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wiki/cell-types-habenular-commissure-fibers"},{"target_artifact_id":"wiki-cell-types-horizontal-cells-retina","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-horizontal-cells-retina"},{"target_artifact_id":"wiki-cell-types-spinal-lamina-ii-substantia-gelatinosa","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-spinal-lamina-ii-substantia-gelatinosa"},{"target_artifact_id":"wiki-cell-types-purkinje-cell-axonal-terminals","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-purkinje-cell-axonal-terminals"},{"target_artifact_id":"wiki-cell-types-median-raphe","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-median-raphe"},{"target_artifact_id":"wiki-cell-types-ventral-tegmental-area-gabaergic","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-ventral-tegmental-area-gabaergic"},{"target_artifact_id":"wiki-cell-types-main-olfactory-bulb","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-main-olfactory-bulb"},{"target_artifact_id":"wiki-cell-types-ventral-tegmental-area-expanded-v2","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-ventral-tegmental-area-expanded-v2"},{"target_artifact_id":"wiki-cell-types-ventral-pallidum","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-ventral-pallidum"},{"target_artifact_id":"wiki-cell-types-gaba-receptors-neurons","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-gaba-receptors-neurons"},{"target_artifact_id":"wiki-cell-types-triangular-nucleus-septern","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-triangular-nucleus-septern"},{"target_artifact_id":"wiki-cell-types-renshaw-cells-inhibition","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-renshaw-cells-inhibition"},{"target_artifact_id":"wiki-cell-types-golgi-cells","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-golgi-cells"},{"target_artifact_id":"wiki-cell-types-laterodorsal-tegmental-nucleus-expanded","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-laterodorsal-tegmental-nucleus-expanded"},{"target_artifact_id":"wiki-cell-types-hippocampal-pv-interneurons","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-hippocampal-pv-interneurons"},{"target_artifact_id":"wiki-cell-types-flocculus","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-flocculus"},{"target_artifact_id":"wiki-cell-types-horizonal-limb-diagonal-band","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-horizonal-limb-diagonal-band"},{"target_artifact_id":"wiki-cell-types-cortical-bipolar-cells","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-cortical-bipolar-cells"},{"target_artifact_id":"wiki-cell-types-hypothalamic-sleep-active","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-hypothalamic-sleep-active"},{"target_artifact_id":"wiki-cell-types-striatal-parvalbumin-interneurons","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-striatal-parvalbumin-interneurons"},{"target_artifact_id":"wiki-cell-types-cortical-basket-cells","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-cortical-basket-cells"},{"target_artifact_id":"wiki-cell-types-wernickes-area","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-wernickes-area"},{"target_artifact_id":"wiki-cell-types-intercalated-nucleus-amygdala-expanded","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-intercalated-nucleus-amygdala-expanded"},{"target_artifact_id":"wiki-cell-types-pars-reticularis-nigral","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-pars-reticularis-nigral"},{"target_artifact_id":"wiki-cell-types-stellate-cells-cerebellar","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-stellate-cells-cerebellar"},{"target_artifact_id":"wiki-cell-types-interpeduncular-nicotine","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-interpeduncular-nicotine"},{"target_artifact_id":"wiki-cell-types-dorsal-raphe","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-dorsal-raphe"},{"target_artifact_id":"wiki-cell-types-kolliker-fuse-subnucleus","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-kolliker-fuse-subnucleus"},{"target_artifact_id":"wiki-cell-types-anterior-hypothalamic-area","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-anterior-hypothalamic-area"},{"target_artifact_id":"wiki-cell-types-median-preoptic-nucleus-sleep","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-median-preoptic-nucleus-sleep"},{"target_artifact_id":"wiki-cell-types-habenula-mood-reward","