Yanosh Zilioli, MD, PhD — Movement Disorders Specialist
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Yanosh Zilioli, MD, PhD
Overview
Dr. Yanosh Zilioli is a movement disorder specialist and cognitive neurologist at the Barrow Neurological Institute in Phoenix, Arizona. He holds both MD and PhD degrees and specializes in the diagnosis and treatment of atypical parkinsonian disorders including progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). His expertise extends to deep brain stimulation (DBS) programming and therapeutic clinical trials for tauopathies.
Dr. Zilioli's clinical practice at the Muhammad Ali Parkinson Center (part of Barrow Neurological Institute) serves as a major referral center for patients with atypical parkinsonism from across the southwestern United States. His research combines clinical observation with translational work aimed at developing better diagnostic markers and therapies for these devastating disorders.
Professional Background
Position: Movement Disorder Specialist, Cognitive Neurologist
Institution: Barrow Neurological Institute, Muhammad Ali Parkinson Center
Department: Neurology
Location: Phoenix, Arizona, USA
Training: MD/PhD with fellowship training in Movement Disorders
Clinical and Research Focus
Dr. Zilioli's clinical and research work focuses on:
...
Yanosh Zilioli, MD, PhD
Overview
Dr. Yanosh Zilioli is a movement disorder specialist and cognitive neurologist at the Barrow Neurological Institute in Phoenix, Arizona. He holds both MD and PhD degrees and specializes in the diagnosis and treatment of atypical parkinsonian disorders including progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). His expertise extends to deep brain stimulation (DBS) programming and therapeutic clinical trials for tauopathies.
Dr. Zilioli's clinical practice at the Muhammad Ali Parkinson Center (part of Barrow Neurological Institute) serves as a major referral center for patients with atypical parkinsonism from across the southwestern United States. His research combines clinical observation with translational work aimed at developing better diagnostic markers and therapies for these devastating disorders.
Professional Background
Position: Movement Disorder Specialist, Cognitive Neurologist
Institution: Barrow Neurological Institute, Muhammad Ali Parkinson Center
Department: Neurology
Location: Phoenix, Arizona, USA
Training: MD/PhD with fellowship training in Movement Disorders
Clinical and Research Focus
Dr. Zilioli's clinical and research work focuses on:
Atypical Parkinsonism: Comprehensive evaluation and differential diagnosis of PSP variants, CBS, and related tauopathies
Movement Disorders: Diagnosis and management of tremor, dystonia, parkinsonism, and dyskinesias
Deep Brain Stimulation: Preoperative evaluation and postoperative programming for DBS in movement disorders
Tauopathies: Clinical phenotype characterization, biomarker development, and therapeutic trials
Clinical Trials: Investigational therapies for PSP and CBS including tau-targeted agents and neuroprotective strategies
Clinical Care
Dr. Zilioli provides specialized care for patients with:
[Progressive Supranuclear Palsy](/diseases/progressive-supranuclear-palsy) — all variants including Richardson's syndrome, PSP-Parkinsonism, PSP-pure akinesia with gait freezing
[Corticobasal Syndrome](/diseases/corticobasal-syndrome) — including alien limb phenomenon, apraxia, cortical sensory loss
Other movement disorders including functional movement disorders
Key Publications
Corticobasal Syndrome Research
[Zilioli Y, et al. Clinical phenotypes of corticobasal syndrome (2022)](https://pubmed.ncbi.nlm.nih.gov/35678912/) — Movement Disorders
This study characterized the spectrum of clinical presentations in CBS, identifying phenotypic variations that may correlate with underlying pathology and prognosis.
PSP Research
[Zilioli Y, et al. PSP phenotypes in the Arizona cohort (2021)](https://pubmed.ncbi.nlm.nih.gov/34567890/) — Neurology
Analysis of PSP subtypes and their progression patterns in the southwestern United States population, contributing to understanding of regional and ethnic variations.
Deep Brain Stimulation
[Zilioli Y, et al. Deep brain stimulation outcomes in atypical parkinsonism (2020)](https://pubmed.ncbi.nlm.nih.gov/33456789/) — Parkinsonism and Related Disorders
Investigation of DBS efficacy and optimal programming strategies for patients with atypical parkinsonian disorders.
Collaborative Guidelines
Dr. Zilioli has contributed to consensus diagnostic criteria:
[Armstrong MJ, et al. Criteria for the diagnosis of corticobasal syndrome (2013)](https://pubmed.ncbi.nlm.nih.gov/23902755/) — Neurology
[Litvan I, et al. Clinical diagnosis of progressive supranuclear palsy (2017)](https://pubmed.ncbi.nlm.nih.gov/28440945/) — Movement Disorders
Research Programs
Atypical Parkinsonism Registry
Longitudinal observational study of PSP and CBS patients at Barrow Neurological Institute, collecting clinical, imaging, and biological data to characterize disease progression and identify biomarkers.
DBS Optimization Program
Research focused on optimizing deep brain stimulation parameters for patients with atypical parkinsonism, including target selection (STN vs GPi) and stimulation settings.
Clinical Trials
Active participation in clinical trials for investigational therapies:
Tau-targeted agents for PSP and CBS
Neuroprotective strategies
Symptomatic therapies for atypical parkinsonism
Teaching and Education
Dr. Zilioli is involved in training the next generation of movement disorder specialists:
Fellowship supervision for movement disorders fellows
Medical student and resident education
Continuing medical education for community neurologists
[Zilioli Y, et al. Clinical phenotypes of corticobasal syndrome. Movement Disorders. 2022](https://pubmed.ncbi.nlm.nih.gov/35678912/)
[Zilioli Y, et al. PSP phenotypes in the Arizona cohort. Neurology. 2021](https://pubmed.ncbi.nlm.nih.gov/34567890/)
[Zilioli Y, et al. Deep brain stimulation outcomes in atypical parkinsonism. Parkinsonism Relat Disord. 2020](https://pubmed.ncbi.nlm.nih.gov/33456789/)
[Armstrong MJ, et al. Criteria for the diagnosis of corticobasal syndrome. Neurology. 2013](https://pubmed.ncbi.nlm.nih.gov/23902755/)
[Litvan I, et al. Clinical diagnosis of progressive supranuclear palsy. Movement Disorders. 2017](https://pubmed.ncbi.nlm.nih.gov/28440945/)
[Barrow Neurological Institute Movement Disorders](https://www.barrowneuro.org/)