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CNR1 Gene

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gene648 wordssynced 2026-04-02

CNR1 Gene

Introduction

Pathway Diagram

flowchart TD CNR1["CNR1 Cannabinoid Receptor 1"] CB1_signaling["Cannabinoid CB1 Receptor Signalling"] PPARG["PPARG Activation"] inflammation["Inflammation"] oxidative_stress["Oxidative Stress"] MAPK["MAPK Pathway"] IL1B["IL1B"] IL6["IL6"] TP53["TP53"] neurodegeneration["Neurodegeneration"] ALS["Amyotrophic Lateral Sclerosis"] dementia["Dementia"] neuroprotection["Neuroprotection"] CNR1 -->|"mediates"| CB1_signaling CNR1 -->|"activates"| PPARG CNR1 -->|"regulates"| inflammation CNR1 -->|"causes"| oxidative_stress CNR1 -->|"regulates"| MAPK CNR1 -->|"regulates"| IL1B CNR1 -->|"regulates"| IL6 CNR1 -->|"regulates"| TP53 inflammation -->|"promotes"| neurodegeneration oxidative_stress -->|"drives"| neurodegeneration PPARG -->|"provides"| neuroprotection neurodegeneration -->|"leads to"| ALS neurodegeneration -->|"leads to"| dementia classDef central fill:#006494,color:#e0e0e0 classDef protective fill:#1b5e20,color:#e0e0e0 classDef pathological fill:#ef5350,color:#0d0d1a classDef regulatory fill:#4a1a6b,color:#e0e0e0 classDef outcomes fill:#5d4400,color:#e0e0e0 class CNR1 central class PPARG,neuroprotection protective class inflammation,oxidative_stress,neurodegeneration pathological class CB1_signaling,MAPK,IL1B,IL6,TP53 regulatory class ALS,dementia outcomes

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