Snap23 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
<div class="infobox infobox-gene"> [@sutton1998]
| Attribute | Value | [@gerst2001] |-----------|-------| [@huang2004] | Gene Symbol | SNAP23 | [@morelli2005] | Full Name | Synaptosomal-Associated Protein 23 | | Chromosomal Location | 15q21.3 | | NCBI Gene ID | [8773](https://www.ncbi.nlm.nih.gov/gene/8773) | | Ensembl ID | ENSG00000100939 | | UniProt ID | [O95793](https://www.uniprot.org/uniprot/O95793) | | Gene Family | SNAP receptor (SNARE) | | Protein Class | Membrane fusion protein |
</div>}
Overview
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SNAP23 Gene, Synaptosomal-Associated Protein 23
Introduction
Snap23 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
<div class="infobox infobox-gene"> [@sutton1998]
| Attribute | Value | [@gerst2001] |-----------|-------| [@huang2004] | Gene Symbol | SNAP23 | [@morelli2005] | Full Name | Synaptosomal-Associated Protein 23 | | Chromosomal Location | 15q21.3 | | NCBI Gene ID | [8773](https://www.ncbi.nlm.nih.gov/gene/8773) | | Ensembl ID | ENSG00000100939 | | UniProt ID | [O95793](https://www.uniprot.org/uniprot/O95793) | | Gene Family | SNAP receptor (SNARE) | | Protein Class | Membrane fusion protein |
</div>}
Overview
Mermaid diagram (expand to render)
The SNAP23 gene encodes Synaptosomal-Associated Protein 23, a member of the SNARE (Soluble N-ethylmaleimide-sensitive factor Attachment Protein Receptor) family. SNAP23 is essential for synaptic vesicle fusion, exocytosis, and membrane trafficking in all cell types. It mediates the fusion of synaptic vesicles with the presynaptic membrane during neurotransmitter release and plays crucial roles in various cellular trafficking pathways.
PMID: 11739405(https://pubmed.ncbi.nlm.nih.gov/11739405/) - SNAP23 in exocytosis. Nat Rev Neurosci. 2001
Background
The study of Snap23 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.