Dates: October 25-29, 2025
Location: San Diego Convention Center, California, USA
Organizer: Society for Neuroscience (SfN)
Website: [sfn.org/meetings/neuroscience-2025](https://www.sfn.org/meetings/neuroscience-2025)
Overview
SfN 2025 (Neuroscience 2025) was held in San Diego, bringing together over 25,000 neuroscientists from around the world to present advances across all areas of neuroscience. The meeting is the largest annual gathering of neuroscientists, featuring thousands of presentations on basic, translational, and clinical research[@sfn2025].
Major Themes
Neurodegeneration and Alzheimer's Disease
Disease Mechanisms
[Amyloid-beta](/proteins/amyloid-beta) aggregation and toxicity mechanisms
[Tau protein](/proteins/tau) phosphorylation and spread
[Alpha-synuclein](/proteins/alpha-synuclein) pathology in Parkinson's disease
Neuroinflammation and microglial activation
Therapeutic Approaches
Disease-modifying therapies in clinical trials
Gene therapy strategies for neurodegeneration
Neuroprotection and resilience mechanisms
Regenerative medicine approaches
Parkinson's Disease
Basal ganglia circuitry and movement control
Dopamine neuron survival and replacement
Deep brain stimulation optimization
Non-motor symptoms pathophysiology
Techniques and Methods
Imaging
...
Dates: October 25-29, 2025
Location: San Diego Convention Center, California, USA
Organizer: Society for Neuroscience (SfN)
Website: [sfn.org/meetings/neuroscience-2025](https://www.sfn.org/meetings/neuroscience-2025)
Overview
SfN 2025 (Neuroscience 2025) was held in San Diego, bringing together over 25,000 neuroscientists from around the world to present advances across all areas of neuroscience. The meeting is the largest annual gathering of neuroscientists, featuring thousands of presentations on basic, translational, and clinical research[@sfn2025].
Major Themes
Neurodegeneration and Alzheimer's Disease
Disease Mechanisms
[Amyloid-beta](/proteins/amyloid-beta) aggregation and toxicity mechanisms
[Tau protein](/proteins/tau) phosphorylation and spread
[Alpha-synuclein](/proteins/alpha-synuclein) pathology in Parkinson's disease
Neuroinflammation and microglial activation
Therapeutic Approaches
Disease-modifying therapies in clinical trials
Gene therapy strategies for neurodegeneration
Neuroprotection and resilience mechanisms
Regenerative medicine approaches
Parkinson's Disease
Basal ganglia circuitry and movement control
Dopamine neuron survival and replacement
Deep brain stimulation optimization
Non-motor symptoms pathophysiology
Techniques and Methods
Imaging
Two-photon microscopy for in vivo imaging
Super-resolution microscopy for protein localization
fMRI advances and applications
Connectomics and brain mapping
Genetic and Molecular
Single-cell RNA sequencing in brain tissue
CRISPR applications in neuroscience
Optogenetics for circuit manipulation
Proteomics and metabolomics approaches
Electrophysiology
Patch-clamp recordings in vivo and in vitro
Multi-electrode arrays for large-scale recording
EEG/MEG source localization
Brain-machine interfaces
Synaptic Function and Plasticity
Synaptic transmission mechanisms
[Long-term potentiation](/mechanisms/long-term-potentiation) (LTP) and depression (LTD)
dendritic spine dynamics
Neuromodulation and behavior
Development and Regeneration
Neural development and patterning
Stem cell therapies for neurological disorders
Axon regeneration mechanisms
Neural circuits formation and refinement
Notable Sessions
Special Lectures
Presidential Special Lecture — Major advances in neuroscience
Peter Seeburg Award — Outstanding neuroscience research
Julius Axelrod Award — Pharmacological research
Symposia
"New Frontiers in Alzheimer's Disease Research"
"Alpha-Synuclein: From Basic Biology to Therapy"
"[Microglia](/cell-types/microglia-neuroinflammation) in Health and Disease"
"Neural Circuits Underlying Behavior"
Minisymposia
Over 100 minisymposia covering all neuroscience subspecialties
Focused discussions on emerging topics
New methodology presentations
Poster Sessions
Over 10,000 poster presentations
Daily poster sessions with author presentations
Networking and collaboration opportunities
Venue: San Diego Convention Center
Facilities
The San Diego Convention Center offers:
Over 500,000 square feet of exhibit space
State-of-the-art audiovisual equipment
Multiple concurrent session rooms
Dedicated poster exhibition halls
Location
The convention center is located:
Waterfront on San Diego Bay
Adjacent to downtown San Diego
Walking distance to hotels and restaurants
Easy access from San Diego International Airport
San Diego Neuroscience Community
San Diego is a major neuroscience hub:
University of California San Diego (UCSD) — Top neuroscience program
Scripps Research Institute — World-class research
Sanford Burnham Prebys Medical Discovery Institute — Neurobiology
Salk Institute for Biological Studies — Pioneering research
Related Conferences
[SfN Annual Meeting](/events/sfn-annual-meeting) — General conference page