{"artifact":{"id":"hypothesis-h-91bdb9ad","artifact_type":"hypothesis","entity_ids":"[\"RHOT1\"]","title":"Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy","quality_score":0.5700000000000001,"created_by":"import","provenance_chain":null,"content_hash":"1fa2f3acd6b668300b59e395b2b4f197526566decfb77ef91697b262b21c2f15","metadata":{"status":"proposed","disease":"neurodegeneration","analysis_id":"SDA-2026-04-01-gap-20260401231108","target_gene":"RHOT1","target_pathway":null,"_schema_version":1,"composite_score":0.5700000000000001},"created_at":"2026-04-02T20:53:40-07:00","updated_at":"2026-04-02T16:29:15.497291-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T20:53:40-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"3ed8c6e2-3038-46a5-a3f3-4759475808c8","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"import"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"wiki-diseases-daly-methodology-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-us-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-manganism","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-clinical-trials-beacon-study-nct03860857","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-clinical-trials-olfactory-mucosa-early-neurodegeneration-nct06846658","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-clinical-trials-gut-brain-axis-neurodegeneration-nct05934188","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-clinical-trials-swedish-biofinder-2-psp-nct03174938","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-genes-nf1","link_type":"related","strength":0.54,"evidence":"Reverse: KG edge: NF1 connects to RHOT1"},{"target_artifact_id":"wiki-mitochondrial_complex_I","link_type":"related","strength":0.54,"evidence":"Reverse: Wiki page 'mitochondrial_complex_I' — entity matches hypothesis target"},{"target_artifact_id":"wiki-mitochondrial_dysfunction","link_type":"related","strength":0.54,"evidence":"Reverse: Wiki page 'mitochondrial_dysfunction' — entity matches hypothesis target"},{"target_artifact_id":"wiki-mitochondria","link_type":"related","strength":0.54,"evidence":"Reverse: Wiki page 'mitochondria' — entity matches hypothesis target"},{"target_artifact_id":"wiki-diseases-nbia","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-mpan","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-india-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-pla2g6-associated-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-bpan","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-japan-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-european-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-economic-burden-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-global-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-neurodegeneration-impact-measures","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-pantothenate-kinase-associated-neurodegeneration-pkan","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-china-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-disease-progression","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-sleep-disorders-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-pkan","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-mitochondrial-dysfunction-neurodegeneration-comparison","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-familial-vs-sporadic-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-mitochondrial-neurodegeneration-comparison","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-proteins-miro2-protein","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: RHOT1"},{"target_artifact_id":"wiki-proteins-miro1-protein","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: RHOT1"},{"target_artifact_id":"wiki-proteins-perk","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: RHOT1"},{"target_artifact_id":"wiki-proteins-chop","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: RHOT1"},{"target_artifact_id":"wiki-genes-miro2","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: RHOT1"},{"target_artifact_id":"wiki-mechanisms-tunneling-nanotubes","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: RHOT1"},{"target_artifact_id":"wiki-mechanisms-axonal-transport","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-alpers-huttenlocher-syndrome-mtdna-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-abca7-lipid-transport-microglial-phagocytosis-ad-causal-chain","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-axonal-transport-4r-tauopathies","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-electron-transport-chain","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-axonal-transport-dysfunction-comparison","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-axonal-transport-defects","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-nucleocytoplasmic-transport-defects","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-dynein","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-axonal-transport-pd-validation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-axonal-transport-psp","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-nucleocytoplasmic-transport-4r-tauopathies","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-exercise-bdnf-mitophagy-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-amyloid-beta-trans-synaptic-spread-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-retrograde-transport-endosomal-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-glutamate-transport","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-mlcs-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-metal-ion-synuclein-mitochondria-axis","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-mitochondria-lysosome-contact-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-nucleocytoplasmic-transport-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-mtdna-mutations-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-retrograde-axonal-transport-dysfunction","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-glymphatic-transport-optic-nerve","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-neuroinflammation-mitochondria-crosstalk","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-mitochondria-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-cbs-axonal-transport","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-mitochondria-lysosome-contact-sites","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-cytoskeletal-dynamics-axonal-transport","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-bbb-transport-mechanisms","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"target_artifact_id":"wiki-mechanisms-blood-brain-barrier","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Blood-Brain Barrier"},{"target_artifact_id":"wiki-diseases-stroke","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Stroke"},{"target_artifact_id":"wiki-entities-oligodendrocytes","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Oligodendrocytes"},{"target_artifact_id":"wiki-cell-types-blood-brain-barrier","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Blood-Brain Barrier"},{"target_artifact_id":"wiki-therapeutics-levodopa","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: levodopa"},{"target_artifact_id":"wiki-diseases-parkinsons-disease","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Parkinson's Disease"},{"target_artifact_id":"wiki-proteins-kinesin-1a-protein","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Kinesin-1 Heavy Chain"},{"target_artifact_id":"wiki-institutions-biogen","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Biogen"},{"target_artifact_id":"wiki-diseases-huntingtons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Huntington's Disease"},{"target_artifact_id":"wiki-companies","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Companies"},{"target_artifact_id":"wiki-diseases-als","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Amyotrophic Lateral Sclerosis (ALS)"},{"target_artifact_id":"wiki-therapeutics-riluzole","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: riluzole"},{"target_artifact_id":"wiki-companies-biogen","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Biogen"},{"target_artifact_id":"wiki-ai-tool-alibaba-tongyi-qianwen-bio","link_type":"related","strength":0.7,"evidence":"disease: neurodegeneration"},{"target_artifact_id":"wiki-als","link_type":"related","strength":0.4,"evidence":"KG bridge: ALS ↔ RHOT1"},{"target_artifact_id":"wiki-mechanisms-mitochondrial-complex-iii","link_type":"related","strength":0.4,"evidence":"KG bridge: ATP ↔ RHOT1"},{"target_artifact_id":"wiki-proteins-rhot1","link_type":"related","strength":0.6,"evidence":null},{"target_artifact_id":"wiki-genes-rhot1","link_type":"related","strength":0.6,"evidence":null},{"target_artifact_id":"wiki-neurodegeneration","link_type":"related","strength":0.8,"evidence":"Hypothesis relates to disease described in wiki"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401231108","link_type":"derives_from","strength":0.95,"evidence":"Hypothesis derives from this analysis"},{"target_artifact_id":"wiki-genes-rhot1","link_type":"mentions","strength":0.9,"evidence":"Hypothesis targets gene RHOT1"},{"target_artifact_id":"wiki-diseases-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Disease: neurodegeneration"},{"target_artifact_id":"wiki-genes-sod1","link_type":"mentions","strength":0.5,"evidence":"Entity SOD1 in hypothesis text"},{"target_artifact_id":"wiki-genes-app","link_type":"mentions","strength":0.5,"evidence":"Entity APP in hypothesis text"},{"target_artifact_id":"wiki-genes-pink1","link_type":"mentions","strength":0.5,"evidence":"Entity PINK1 in hypothesis text"},{"target_artifact_id":"wiki-proteins-huntingtin","link_type":"mentions","strength":0.5,"evidence":"Entity huntingtin in hypothesis text"},{"target_artifact_id":"wiki-proteins-dynein","link_type":"mentions","strength":0.5,"evidence":"Entity dynein in hypothesis text"},{"target_artifact_id":"wiki-genes-abcd3","link_type":"related","strength":0.4,"evidence":"KG bridge: ABCD3 ↔ RHOT1"},{"target_artifact_id":"wiki-institutions-amp-ad","link_type":"related","strength":0.4,"evidence":"KG bridge: AD ↔ RHOT1"},{"target_artifact_id":"wiki-institutions-packard-center-als","link_type":"related","strength":0.4,"evidence":"KG bridge: ALS ↔ RHOT1"},{"target_artifact_id":"wiki-institutions-alzheimer-indonesia","link_type":"related","strength":0.4,"evidence":"KG bridge: ALZHEIMER ↔ RHOT1"},{"target_artifact_id":"wiki-diseases-alzheimers-disease","link_type":"related","strength":0.4,"evidence":"KG bridge: ALZHEIMER'S DISEASE ↔ RHOT1"},{"target_artifact_id":"wiki-genes-ambra1","link_type":"related","strength":0.4,"evidence":"KG bridge: AMBRA1 ↔ RHOT1"},{"target_artifact_id":"wiki-entities-ampk","link_type":"related","strength":0.4,"evidence":"KG bridge: AMPK ↔ RHOT1"},{"target_artifact_id":"wiki-diseases-amyotrophic-lateral-sclerosis","link_type":"related","strength":0.4,"evidence":"KG bridge: AMYOTROPHIC LATERAL SCLEROSIS ↔ RHOT1"},{"target_artifact_id":"wiki-entities-apoptosis","link_type":"related","strength":0.4,"evidence":"KG bridge: APOPTOSIS ↔ RHOT1"},{"target_artifact_id":"wiki-entities-astrocytes","link_type":"related","strength":0.4,"evidence":"KG bridge: ASTROCYTES ↔ RHOT1"},{"target_artifact_id":"wiki-genes-atm","link_type":"related","strength":0.4,"evidence":"KG bridge: ATM ↔ RHOT1"},{"target_artifact_id":"wiki-cell-types-p2x3-receptor-neurons","link_type":"related","strength":0.4,"evidence":"KG bridge: ATP ↔ RHOT1"},{"target_artifact_id":"wiki-experiments-autophagy-enhancement-drug-screening","link_type":"related","strength":0.4,"evidence":"KG bridge: AUTOPHAGY ↔ RHOT1"},{"target_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"related","strength":0.4,"evidence":"KG bridge: Aging ↔ RHOT1"},{"target_artifact_id":"wiki-genes-rhot1","link_type":"targets","strength":0.9,"evidence":null},{"target_artifact_id":"wiki-genes-kif17","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif24","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif27","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-dync2h1","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'DYNEIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif22","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif20b","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif26b","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif1b","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif25","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif9","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif3c","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif26a","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-genes-kif20a","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'KINESIN' found in hypothesis pathway"},{"target_artifact_id":"wiki-diseases-als","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: diseases-als --activates--> RHOT1 (hypothesis target)"},{"target_artifact_id":"wiki-cell-types-hippocampal-ca3-neurons-alzheimer","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: cell-types-hippocampal-ca3-neurons-alzheimer --activates--> RHOT1 (hypothesis target)"},{"target_artifact_id":"wiki-cell-types-microglia-neurodegeneration-alzheimer","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: cell-types-microglia-neurodegeneration-alzheimer --activates--> RHOT1 (hypothesis target)"},{"target_artifact_id":"wiki-researchers-alois-alzheimer","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: researchers-alois-alzheimer --activates--> RHOT1 (hypothesis target)"},{"target_artifact_id":"wiki-mechanisms-apoptosis","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: mechanisms-apoptosis --activates--> RHOT1 (hypothesis target)"},{"target_artifact_id":"wiki-proteins-rhot1","link_type":"see_also","strength":0.7,"evidence":"Hypothesis targets gene RHOT1 discussed in wiki page"},{"target_artifact_id":"wiki-genes-rhot1","link_type":"see_also","strength":0.7,"evidence":"Hypothesis targets gene RHOT1 discussed in wiki page"}],"incoming_links":[{"source_artifact_id":"wiki-technologies-crispr-cas9","link_type":"mentions","strength":0.5,"evidence":"Content: RHOT1 mentioned 2x in wiki/technologies-crispr-cas9"},{"source_artifact_id":"wiki-proteins-nsf-protein","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-91bdb9ad: ...herapy](/hypothesis/h-91bdb9ad) — <span style=\"col..."