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plasmon resonance (pH 6.0 vs 7.4)\n• Label antibodies with fluorescent dyes (Alexa Fluor 647) for real-time tracking\n• Validate antibody integrity and binding capacity via flow cytometry\n\n**Phase 3: Real-Time Transcytosis Imaging Setup (Days 8-9)**\n• Install cranial windows in subset of mice (n=6 per genotype) under isoflurane anesthesia\n• Allow 48h recovery period with analgesics (buprenorphine 0.1mg/kg)\n• Calibrate two-photon microscopy s","replication_status":"single_study","extraction_metadata":{"backfill_at":"2026-04-16T01:00:16.910219","needs_review":true,"extraction_notes":"Backfilled from debate_extraction source (no PMID 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