{"artifact":{"id":"figure-5ded285d26a3","artifact_type":"figure","entity_ids":"[\"TREM2\", \"neurodegeneration\", \"ALOX15\", \"ALOX12\", \"HK2\", \"P2RY12\", \"C1Q\", \"C1QA\", \"CX3CR1\", \"ANXA1\", \"BMAL1\", \"CLOCK\", \"CRH\", \"ULK1\", \"LAM\", \"METABOLIC_HOMEOSTASIS\", \"NAM\", \"ALZHEIMERS\", \"APOE\", \"WAM\", \"LUNG_FIBROSIS\", \"MONOCYTE_DERIVED_MACROPHAGES\", \"ALVEOLAR_MACROPHAGES\", \"SURVIVAL_SIGNALING\", \"FIBROTIC_PHENOTYPE\", \"LIPID_MEDIATOR\", \"TISSUE_DAMAGE\", \"IMMUNE_REMODELING\", \"IMMUNE_SIGNALING\", \"METABOLIC_SYNDROME\", \"LIPIDS\", \"AL002C\", \"AMYLOID_PLAQUES\", \"NLRP3_INFLAMMASOME\", \"PARKINSONS\", \"STEATOHEPATITIS\", \"PHAGOCYTIC_ACTIVITY\", \"NEURODEGENERATIVE_DISORDERS\", \"TYROBP\", \"TREM2-mediated microglial tau clearance enhancemen\", \"Tau Propagation\", \"TMEM119\", \"GAIN\", \"MTOR\", \"JUN\"]","title":"Pathway diagram for TREM2","quality_score":0.7,"created_by":"agent","provenance_chain":null,"content_hash":"a81440e5ff274decc5ee734882ac796c4f6383b010be35ea14bcf7327a1e4e09","metadata":{"format":"svg","caption":"45 nodes, 47 edges","filepath":"data/scidex-artifacts/figures/SDA-2026-04-04-gap-tau-prop-20260402003221/pathway_TREM2_f8fcfbc9.svg","analysis_id":"SDA-2026-04-04-gap-tau-prop-20260402003221","figure_type":"pathway_diagram","_schema_version":1},"created_at":"2026-04-24T19:47:24.221043-07:00","updated_at":"2026-04-26T15:02:15.465644-07:00","version_number":7,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-24T19:47:24.221043-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":null,"contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"2f167ef9-71c1-49fb-b224-87291d8b2289","artifact_dir":"data/scidex-artifacts/2f/2f167ef9-71c1-49fb-b224-87291d8b2289","primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":"2026-04-28T19:51:43.570675-07:00","hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"agent"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"analysis-SDA-2026-04-04-gap-tau-prop-20260402003221","link_type":"derives_from","strength":1.0,"evidence":"metadata.analysis_id = SDA-2026-04-04-gap-tau-prop-20260402003221"},{"target_artifact_id":"wiki-TREM2","link_type":"mentions","strength":0.8,"evidence":"entity_ids contains 'TREM2', wiki artifact exists"},{"target_artifact_id":"wiki-neurodegeneration","link_type":"mentions","strength":0.8,"evidence":"entity_ids contains 'neurodegeneration', wiki artifact exists"}],"incoming_links":[],"current_artifact_id":"figure-5ded285d26a3","is_canonical":true,"supersede_chain":["figure-5ded285d26a3"]}