},{"source_artifact_id":"wiki-genes-nsf","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-91bdb9ad: ...herapy](/hypothesis/h-91bdb9ad) — <span style=\"col..."},{"source_artifact_id":"wiki-genes-fer","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-91bdb9ad: ...herapy](/hypothesis/h-91bdb9ad) — <span style=\"col..."},{"source_artifact_id":"wiki-ai-tool-alibaba-tongyi-qianwen-bio","link_type":"related","strength":0.7,"evidence":"disease: neurodegeneration"},{"source_artifact_id":"wiki-als","link_type":"related","strength":0.4,"evidence":"KG bridge: ALS ↔ RHOT1"},{"source_artifact_id":"wiki-proteins-rhot1","link_type":"mentions","strength":0.7,"evidence":null},{"source_artifact_id":"wiki-genes-rhot1","link_type":"mentions","strength":0.7,"evidence":null},{"source_artifact_id":"wiki-genes-parkin","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'PARKIN Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-neurodegeneration","link_type":"related","strength":0.8,"evidence":"Wiki disease page related to hypothesis about neurodegeneration"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-20260401231108","link_type":"derives_from","strength":0.95,"evidence":"Hypothesis generated from analysis debate"},{"source_artifact_id":"wiki-genes-nf1","link_type":"related","strength":0.6,"evidence":"KG edge: NF1 connects to RHOT1"},{"source_artifact_id":"wiki-mitochondrial_complex_I","link_type":"mentions","strength":0.6,"evidence":"Wiki page 'mitochondrial_complex_I' — entity matches hypothesis target"},{"source_artifact_id":"wiki-mitochondrial_dysfunction","link_type":"mentions","strength":0.6,"evidence":"Wiki page 'mitochondrial_dysfunction' — entity matches hypothesis target"},{"source_artifact_id":"wiki-mitochondria","link_type":"mentions","strength":0.6,"evidence":"Wiki page 'mitochondria' — entity matches hypothesis target"},{"source_artifact_id":"wiki-hand","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'hand' — entity matches hypothesis target"},{"source_artifact_id":"wiki-late","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'late' — entity matches hypothesis target"},{"source_artifact_id":"wiki-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'neurodegeneration' — entity matches hypothesis target"},{"source_artifact_id":"wiki-home","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'NeuroWiki' — entity matches hypothesis target"},{"source_artifact_id":"wiki-therapeutics-neuroprotection","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Neuroprotection Strategies in Neurodegeneration' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-pink1","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'PINK1 Protein' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-parkin","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Parkin' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-dynein","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Dynein — Cytoplasmic Dynein 1' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-huntingtin","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Huntingtin (HTT)' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-rela","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'NF-κB p65 Protein' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-sod1","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'SOD1 Protein' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-pink1-protein","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'PINK1' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-huntingtin_protein","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Huntingtin Protein' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-dysf","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'DYSF — Dysferlin' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-rela","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'RELA (NF-κB p65)' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-idua","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'IDUA Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-syna","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'syna' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-terc","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'TERC Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-rest","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'REST Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-spast","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'SPAST' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-sod1","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'sod1' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-pink1","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'PINK1 — PTEN Induced Kinase 1' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-ralb","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'RALB Gene - RAS-Related Protein Ral-B' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-myot","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'MYOT Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-mechanisms-dynein","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Dynein Motor Protein' — entity matches hypothesis target"},{"source_artifact_id":"wiki-diseases-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Neurodegeneration' — entity matches hypothesis target"},{"source_artifact_id":"wiki-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'biomarkers' — entity matches hypothesis target"},{"source_artifact_id":"wiki-diseases","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'diseases' — entity matches hypothesis target"},{"source_artifact_id":"wiki-treatments","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'treatments' — entity matches hypothesis target"},{"source_artifact_id":"wiki-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'therapeutics' — entity matches hypothesis target"},{"source_artifact_id":"wiki-mechanisms","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'mechanisms' — entity matches hypothesis target"},{"source_artifact_id":"wiki-experiments","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'experiments' — entity matches hypothesis target"},{"source_artifact_id":"wiki-hypotheses","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'hypotheses' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Genes' — entity matches hypothesis target"},{"source_artifact_id":"wiki-models","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Models' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Proteins' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-rhot1","link_type":"related","strength":0.7,"evidence":"Wiki entity matches hypothesis target gene RHOT1"},{"source_artifact_id":"wiki-genes-rhot1","link_type":"related","strength":0.7,"evidence":"Wiki entity matches hypothesis target gene RHOT1"},{"source_artifact_id":"wiki-diseases-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-genes-app","link_type":"mentions","strength":0.5,"evidence":"Entity APP in hypothesis text"},{"source_artifact_id":"wiki-genes-abcd3","link_type":"related","strength":0.4,"evidence":"KG bridge: ABCD3 ↔ RHOT1"},{"source_artifact_id":"wiki-institutions-amp-ad","link_type":"related","strength":0.4,"evidence":"KG bridge: AD ↔ RHOT1"},{"source_artifact_id":"wiki-institutions-packard-center-als","link_type":"related","strength":0.4,"evidence":"KG bridge: ALS ↔ RHOT1"},{"source_artifact_id":"wiki-institutions-alzheimer-indonesia","link_type":"related","strength":0.4,"evidence":"KG bridge: ALZHEIMER ↔ RHOT1"},{"source_artifact_id":"wiki-diseases-alzheimers-disease","link_type":"related","strength":0.4,"evidence":"KG bridge: ALZHEIMER'S DISEASE ↔ RHOT1"},{"source_artifact_id":"wiki-genes-ambra1","link_type":"related","strength":0.4,"evidence":"KG bridge: AMBRA1 ↔ RHOT1"},{"source_artifact_id":"wiki-entities-ampk","link_type":"related","strength":0.4,"evidence":"KG bridge: AMPK ↔ RHOT1"},{"source_artifact_id":"wiki-diseases-amyotrophic-lateral-sclerosis","link_type":"related","strength":0.4,"evidence":"KG bridge: AMYOTROPHIC LATERAL SCLEROSIS ↔ RHOT1"},{"source_artifact_id":"wiki-entities-apoptosis","link_type":"related","strength":0.4,"evidence":"KG bridge: APOPTOSIS ↔ RHOT1"},{"source_artifact_id":"wiki-entities-astrocytes","link_type":"related","strength":0.4,"evidence":"KG bridge: ASTROCYTES ↔ RHOT1"},{"source_artifact_id":"wiki-genes-atm","link_type":"related","strength":0.4,"evidence":"KG bridge: ATM ↔ RHOT1"},{"source_artifact_id":"wiki-cell-types-p2x3-receptor-neurons","link_type":"related","strength":0.4,"evidence":"KG bridge: ATP ↔ RHOT1"},{"source_artifact_id":"wiki-experiments-autophagy-enhancement-drug-screening","link_type":"related","strength":0.4,"evidence":"KG bridge: AUTOPHAGY ↔ RHOT1"},{"source_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"related","strength":0.4,"evidence":"KG bridge: Aging ↔ RHOT1"},{"source_artifact_id":"wiki-genes-bnip3","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-genes-bnip3l","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-proteins-panx1","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-genes-panx1","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-genes-rab27a","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-proteins-gja1","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-genes-gja1","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-mechanisms-psp-mitochondrial-dysfunction","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-lrrk2-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-dynamics-modulators","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nrf2-activator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-aav-gene-therapy-neurodevelopmental-epilepsy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-corticobasal-degeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-comparison","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-144-advanced-myelin-repair-oligodendrocyte-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-carbonic-anhydrase-modulator-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sting-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-autophagy-enhancement-tauopathy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-s100-protein-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-aav-cns-gene-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-neuroprotection","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-photobiomodulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-huntingtons-biomarkers-and-precision-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-intranasal-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dna-replication","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-exercise-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-brain-computer-interface-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sgc-stimulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-antisense-oligonucleotide-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-enzyme-replacement-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-melatonin-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mtor-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-treg-regulatory-t-cell-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sleep-optimization-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-targeted-protein-stabilization-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-galectin-3-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-neural-stem-cell-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-combination-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-186-bioenergetics-mitochondrial-coupling-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-astrocyte-metabolic-enhancement-pd","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-ampk-mitochondrial-quality-control","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-iron-chelation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-hif-1-alpha-stabilization-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-fgf-fgfr-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-oligodendrocyte-precursor-cell-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-pathway","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-p2x7-receptor-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-microbiome-gut-brain-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-melatonin-agonist-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cbs-psp-metal-chelation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-vegf-angiogenesis-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-personalized-aso-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-atn-biomarker-guided-ad-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cbs-psp-nutritional-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nfl-blood-test-guided-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-rmf-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-ad","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-unfolded-protein-response","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