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-habenula-mood-reward"},{"target_artifact_id":"wiki-cell-types-gabaergic-neuron-vulnerability","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-gabaergic-neuron-vulnerability"},{"target_artifact_id":"wiki-cell-types-globus-pallidus-internus","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-globus-pallidus-internus"},{"target_artifact_id":"wiki-cell-types-gat-neurons","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-gat-neurons"},{"target_artifact_id":"wiki-cell-types-parvalbumin-expressing-interneurons","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-parvalbumin-expressing-interneurons"},{"target_artifact_id":"wiki-cell-types-globus-pallidus-external","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-globus-pallidus-external"},{"target_artifact_id":"wiki-cell-types-habenula-reward","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-habenula-reward"},{"target_artifact_id":"wiki-cell-types-ventrolateral-preoptic-area","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-ventrolateral-preoptic-area"},{"target_artifact_id":"wiki-cell-types-ventrolateral-preoptic-gabaergic","link_type":"related","strength":0.54,"evidence":"Reverse: Content: MTOR mentioned 4x in wiki/cell-types-ventrolateral-preoptic-gabaergic"},{"target_artifact_id":"wiki-ai-tool-alibaba-tongyi-qianwen-bio","link_type":"related","strength":0.7,"evidence":"disease: neurodegeneration"},{"target_artifact_id":"wiki-proteins-mtor-protein-v2","link_type":"related","strength":0.6,"evidence":null},{"target_artifact_id":"wiki-genes-mtor","link_type":"related","strength":0.6,"evidence":null},{"target_artifact_id":"wiki-entities-mtor","link_type":"related","strength":0.6,"evidence":null},{"target_artifact_id":"wiki-events-mds-2026-parkinsons-diagnostics-biomarkers","link_type":"related","strength":0.6,"evidence":null},{"target_artifact_id":"wiki-neurodegeneration","link_type":"related","strength":0.8,"evidence":"Hypothesis relates to disease described in wiki"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-auto-fd6b1635d9","link_type":"derives_from","strength":0.95,"evidence":"Hypothesis derives from this analysis"},{"target_artifact_id":"wiki-events-mds-2026-parkinsons-diagnostics-biomarkers","link_type":"mentions","strength":0.9,"evidence":"Hypothesis targets gene MTOR"},{"target_artifact_id":"wiki-diseases-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Disease: neurodegeneration"},{"target_artifact_id":"wiki-genes-map1lc3b","link_type":"mentions","strength":0.5,"evidence":"Entity MAP1LC3B in hypothesis text"},{"target_artifact_id":"wiki-genes-ulk1","link_type":"mentions","strength":0.5,"evidence":"Entity ULK1 in hypothesis text"},{"target_artifact_id":"wiki-genes-treh","link_type":"mentions","strength":0.5,"evidence":"Entity TREH in hypothesis text"},{"target_artifact_id":"wiki-proteins-tau","link_type":"mentions","strength":0.5,"evidence":"Entity TAU in hypothesis text"},{"target_artifact_id":"wiki-genes-app","link_type":"mentions","strength":0.5,"evidence":"Entity APP in hypothesis text"},{"target_artifact_id":"wiki-genes-lamp1","link_type":"mentions","strength":0.5,"evidence":"Entity LAMP1 in hypothesis text"},{"target_artifact_id":"wiki-genes-becn1","link_type":"mentions","strength":0.5,"evidence":"Entity BECN1 in hypothesis text"},{"target_artifact_id":"wiki-genes-tfeb","link_type":"mentions","strength":0.5,"evidence":"Entity TFEB in hypothesis text"},{"target_artifact_id":"wiki-genes-ctsd","link_type":"mentions","strength":0.5,"evidence":"Entity CTSD in hypothesis text"},{"target_artifact_id":"wiki-genes-lc3","link_type":"mentions","strength":0.5,"evidence":"Entity LC3 in hypothesis text"},{"target_artifact_id":"wiki-genes-sqstm1","link_type":"mentions","strength":0.5,"evidence":"Entity SQSTM1 in hypothesis text"},{"target_artifact_id":"wiki-genes-ldlr","link_type":"mentions","strength":0.5,"evidence":"Entity LDLR in hypothesis text"},{"target_artifact_id":"wiki-genes-ctsb","link_type":"mentions","strength":0.5,"evidence":"Entity CTSB in hypothesis text"},{"target_artifact_id":"wiki-genes-abca1","link_type":"related","strength":0.4,"evidence":"KG bridge: ABCA1 ↔ MTOR"},{"target_artifact_id":"wiki-genes-abcg1","link_type":"related","strength":0.4,"evidence":"KG bridge: ABCG1 ↔ MTOR"},{"target_artifact_id":"wiki-entities-acetylcholine","link_type":"related","strength":0.4,"evidence":"KG bridge: ACETYLCHOLINE ↔ MTOR"},{"target_artifact_id":"wiki-mechanisms-acly-alpha-synuclein-autophagy","link_type":"related","strength":0.4,"evidence":"KG bridge: ACLY ↔ MTOR"},{"target_artifact_id":"wiki-genes-acsl4","link_type":"related","strength":0.4,"evidence":"KG bridge: ACSL4 ↔ MTOR"},{"target_artifact_id":"wiki-genes-actb","link_type":"related","strength":0.4,"evidence":"KG bridge: ACTB ↔ MTOR"},{"target_artifact_id":"wiki-genes-actn2","link_type":"related","strength":0.4,"evidence":"KG bridge: ACTN2 ↔ MTOR"},{"target_artifact_id":"wiki-genes-acvr1","link_type":"related","strength":0.4,"evidence":"KG bridge: ACVR1 ↔ MTOR"},{"target_artifact_id":"wiki-institutions-amp-ad","link_type":"related","strength":0.4,"evidence":"KG bridge: AD ↔ MTOR"},{"target_artifact_id":"wiki-genes-adam10","link_type":"related","strength":0.4,"evidence":"KG bridge: ADAM10 ↔ MTOR"},{"target_artifact_id":"wiki-genes-adam8","link_type":"related","strength":0.4,"evidence":"KG bridge: ADAM8 ↔ MTOR"},{"target_artifact_id":"wiki-genes-adrb2","link_type":"related","strength":0.4,"evidence":"KG bridge: ADRB2 ↔ MTOR"},{"target_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"related","strength":0.4,"evidence":"KG bridge: AGING ↔ MTOR"},{"target_artifact_id":"wiki-genes-mtor-v2","link_type":"targets","strength":0.9,"evidence":null},{"target_artifact_id":"wiki-cell-types-cochlear-hair-cells-aging","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: cell-types-cochlear-hair-cells-aging --activates--> MTOR (hypothesis target)"},{"target_artifact_id":"wiki-experiments-selective-neuronal-vulnerability-aging","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: experiments-selective-neuronal-vulnerability-aging --activates--> MTOR (hypothesis 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MTOR (hypothesis target)"},{"target_artifact_id":"wiki-genes-apoa1","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: genes-apoa1 --inhibits--> MTOR (hypothesis target)"},{"target_artifact_id":"wiki-proteins-app","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: proteins-app --activates--> MTOR (hypothesis target)"},{"target_artifact_id":"wiki-genes-arf1","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: genes-arf1 --activates--> MTOR (hypothesis target)"},{"target_artifact_id":"wiki-proteins-arf1","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: proteins-arf1 --activates--> MTOR (hypothesis target)"},{"target_artifact_id":"wiki-genes-arg1","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: genes-arg1 --inhibits--> MTOR (hypothesis target)"},{"target_artifact_id":"wiki-genes-arid1a","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: genes-arid1a --expressed_in--> MTOR (hypothesis target)"},{"target_artifact_id":"wiki-genes-asc","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: genes-asc --activates--> MTOR (hypothesis target)"},{"target_artifact_id":"wiki-proteins-mtor-protein-v2","link_type":"see_also","strength":0.7,"evidence":"Hypothesis targets gene MTOR discussed in wiki page"},{"target_artifact_id":"wiki-genes-mtor","link_type":"see_also","strength":0.7,"evidence":"Hypothesis targets gene MTOR discussed in wiki page"},{"target_artifact_id":"wiki-entities-mtor","link_type":"see_also","strength":0.7,"evidence":"Hypothesis targets gene MTOR discussed in wiki page"},{"target_artifact_id":"wiki-events-mds-2026-parkinsons-diagnostics-biomarkers","link_type":"see_also","strength":0.7,"evidence":"Hypothesis targets gene MTOR discussed in wiki page"},{"target_artifact_id":"wiki-convergence-synthesis-neuroinflammation-core","link_type":"supports","strength":0.88,"evidence":"Top-five source hypothesis supporting convergence synthesis convergence-synthesis-neuroinflammation-core [task:b010bbfa-414f-4bda-a1e6-ad769510df07]"},{"target_artifact_id":"wiki-convergence-synthesis-trem2-microglial-lipid-sensing","link_type":"supports","strength":0.88,"evidence":"Top-five source hypothesis supporting convergence synthesis convergence-synthesis-trem2-microglial-lipid-sensing [task:b010bbfa-414f-4bda-a1e6-ad769510df07]"},{"target_artifact_id":"wiki-convergence-synthesis-sphingolipid-ceramide-senescence","link_type":"supports","strength":0.88,"evidence":"Top-five source hypothesis supporting convergence synthesis convergence-synthesis-sphingolipid-ceramide-senescence [task:b010bbfa-414f-4bda-a1e6-ad769510df07]"},{"target_artifact_id":"wiki-convergence-synthesis-apoe-cholesterol-transport","link_type":"supports","strength":0.88,"evidence":"Top-five