Pak1 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Pak1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Pak1 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Pak1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
<div class="infobox infobox-protein">
<table>
<tr><th colspan="2" style="background:#e8f4f8; text-align:center; font-size:1.1em;">P21 (RAC1) Activated Kinase 1</th></tr>
<tr><td><strong>Protein Name</strong></td><td>PAK1</td></tr>
<tr><td><strong>Gene</strong></td><td><a href="/genes/pak1">PAK1</a></td></tr>
<tr><td><strong>UniProt ID</strong></td><td><a href="https://www.uniprot.org/uniprot/Q13153">Q13153</a></td></tr>
<tr><td><strong>PDB Structures</strong></td><td>1F3M, 2J0I, 3Q4Z</td></tr>
<tr><td><strong>Molecular Weight</strong></td><td>65 kDa</td></tr>
<tr><td><strong>Subcellular Localization</strong></td><td>Cytoplasm, Membrane, Nucleus</td></tr>
<tr><td><strong>Protein Family</strong></td><td>PAK family</td></tr>
<tr>
<td class="label">Associated Diseases</td>
<td><a href="/wiki/als" style="color:#ef9a9a">Als</a>, <a href="/wiki/cancer" style="color:#ef9a9a">Cancer</a>, <a href="/wiki/carcinoma" style="color:#ef9a9a">Carcinoma</a>, <a href="/wiki/depression" style="color:#ef9a9a">Depression</a>, <a href="/wiki/glioblastoma" style="color:#ef9a9a">Glioblastoma</a></td>
</tr>
<tr>
<td class="label">KG Connections</td>
<td><a href="/atlas" style="color:#4fc3f7">114 edges</a></td>
</tr>
</table>
</div>
PAK1 is a protein involved in cell signaling, cytoskeletal dynamics, and p21-activated kinase activity. This protein plays a role in neurodegenerative diseases and represents a potential therapeutic target.
PAK1 is a serine/threonine kinase with distinct domains:
PAK1 regulates critical cellular processes:
PAK1 dysfunction is implicated in neurodegenerative diseases:
Pak1 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Pak1 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
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