-iron-chelation-therapy-parkinsons-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-ad-combination-therapy-matrix","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-lymphatic-glymphatic-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-201-advanced-mitochondrial-biogenesis-pgc1alpha-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-241-advanced-gene-therapy-crispr-approaches-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-physical-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-bdnf-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-hyperbaric-oxygen-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sigma-2-receptor-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-aav-gene-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-201-mitochondrial-biogenesis-pgc1alpha-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-tau-gene-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cognitive-stimulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-biogenesis-inducers","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nad-precursor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-modulators-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-228-advanced-dance-movement-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mrna-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-natural-compounds-phyto-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ire1-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-neurotensin-receptor-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nt-3-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-162-advanced-antioxidant-redox-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-microglia-modulation-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-probiotic-microbiome-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-trem2-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-237-advanced-humor-laughter-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-spinal-cord-stimulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-193-advanced-integrated-cell-stress-response-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ipsc-therapy-parkinsons-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-134-advanced-lipidomics-membrane-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sialic-acid-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-car-t-cell-therapy-alzheimers","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-failure-nodes-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nitric-oxide-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-metal-chelation-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ghrelin-ghsr-modulator-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-hub","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-fusion-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-aso-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-membrane-trafficking-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-protac-therapy-parkinsons-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-molecular-hydrogen-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-photobiomodulation-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-isr-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-vegf-angiogenesis-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-parp-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-secretoneurin-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-protein-trafficking-pathways","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-127-cell-therapy-transplantation-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-exosome-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-aim2-inflammasome-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-microglial-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ripk1-inhibitor-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gene-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-182-scfa-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-137-metal-chelation-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-galectin-3-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-136-glycomics-glycobiology-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-206-advanced-heat-shock-protein-molecular-chaperone-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-replacement-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-synaptic-vesicle-trafficking-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-quality-control","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mesenchymal-stem-cell-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-necroptosis-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gene-silencing-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nutritional-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-car-astrocyte-therapy-ad","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ripk1-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-217-advanced-cell-therapy-regenerative-medicine-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-proteostasis-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-synaptic-vesicle-trafficking-pathway","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-dance-movement-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-trem2-agonist-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-physical-therapy-exercise-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-complex-iv","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-melatonin-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-chchd10-mitochondrial-dysfunction-als-ftd-causal-chain","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-extracellular-matrix-integrin-modulator-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-transplantation-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-gene-mechanism-therapy-causal-chains","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-amylin-pramlintide-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-rock-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-complex-ii","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-113-emerging-gene-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ephb-receptor-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-209-advanced-cholinergic-system-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-irisin-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-187-advanced-cytokine-chemokine-network-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cd33-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-126-circadian-amplitude-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-proteins-mitochondrial-carrier-ata-1","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-combination-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-als-ftd","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-glial-cells","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-lrrk2-gba-combination-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-biogenesis-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-aav-gene-therapy-vectors-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-227-age-rage-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-153-virtual-reality-therapy-protocols-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cx3cr1-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-antisense-oligonucleotide-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-d-serine-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-astrocyte-metabolic-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-h2s-donor-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-physical-therapy-rehabilitation","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-phagocytosis-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-demyelination-remyelination-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mesenchymal-stem-cell-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-stem-cell-therapy-parkinsonism","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-er-stress-upr-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cannabinoid-receptor-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-pd-mitochondrial-dysfunction","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-nanobody-therapy-neurodegenerative-diseases","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-endosomal-trafficking-disease-comparison","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-antibody-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-car-t-cell-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cxcl12-cxcr4-axis-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nfat-pathway-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-speech-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-pyroptosis-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-music-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-239-advanced-light-therapy-photobiomodulation-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cdnf-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-dna-damage-repair-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-neurturin-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mtor-inhibitor-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-antisense-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-antioxidant-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-stem-cell-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-isr-modulator-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-occupational-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-ad-pathway","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-specialized-pro-resolving-mediator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-231-advanced-yoga-mind-body-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-synaptic-vesicle-trafficking","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-pd-synaptic-vesicle-trafficking-pathway","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-alpha7-nachr-agonist-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-progranulin-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gut-microbiome-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ipsc-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-microbiome-metabolomics-scfa-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-155-art-therapy-creative-arts-therapies-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-advanced-myelin-white-matter-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-combination-therapy-multi-target-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-somatostatin-receptor-modulator-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-mitochondrial-quality-control","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-neurotrophic-factor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-endolysosomal-trafficking-defects","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-specialized-pro-resolving-mediator-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ivig-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-antibody-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gba-gene-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-227-advanced-glycation-end-products-rage-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-disease-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-atp-synthesis","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-glymphatic-csf-enhancement-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-quality-control-network-pathway","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-vestibular-balance-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-somatic-movement-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-crispr-cas9-gene-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-lrrk2-antisense-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-speech-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-glymphatic-system-enhancement","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-physical-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-als","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-194-mitochondrial-dynamics-biogenesis-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-bci-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ketone-body-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-229-horticulture-therapy-nature-based-interventions-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-p2y12-receptor-antagonist-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-psp-mitochondrial-complex-i","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sirna-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-myo10-mitochondrial-transfer","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ad-combination-therapy-matrix","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-permeability-transition-pore","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-225-advanced-speech-communication-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sarm1-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-proteins-mitochondrial-carrier-family","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-247-advanced-sleep-circadian-rhythm-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-tgf-beta-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-neurotrophic-factor-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-glymphatic-enhancement-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-complement-inhibitor-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-bright-light-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-249-advanced-lsvt-voice-speech-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-fission