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MicroRNA Dysfunction in Neurodegeneration

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mechanism1211 wordssynced 2026-04-02

MicroRNA Dysfunction in Neurodegeneration

Pathway Diagram

flowchart TD A["MicroRNA<br/>Pathway"] B["MicroRNAs<br/>Small Non-coding RNAs"] C["miRNAs<br/>Mature Forms"] D["Gene Expression<br/>Regulation"] E["ALS<br/>Motor Neuron Disease"] F["Cancer<br/>Malignancy"] G["Apoptosis<br/>Programmed Cell Death"] H["PI3K/AKT<br/>Survival Pathway"] I["Inflammation<br/>Immune Response"] J["Therapeutic<br/>Target"] K["Neurodegeneration<br/>Disease Outcome"] L["Tumor<br/>Formation"] M["Cell Death<br/>Pathways"] B -->|"regulates"| A C -->|"regulates"| A B -->|"activates"| A C -->|"expressed_in"| A A -->|"controls"| D D -->|"modulates"| G D -->|"regulates"| H H -->|"inhibits"| G G -->|"leads_to"| M A -->|"therapeutic_target"| E A -->|"therapeutic_target"| F A -->|"therapeutic_target"| I E -->|"associated_with"| K F -->|"leads_to"| L I -->|"contributes_to"| K A -->|"potential_therapy"| J G -->|"therapeutic_target"| J I -->|"therapeutic_target"| J style A fill:#006494,color:#e0e0e0 style B fill:#4a1a6b,color:#e0e0e0 style C fill:#4a1a6b,color:#e0e0e0 style D fill:#4a1a6b,color:#e0e0e0 style G fill:#ef5350,color:#0d0d1a style H fill:#1b5e20,color:#e0e0e0 style I fill:#ef5350,color:#0d0d1a style J fill:#1b5e20,color:#e0e0e0 style E fill:#5d4400,color:#e0e0e0 style F fill:#5d4400,color:#e0e0e0 style K fill:#5d4400,color:#e0e0e0 style L fill:#5d4400,color:#e0e0e0 style M fill:#ef5350,color:#0d0d1a

Overview


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