source hypothesis supporting convergence synthesis convergence-synthesis-apoe-cholesterol-transport [task:b010bbfa-414f-4bda-a1e6-ad769510df07]"},{"target_artifact_id":"wiki-convergence-synthesis-autophagy-lysosome-flux","link_type":"supports","strength":0.88,"evidence":"Top-five source hypothesis supporting convergence synthesis convergence-synthesis-autophagy-lysosome-flux [task:b010bbfa-414f-4bda-a1e6-ad769510df07]"}],"incoming_links":[{"source_artifact_id":"experiment-exp-eb97f425-ed39-4f3b-93f8-797ce348761e","link_type":"related","strength":1.0,"evidence":null},{"source_artifact_id":"wiki-therapeutics-baclofen","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/therapeutics-baclofen"},{"source_artifact_id":"wiki-therapeutics-growth-factor-therapies-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Content: MTOR mentioned 2x in wiki/therapeutics-growth-factor-therapies-neurodegeneration"},{"source_artifact_id":"wiki-therapeutics-sodium-oligomannate-gv971","link_type":"mentions","strength":0.5,"evidence":"Content: MTOR mentioned 2x in wiki/therapeutics-sodium-oligomannate-gv971"},{"source_artifact_id":"wiki-investment-growth-factor-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Content: MTOR mentioned 2x in wiki/investment-growth-factor-therapeutics"},{"source_artifact_id":"wiki-cell-types-tuberomammillary-nucleus-expanded","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-tuberomammillary-nucleus-expanded"},{"source_artifact_id":"wiki-cell-types-interstitial-nucleus-of-cajal","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-interstitial-nucleus-of-cajal"},{"source_artifact_id":"wiki-cell-types-spinal-cord-lamina-x","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-spinal-cord-lamina-x"},{"source_artifact_id":"wiki-cell-types-inferior-colliculus-localization","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-inferior-colliculus-localization"},{"source_artifact_id":"wiki-cell-types-ventral-pallidum-neurons-motivation","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-ventral-pallidum-neurons-motivation"},{"source_artifact_id":"wiki-cell-types-reticular-thalamic-nucleus-gabaergic","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-reticular-thalamic-nucleus-gabaergic"},{"source_artifact_id":"wiki-cell-types-reticular-nucleus-epilepsy","link_type":"mentions","strength":0.55,"evidence":"Content: MTOR mentioned 3x in wiki/cell-types-reticular-nucleus-epilepsy"},{"source_artifact_id":"wiki-cell-types-medial-septal-cholinergic","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-medial-septal-cholinergic"},{"source_artifact_id":"wiki-cell-types-tuberomammillary-histaminergic","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-tuberomammillary-histaminergic"},{"source_artifact_id":"wiki-cell-types-cortical-chandelier-cells","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-cortical-chandelier-cells"},{"source_artifact_id":"wiki-cell-types-laterodorsal-tegmental-nucleus-gabaergic","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-laterodorsal-tegmental-nucleus-gabaergic"},{"source_artifact_id":"wiki-cell-types-preoptic-area-gaehrens","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-preoptic-area-gaehrens"},{"source_artifact_id":"wiki-cell-types-striatal-horizontal-cells","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-striatal-horizontal-cells"},{"source_artifact_id":"wiki-cell-types-lateral-pericentral-nucleus-inferior-colliculus","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-lateral-pericentral-nucleus-inferior-colliculus"},{"source_artifact_id":"wiki-cell-types-dentate-gyrus-granule-cells-in-temporal-lobe-epilepsy","link_type":"mentions","strength":0.55,"evidence":"Content: MTOR mentioned 3x in wiki/cell-types-dentate-gyrus-granule-cells-in-temporal-lobe-epilepsy"},{"source_artifact_id":"wiki-cell-types-horizonal-diagonal-band","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-horizonal-diagonal-band"},{"source_artifact_id":"wiki-cell-types-globus-pallidus-internal-segment-gabaergic","link_type":"mentions","strength":0.6,"evidence":"Content: MTOR mentioned 4x in wiki/cell-types-globus-pallidus-internal-segment-gabaergic"},{"source_artifact_id":"wiki-cell-types-hippocampal-granule-cells-temporal-lobe-epilepsy","link_type":"mentions","strength":0.55,"evidence":"Content: MTOR mentioned 3x in 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