-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-iron-chelation-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-music-rhythm-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cell-replacement-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-113-speech-language-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-251-advanced-vision-eye-movement-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-141-advanced-neurotrophin-growth-factor-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-gba-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-virtual-reality-therapy-cbs-psp-gait","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-therapeutics","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-physical-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-physical-therapy-rehabilitation-atypical-parkinsonism","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-4r-tauopathies","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-neuroimmune-metabolic-convergence-therapy-synthesis","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ahr-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-156-pet-therapy-animal-assisted-interventions-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-anti-tau-aggregation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-cbs-vesicle-trafficking","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-combination-therapy-synergies-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-181-advanced-music-rhythm-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-188-advanced-lipidomics-membrane-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sonogenetics-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mirna-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cell-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-neurotrophic-gene-therapy-programs","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-alpha-synuclein-antisense-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-pyroptosis-inhibition-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-endosomal-lysosomal-trafficking-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-dreadds-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-endocannabinoid-system-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-dna-repair-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ferroptosis-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-klotho-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ipsc-cell-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-aadc-gene-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-pp2a-activator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cgas-sting-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-trkb-modulator-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-antioxidant-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-il34-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-complex-iii","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-metabotropic-glutamate-receptor-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ferroptosis-therapy-parkinsons-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-physical-therapy-atypical-parkinsonism","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-monoclonal-antibody-therapy-alzheimers-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-138-advanced-extracellular-matrix-integrin-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-fusion-fission","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-csf-glymphatic-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gpr37-modulator-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-192-advanced-epigenomics-chromatin-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-combination-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-llps-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-lithium-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-251-peptide-hormone-gpcr-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-trem2-gene-mechanism-therapy-chain","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-194-mitochondrial-dynamics-biogenesis-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-cbd-mitochondrial-dysfunction","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-106-gene-therapy-vectors-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cerebrolysin-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gpr6-modulator-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-taar-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-250-advanced-nitric-oxide-gasotransmitter-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-progranulin-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gpr68-modulator-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-molecular-chaperone-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-tau-aso-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-242-advanced-stem-cell-therapy-neuronal-replacement-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-125-ketogenic-metabolic-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-200-epigenetic-chromatin-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-art-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-vitamin-d-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-miro1-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-atp13a2-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-psp-cell-specific-mitochondrial-response","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nutritional-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-dpp-4-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-astrocyte-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-estrogen-replacement-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-pannexin-hemichannel-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-syk-kinase-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-huntingtin-mitochondrial-dysfunction","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-mitochondrial-dysfunction-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cerebrolysin-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-isrib-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-254-lsvt-big-therapy-pt-ot-integration-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-dopamine-replacement-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-carbon-monoxide-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-dynamics-modulators-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-stem-cell-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-rgma-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-csf1r-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-pgc1alpha-mitochondrial-biogenesis-comparison","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-194-membrane-trafficking-vesicle-dynamics-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-speech-language-therapy-neurodegenerative-diseases","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-182-microbiome-metabolomics-scfa-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-neuroinflammation-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-als-combination-therapy-matrix","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-tau-pet-guided-anti-tau-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-faah-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cd47-sirp-alpha-immune-checkpoint-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-complement-c3-c5-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-music-therapy-neurodegenerative-diseases","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-massage-therapy-bodywork-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-pd-combination-therapy-matrix","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-sirt2-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-lysosomal-lipid-trafficking-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-apolipoprotein-lipid-transport-therapy-landscape","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-exosome-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-astrocytic-mitochondrial-transfer-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-253-respiratory-function-dysphagia-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-249-peptide-hormone-gpcr-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-biomarker-guided-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-226-proteoglycan-basement-membrane-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-scfa-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-saa-guided-alpha-synuclein-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-250-advanced-vestibular-balance-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-hyperbaric-oxygen-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-metabolic-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-aav-gene-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-parkin-gene-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-exosome-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-endosomal-trafficking-4r-tauopathies","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-metabolic-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-dance-movement-therapy-parkinson-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-prion-disease-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-membrane-protein-associated-neurodegeneration-mpan","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nfl-reduction-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-228-dance-movement-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-complement-c1q-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-mitochondrial-dynamics-neuron","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-203-advanced-epigenetic-chromatin-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-rage-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-sorl1-app-trafficking-retromer-ad-causal-chain","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-240-advanced-narrative-therapy-life-review-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-il-33-st2-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-anti-inflammatory-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-tgr5-agonist-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-250-advanced-gasotransmitter-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-opc-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-nurr1-agonist-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cell-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-antiepileptic-drugs-app-trafficking","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-vcp-targeted-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gaba-receptor-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-intranasal-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-cd38-inhibitor-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-sirtuin-mitochondrial-biogenesis-axis","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-endosomal-trafficking","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gdnf-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-215-combination-therapy-synergies-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-aav-vectors-neurodegenerative-gene-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-advanced-cytoskeletal-dynamics-modulator-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-microglial-priming-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gsk3-inhibitor-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-tam-receptor-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-n-acetylcysteine-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gene-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-occupational-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-rock-inhibitor-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gba-gene-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-park7-dj1-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-127-circadian-amplitude-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-189-advanced-autophagy-endolysosomal-pathway-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-205-advanced-myelin-white-matter-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-retinoid-pathway-modulator-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-psychobiotic-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-vestibular-rehabilitation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-ceramide-sphingolipid-modulation-therapy","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-dnajc13-endosomal-trafficking-pd-causal-chain","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-rna-targeting-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-gpr65-modulator-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-mesenchymal-stem-cell-therapy-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-antisense-oligonucleotide-therapy-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-mitochondrial-dysfunction-dopaminergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-investment-amyloid-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-beta-exposed","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-beta-cortical-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-responsive-microglia","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-accumulating-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-beta-exposed-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-calcium-dysregulation-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-calcium-homeostasis-modulators","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-calcium-signaling-investment","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