagram (expand to render)
The plenary sessions at AAN 2026 represent the centerpiece of the conference, featuring invited presentations from world-leading researchers on the most significant advances in neurology. These sessions provide comprehensive updates across all neurological subspecialties["@aan2026program"].
Plenary Session Schedule
Sunday, April 19, 2026 — Opening Plenary
Theme: "The Future of Neurology: Translating Science into Practice"
The opening plenary session sets the stage for AAN 2026:
Precision Medicine in Neurology: Personalized treatment approaches
Biomarker Integration: How biomarkers are transforming clinical practice
Global Neurology: Access and equity in neurological care
AI in Neurology: Machine learning applications
Monday, April 20, 2026 — Featured Plenary
Theme: "Neurodegeneration: New Frontiers in Disease Modification"
The Monday plenary focuses on progress in neurodegenerative disease therapeutics:
Anti-Amyloid Therapies: Clinical implementation of approved antibodies
Biomarker-Guided Treatment: Precision medicine approaches
Pipeline Landscape: Therapies in clinical development
Combination Strategies: Multi-target approaches
Tuesday, April 21, 2026 — Keynote Address
Theme: "Understanding the Brain: From Mechanisms to Therapies"
The keynote address provides an integrative view of neurological disease:
Molecular Mechanisms: Protein aggregation and neurodegeneration
Neuroimmune Interactions: Inflammation and neural dysfunction
Cellular Therapies: Stem cell and gene therapy approaches
Network Neuroscience: Systems-level understanding
Wednesday, April 22, 2026 — Closing Plenary
Theme: "The Next Generation of Neurological Treatments"
The closing plenary looks forward to the future:
Gene Therapy: AAV and CRISPR approaches
RNA Therapeutics: Antisense and siRNA
Cell Replacement: iPSC and regenerative approaches
Global Health: Neurological disease worldwide
Major Scientific Topics
Neurodegeneration
Alzheimer's Disease
Approved therapies: Lecanemab and donanemab
Biomarkers: Blood-based biomarker implementation
Prevention: Primary and secondary prevention trials[@cummings2023]