-calcium-channel-blockers-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-calcium-homeostasis-modulation-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-calcium-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-calcium-binding-protein-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-calcium-dysregulation-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-calcium-dysregulated-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-calcium-homeostasis-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-psp","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-signaling-dysregulation","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-channel-dysfunction-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-homeostasis-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-comparison","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-excitotoxicity-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-channel-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbs-calcium-dysregulation","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-dysregulation-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-buffering-proteins-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-calcium-signaling-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'CALCIUM' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-connectivity-tacs-early-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-brain-computer-interface-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-brain-drug-delivery-challenges","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-brain-activity-walking-atypical-parkinsonism-nct06906276","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-brain-hyperconnectivity-tau-spread-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-brain-computer-interface","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-vascular-endothelial-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-organoids","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-capillary-endothelial-cells-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-endothelial-cells-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-endothelial-cells-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-venous-endothelial-cells-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-pericytes-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-endothelial-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-pericytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-ependymal-cells-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-pericytes-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-reserve-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-volume-changes-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-region-therapeutic-targeting-index","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-endothelial-cell-dysfunction-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-4r-tauopathies-brain-region-vulnerability","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-insulin-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-age-gap-amyloid-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-multiple-system-atrophy","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-parkinsons-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-knowledge-platform","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-to-brain-interface","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-organoids","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-lewy-body-dementia","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-vascular-dementia","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-frontotemporal-dementia","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-progressive-supranuclear-palsy","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-corticobasal-degeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-shuttles","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-organoids-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-computer-interfaces","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-technology-landscape","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-computer-interface","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-als","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-index","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-normal-pressure-hydrocephalus","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-waste-clearance-therapies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-organoid-silicon-interface","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-shuttle-technologies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-huntingtons-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-events-brain-health-roundtable-aadapt-act","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-brain-health-roundtable-aadapt-act","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-brain-insulin-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-connectivity","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-disease-involvement","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-vulnerability-map","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-brain-connectivity-tacs-early-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-brain-behavior-research-foundation","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-oligodendrocyte-precursor-cell-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-oligodendrocyte-myelin-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-opc-activation-myelin-regeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-oligodendrocyte-protection-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocyte-precursor-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocyte-precursor-cells-demyelination","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocyte-progenitor-cells-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocyte-lineage-in-multiple-system-atrophy","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocyte-lineage-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocyte-precursor-cells-opcs","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-opc-pvl","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-oligodendrocyte-dysfunction-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-oligodendrocyte-dysfunction-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-oligodendrocyte-precursor-differentiation-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-oligodendrocyte-pathology-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbs-oligodendrocyte-myelin-dysfunction","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-oligodendrocyte-neuron-metabolic-support","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-oligodendrocyte-myelin-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-complement-inhibitor-therapy-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-complement-c1q-inhibitor-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-complement-pathway-inhibition-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-complement-system-therapeutics-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-coagulation-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-system-activation-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-activation-cbd","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-mediated-synapse-loss","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-tauopathies-cbs","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-system-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-system-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-complement-c3","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-gaps-complement-system-dysregulation-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-dopamine-agonists","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-dopamine-replacement-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-dopamine-agonists-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-msa","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d3-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-adhd","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d1-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d5-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-vta-dopamine-reward","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-fxtas","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d2-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-drd","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-transporter-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d4-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dat-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-reward","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-transporter-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dat-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-pd-dopamine-metabolism","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-metabolism","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-biosynthesis-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-oxidation","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-dopamine","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-dopamine-d3-d4-selective-agonists","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-dopamine-metabolism-enzymes-beyond-comt","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-dopamine-transporter-modulators","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-intranasal-brain-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-intrathecal-drug-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-liposome-brain-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-convection-enhanced-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-nanoparticle-drug-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-exosome-brain-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-crispr-brain-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-cell-based-brain-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-nanoparticle-brain-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-aso-brain-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-lipid-nanoparticle-cns-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-intranasal-drug-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-exosome-cns-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-lipid-nanoparticle-cns-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-pd-neurotrophin-gdnf-delivery","link_type":"mentions","strength":0.5,"evidence":"Entity 'DELIVERY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-amyloid-vaccines","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-amyloid-plaque-neurofibrillary-tangle-depositi","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-cellular-uptake","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-tau-synergistic-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-conformational-strains","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-cellular-uptake-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-tau-synergistic-interaction-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-oligomers-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-trans-synaptic-spread-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-cascade-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-vs-tau-first","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-aggregation","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-clearance-therapeutic-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-oligomerization-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-cascade-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-fibril-formation","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-cascade","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-degradation-pathways","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-vs-tau-first-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-fibril-formation-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-metalloproteinases","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-amyloid-beta-40-abeta-40","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-amyloid-pet-imaging","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-amyloid-pet","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-app-protein","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-aria-imaging","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-huntington-disease-treatment","link_type":"mentions","strength":0.5,"evidence":"Entity 'HUNTINGTON' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-astrocyte-modulation-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-astrocyte-metabolic-modulation-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-astrocyte-neuron-metabolic-coupling-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-eaat2-glutamate-buffer-rescue","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-eeat2-glutamate-buffer-rescue","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-astrocyte-neuron-reprogramming","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-astrocyte-therapeutics-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocyte-precursor-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-senescence-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-reactivity-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-iron-alpha-synuclein-pathology","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-reactivity","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-neuron-metabolic-coupling","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-metabolic-enhancement-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-astrocyte-exosomal-mrna-reference-genes","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-astrocyte-pd-therapy-companies","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-astrocyte-targeted-parkinsons-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-astrocyte-ferritin-iron-metabolism-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-astrocyte-neuron-metabolic-coupling-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-exosome-based-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-mitochondrial-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-anti-amyloid-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-tgfb-signaling-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-neurotrophic-factor-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-anti-tau-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-microbiome-based-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-senolytic-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-er-stress-upr-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-adult-neurogenesis-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-4r-tauopathy-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-protein-aggregation-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-mitochondrial-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-heat-shock-protein-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-glp-1-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-rna-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-anti-tau-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-peptide-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-lysosomal-dysfunction-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-anti-amyloid-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-rna-editing-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-digital-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-events-mds-2026-parkinsons-emerging-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-4d-molecular-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-chelsea-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-ad-exosome-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-neubase-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-appvian-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-vator-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-alectos-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-sangamo-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-crispr-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-neuromito-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-inception-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-yumanity-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-monte-rosa-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-t3d-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-neuexo-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-cyclo-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-cynata-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-lyterian-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-denali-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-evox-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-cerevel-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-trefoil-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-pd-digital-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-pd-exosome-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-click-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-pd-rna-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-ventus-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-rodin-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-arvinas-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-pear-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-axsome-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-synaptic-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-synchronicity-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-ad-rna-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-encoded-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-axial-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-lexeo-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-vtv-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-neteo-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-stoke-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-heqix-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-karuna-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-fulcrum-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-iduna-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-lysoway-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-koneqia-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-ad-digital-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-ifm-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-voyager-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-alterity-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-pinteon-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-blue-rock-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-spark-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-muna-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-finch-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-aleza-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-prevail-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-paxos-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-capricor-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-sage-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-convelo-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-neumora-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-spin-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-amyl-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-cytochrome-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-brainstorm-cell-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-organizations-denali-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-denali-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-aleza-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'THERAPEUTICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-biomarker-guided-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-combination-therapy-biomarker-validation","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-biomarker-neuron-entities","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-biomarker-therapeutic-development-nexus","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-biomarker-discovery-framework","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-biomarker-classification-cbs","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-biomarker-overview","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-biomarker-guided-therapy-sequencing-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-er-stress-upr-modulator-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-er-stress-unfolded-protein-response","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbs-er-stress","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-er-stress-upr-psp","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-er-stress-upr-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-er-stress-upr-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbs-er-stress-upr","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-er-stress-upr-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-er-stress-upr-disease-comparison","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbd-er-stress-upr","link_type":"mentions","strength":0.5,"evidence":"Entity 'ER STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-mitophagy-activators","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOPHAGY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-mitophagy-enhancer-prophylaxis","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOPHAGY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-mitophagy-gate-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOPHAGY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitophagy-pathway-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOPHAGY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitophagy","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOPHAGY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitophagy-defect","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOPHAGY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitophagy-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOPHAGY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitophagy-receptor-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOPHAGY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-blarcamesine-axon","link_type":"mentions","strength":0.5,"evidence":"Entity 'AXON' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-trap-ad-nct04784416","link_type":"mentions","strength":0.5,"evidence":"Entity 'TRAP' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-blood-flow-restriction-pd-balance-nct06508801","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-bfr-balance-pd-nct06508801","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-bbb-penetration-technologies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-blood-brain-barrier-transport-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-blood-brain-barrier-endothelial-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-ptau217-onset-timing-clock","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-breakdown-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier-breakdown-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-based-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-breakdown-disease-driver","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-dysfunction-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier-dysfunction","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-dysfunction-vascular-ci","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier-biology","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-dysfunction-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bbb-crossing","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-ptau217-onset-timing-clock","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-microbial-signatures-parkinson","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-ptau-systemic-amyloidosis","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-based-biomarkers-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-biomarkers-atypical-parkinsonism","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-bbb-integrity-cbs","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-blood-brain-barrier-cbs","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-blood-biomarkers-atypical-parkinsonism","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-blood-biomarker-ad-detection","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-blood-brain-barrier-aging-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-blood-biomarker-vs-tau-pet-monitoring","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-events-aaic-2026-biomarker-integration-blood-biomarkers-validation","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-biomarkers-parkinsonian-syndromes-nct06501469","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKERS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-biomarkers-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKERS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-biomarkers-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKERS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-biomarkers-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKERS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-ftld-tau-tdp-distinction","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKERS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-corticobasal-degeneration-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKERS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-multiple-system-atrophy-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKERS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-progressive-supranuclear-psp-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKERS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-pink1-protein","link_type":"mentions","strength":0.5,"evidence":"Entity 'PINK1' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-parkin-protein","link_type":"mentions","strength":0.5,"evidence":"Entity 'PARKIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-sod1-protein","link_type":"mentions","strength":0.5,"evidence":"Entity 'SOD1' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-plor","link_type":"mentions","strength":0.5,"evidence":"Entity 'PLOR' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-disc1","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISC1' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-mlcs-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-mitochondria-lysosome-contact-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-mlsm-axis-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mlcs-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitochondria-lysosome-contact-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitochondria-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitochondria-lysosome-contact-sites","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-mitochondria","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-stress-granule-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-stress-granule-modulation-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-stress-granules-rnp","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-stress-granule-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-stress-granule-neuron","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granule-rna-granules","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granules-in-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-response-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granule-dynamics","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granules-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granules","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granule-disease-comparison","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granule-dysfunction-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-stress-granule-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-circuits-alzheimer-hippocampal-circuit","link_type":"mentions","strength":0.5,"evidence":"Entity 'ALZHEIMER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-alzheimer-europe","link_type":"mentions","strength":0.5,"evidence":"Entity 'ALZHEIMER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-alzheimer-indonesia","link_type":"mentions","strength":0.5,"evidence":"Entity 'ALZHEIMER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-circuits-parkinson-basal-ganglia-circuit","link_type":"mentions","strength":0.5,"evidence":"Entity 'PARKINSON' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-synapse-resilience-bdnf-glymphatic","link_type":"mentions","strength":0.5,"evidence":"Entity 'SYNAPSE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-synapse-elimination-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'SYNAPSE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-neurodegeneration-parkinson","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dementia-with-lewy-bodies-astrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-argyrophilic-grain-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-hepatic-encephalopathy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-homeostasis","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-als","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-wilson-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-astrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dentatorubral-pallidoluysian-atrophy-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-wilson-disease-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-neurons-hierarchy","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-normal-pressure-hydrocephalus-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-prion-disease-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-lysosomal-storage-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-spinocerebellar-ataxia-type-3-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-viral-entry-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-bipolar-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIPOLAR' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-bipolar-cells-visual-processing","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIPOLAR' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-spinal-interneurons-motor-neuron-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cerebellar-purkinje-cells-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-cholinergic-neurons-in-lewy-body-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-neurons-lewy-body-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cerebellar-neurons-creutzfeldt-jakob-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cerebellar-granule-cells-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-ivns1abp-mutation-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cross-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cerebrovascular-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocytes-msa","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocytes-multiple-system-atrophy","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocytes-adrenoleukodystrophy","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocytes-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-multiple-system-atrophy-oligodendrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocytes-myelination","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-oligodendrocytes-myelinating","link_type":"mentions","strength":0.5,"evidence":"Entity 'OLIGODENDROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-aging-associated-astrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-aging-oligodendrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-aging-microglia","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-aging-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-aging-to-ad-switch-trigger","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cardiac-intrinsic-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'CARDIAC' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-cardiac-mibg-scan","link_type":"mentions","strength":0.5,"evidence":"Entity 'CARDIAC' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-protein-aggregation","link_type":"mentions","strength":0.5,"evidence":"Entity 'PROTEIN AGGREGATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-protein-aggregation-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'PROTEIN AGGREGATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-protein-aggregation-disease-comparison","link_type":"mentions","strength":0.5,"evidence":"Entity 'PROTEIN AGGREGATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-ad-neuroinflammation-microglia-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbs-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbd-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-pd-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-cbs-psp-neuroinflammation-pet","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-liver-brain-neurodegeneration-axis","link_type":"mentions","strength":0.5,"evidence":"Entity 'LIVER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-liver-brain-axis-bbb-protection","link_type":"mentions","strength":0.5,"evidence":"Entity 'LIVER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-lxr-signaling-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'LIVER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIAL DYNAMICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIAL DYNAMICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-mitochondrial-dynamics","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIAL DYNAMICS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-neuron-specific-enolase-nse","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURON' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-neuron-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURON' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diseases-nbia","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mpan","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-india-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pla2g6-associated-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-bpan","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-japan-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-european-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-economic-burden-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-global-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-neurodegeneration-impact-measures","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pantothenate-kinase-associated-neurodegeneration-pkan","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-china-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-disease-progression","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-sleep-disorders-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pkan","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mitochondrial-dysfunction-neurodegeneration-comparison","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-familial-vs-sporadic-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mitochondrial-neurodegeneration-comparison","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-daly-methodology-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-us-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-manganism","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-clinical-trials-beacon-study-nct03860857","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-clinical-trials-olfactory-mucosa-early-neurodegeneration-nct06846658","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-clinical-trials-gut-brain-axis-neurodegeneration-nct05934188","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-clinical-trials-swedish-biofinder-2-psp-nct03174938","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-proteins-miro2-protein","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: RHOT1"},{"source_artifact_id":"wiki-proteins-miro1-protein","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: RHOT1"},{"source_artifact_id":"wiki-proteins-perk","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: RHOT1"},{"source_artifact_id":"wiki-proteins-chop","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: RHOT1"},{"source_artifact_id":"wiki-genes-miro2","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: RHOT1"},{"source_artifact_id":"wiki-mechanisms-tunneling-nanotubes","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: RHOT1"},{"source_artifact_id":"wiki-proteins-abcd3","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ABCD3 → RHOT1"},{"source_artifact_id":"wiki-mechanisms-actin-cytoskeleton-dynamics","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ACTIN → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-riluzole-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-lithium-continuation-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-nimodipine-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-d-cycloserine-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-lithium-carbonate-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-vitamins-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-idebenone-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-sargramostim-gm-csf-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-immunoglobulin-ivig-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-edaravone-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-naltrexone-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-sodium-phenylbutyrate-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-masitinib-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-amiloride-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-creatine-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-gabapentin-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-tauraso-nimodipine-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-clinical-trials-atl1103-antisense-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-cell-types-gabaergic-interneurons-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-cell-types-oculomotor-neurons-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-cell-types-upper-motor-neurons-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-cell-types-spinal-cord-neurons-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-cell-types-motor-cortex-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-cell-types-betz-cells-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-cell-types-spinal-cord-motor-neurons-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-cell-types-spinal-motor-neurons-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-mechanisms-viral-post-infectious-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-mechanisms-epigenetics-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-gaps-als-trial-failures","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-experiments-microbiome-gut-barrier-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-experiments-sleep-respiratory-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-experiments-environmental-exposure-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-institutions-healey-center-als","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALS → RHOT1"},{"source_artifact_id":"wiki-genes-kif24","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif27","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-dync2h1","link_type":"related","strength":0.5,"evidence":"Wiki title word 'DYNEIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif22","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif20b","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif26b","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif1b","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif17","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif25","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif9","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif3c","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif26a","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-genes-kif20a","link_type":"related","strength":0.5,"evidence":"Wiki title word 'KINESIN' found in hypothesis pathway"},{"source_artifact_id":"wiki-diseases-als","link_type":"related","strength":0.5,"evidence":"KG edge: diseases-als --activates--> RHOT1 (hypothesis target)"},{"source_artifact_id":"wiki-cell-types-hippocampal-ca3-neurons-alzheimer","link_type":"related","strength":0.5,"evidence":"KG edge: cell-types-hippocampal-ca3-neurons-alzheimer --activates--> RHOT1 (hypothesis target)"},{"source_artifact_id":"wiki-cell-types-microglia-neurodegeneration-alzheimer","link_type":"related","strength":0.5,"evidence":"KG edge: cell-types-microglia-neurodegeneration-alzheimer --activates--> RHOT1 (hypothesis target)"},{"source_artifact_id":"wiki-researchers-alois-alzheimer","link_type":"related","strength":0.5,"evidence":"KG edge: researchers-alois-alzheimer --activates--> RHOT1 (hypothesis target)"},{"source_artifact_id":"wiki-mechanisms-apoptosis","link_type":"related","strength":0.5,"evidence":"KG edge: mechanisms-apoptosis --activates--> RHOT1 (hypothesis target)"},{"source_artifact_id":"wiki-mechanisms-axonal-transport","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-alpers-huttenlocher-syndrome-mtdna-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-abca7-lipid-transport-microglial-phagocytosis-ad-causal-chain","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-axonal-transport-4r-tauopathies","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-electron-transport-chain","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-axonal-transport-dysfunction-comparison","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-axonal-transport-defects","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-nucleocytoplasmic-transport-defects","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-dynein","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-axonal-transport-pd-validation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-axonal-transport-psp","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-nucleocytoplasmic-transport-4r-tauopathies","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-exercise-bdnf-mitophagy-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-trans-synaptic-spread-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-retrograde-transport-endosomal-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-glutamate-transport","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-mlcs-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-metal-ion-synuclein-mitochondria-axis","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-mitochondria-lysosome-contact-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-nucleocytoplasmic-transport-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-mtdna-mutations-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-retrograde-axonal-transport-dysfunction","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-glymphatic-transport-optic-nerve","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-neuroinflammation-mitochondria-crosstalk","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-mitochondria-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-cbs-axonal-transport","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-mitochondria-lysosome-contact-sites","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-cytoskeletal-dynamics-axonal-transport","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-mechanisms-bbb-transport-mechanisms","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Miro1/TRAK kinesin-dynein mitochondrial transport"},{"source_artifact_id":"wiki-cell-types-telencephalon-development","link_type":"related","strength":0.55,"evidence":"Cell type Telencephalon Development mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-spinal-motoneurons-sma","link_type":"related","strength":0.55,"evidence":"Cell type spinal-motoneurons-sma mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-supraoptic-vasopressin-neurons-neurodegeneration","link_type":"related","strength":0.55,"evidence":"Cell type Supraoptic Vasopressin Neurons Neurodegeneration mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-spinal-cord-interneurons-chronic-pain","link_type":"related","strength":0.55,"evidence":"Cell type spinal-cord-interneurons-chronic-pain mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-hypothalamic-melanocortin-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Hypothalamic Melanocortin Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-hippocampal-ca3-pyramidal-neurons-parkinsons","link_type":"related","strength":0.55,"evidence":"Cell type hippocampal-ca3-pyramidal-neurons-parkinsons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-psd95-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Psd95 Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-subicular-neurons","link_type":"related","strength":0.55,"evidence":"Cell type subicular-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-spinothalamic-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Spinothalamic Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-cannabinoid-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Cannabinoid Receptor Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-adenosine-a3-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Adenosine A3 Receptor Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-layer-3-neurons","link_type":"related","strength":0.55,"evidence":"Cell type layer-3-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-claustrum-in-alzheimers-disease","link_type":"related","strength":0.55,"evidence":"Cell type Claustrum-in-Alzheimers-Disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-dopa-decarboxylase-neurons","link_type":"related","strength":0.55,"evidence":"Cell type dopa-decarboxylase-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-vasopressin-v1a-neurons","link_type":"related","strength":0.55,"evidence":"Cell type vasopressin-v1a-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-medium-spiny-neurons-huntington-disease","link_type":"related","strength":0.55,"evidence":"Cell type medium-spiny-neurons-huntington-disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-acc-chronic-pain","link_type":"related","strength":0.55,"evidence":"Cell type acc-chronic-pain mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-pituitary-somatotrophs-neurodegeneration","link_type":"related","strength":0.55,"evidence":"Cell type Pituitary Somatotrophs Neurodegeneration mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-interpeduncular-nucleus-in-parkinsons-disease","link_type":"related","strength":0.55,"evidence":"Cell type Interpeduncular-Nucleus-in-Parkinsons-Disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-histamine-h3-heteroreceptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type histamine-h3-heteroreceptor-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-myelin-forming-cells","link_type":"related","strength":0.55,"evidence":"Cell type myelin-forming-cells mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-glutamate-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Glutamate Receptor Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-dopamine-d1-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type dopamine-d1-receptor-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-blood-brain-barrier-endothelial-cells","link_type":"related","strength":0.55,"evidence":"Cell type blood-brain-barrier-endothelial-cells mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-catecholaminergic-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Catecholaminergic Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-arterial-endothelial-cells-brain","link_type":"related","strength":0.55,"evidence":"Cell type arterial-endothelial-cells-brain mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-voltage-gated-calcium-channel-neurons","link_type":"related","strength":0.55,"evidence":"Cell type voltage-gated-calcium-channel-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-choroid-plexus-in-alzheimers-disease","link_type":"related","strength":0.55,"evidence":"Cell type Choroid-Plexus-in-Alzheimers-Disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-retinal-amacrine-cells-parkinsons-disease","link_type":"related","strength":0.55,"evidence":"Cell type retinal-amacrine-cells-parkinsons-disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-sigma-1-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type sigma-1-receptor-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-serotonergic-raphe-neurons","link_type":"related","strength":0.55,"evidence":"Cell type serotonergic-raphe-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-adult-neural-stem-cells","link_type":"related","strength":0.55,"evidence":"Cell type adult-neural-stem-cells mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-npy-y1-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Npy Y1 Receptor Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-deep-cerebellar-nuclei-in-ataxia","link_type":"related","strength":0.55,"evidence":"Cell type Deep-Cerebellar-Nuclei-in-Ataxia mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-nucleus-incertus-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Nucleus Incertus Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-circadian-neurons-in-neurodegeneration","link_type":"related","strength":0.55,"evidence":"Cell type Circadian-Neurons-in-Neurodegeneration mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-lateral-hypothalamus","link_type":"related","strength":0.55,"evidence":"Cell type Lateral Hypothalamus mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-enteric-nervous-system-expanded","link_type":"related","strength":0.55,"evidence":"Cell type enteric-nervous-system-expanded mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-tyrosine-hydroxylase-th-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Tyrosine Hydroxylase Th Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-pontine-nucleus-neurons","link_type":"related","strength":0.55,"evidence":"Cell type pontine-nucleus-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-cerebellar-granule-cells","link_type":"related","strength":0.55,"evidence":"Cell type Cerebellar Granule Cells mentioned in hypothesis"},{"source_artifact_id":"wiki-diseases-economic-burden-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pantothenate-kinase-associated-neurodegeneration-pkan","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-global-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-india-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-japan-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mitochondrial-dysfunction-neurodegeneration-comparison","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-european-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mitochondrial-neurodegeneration-comparison","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-us-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pla2g6-associated-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mpan","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-daly-methodology-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-china-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-sleep-disorders-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-institutions-biogen","link_type":"mentions","strength":0.65,"evidence":"Title match: Biogen"},{"source_artifact_id":"wiki-diseases-familial-vs-sporadic-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-diseases-bpan","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-diseases-nbia","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier","link_type":"mentions","strength":0.65,"evidence":"Title match: Blood-Brain Barrier"},{"source_artifact_id":"wiki-diseases-pkan","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-diseases-stroke","link_type":"mentions","strength":0.65,"evidence":"Title match: Stroke"},{"source_artifact_id":"wiki-entities-oligodendrocytes","link_type":"mentions","strength":0.65,"evidence":"Title match: Oligodendrocytes"},{"source_artifact_id":"wiki-cell-types-blood-brain-barrier","link_type":"mentions","strength":0.65,"evidence":"Title match: Blood-Brain Barrier"},{"source_artifact_id":"wiki-therapeutics-levodopa","link_type":"mentions","strength":0.65,"evidence":"Title match: levodopa"},{"source_artifact_id":"wiki-diseases-parkinsons-disease","link_type":"mentions","strength":0.65,"evidence":"Title match: Parkinson's Disease"},{"source_artifact_id":"wiki-proteins-kinesin-1a-protein","link_type":"mentions","strength":0.65,"evidence":"Title match: Kinesin-1 Heavy Chain"},{"source_artifact_id":"wiki-diseases-amyotrophic-lateral-sclerosis","link_type":"mentions","strength":0.65,"evidence":"Title match: Amyotrophic Lateral Sclerosis"},{"source_artifact_id":"wiki-diseases-neurodegeneration-impact-measures","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-diseases-alzheimers-disease","link_type":"mentions","strength":0.65,"evidence":"Title match: Alzheimer's Disease"},{"source_artifact_id":"wiki-diseases-huntingtons","link_type":"mentions","strength":0.65,"evidence":"Title match: Huntington's Disease"},{"source_artifact_id":"wiki-diseases-disease-progression","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-companies","link_type":"mentions","strength":0.65,"evidence":"Title match: Companies"},{"source_artifact_id":"wiki-diseases-manganism","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-diseases-als","link_type":"mentions","strength":0.65,"evidence":"Title match: Amyotrophic Lateral Sclerosis (ALS)"},{"source_artifact_id":"wiki-therapeutics-riluzole","link_type":"mentions","strength":0.65,"evidence":"Title match: riluzole"},{"source_artifact_id":"wiki-companies-biogen","link_type":"mentions","strength":0.65,"evidence":"Title match: Biogen"},{"source_artifact_id":"open_question-587028fd-0a1e-4128-9aa8-12103c709890","link_type":"candidate_answer","strength":0.88,"evidence":"{\"confidence\": 0.88, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"source_artifact_id":"open_question-1d826b32-8dd0-49f5-a5c8-ed8ba7f20332","link_type":"bears_on_question","strength":0.5,"evidence":"{\"confidence\": 0.5, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"}],"current_artifact_id":"hypothesis-h-91bdb9ad","is_canonical":true,"supersede_chain":["hypothesis-h-91bdb9ad"]}