{"artifact":{"id":"hypothesis-h-a4e259e0","artifact_type":"hypothesis","entity_ids":"[\"CHRNA7\"]","title":"Enhancing Vagal Cholinergic Signaling to Restore Gut-Brain Anti-Inflammatory Communication","quality_score":0.6599999999999999,"created_by":"import","provenance_chain":null,"content_hash":"a4f18dd7f60381a5b0d5c1a6cb86ccaf61611b5657691f4cf04cf8cec02e8725","metadata":{"status":"proposed","disease":"neurodegeneration","analysis_id":"SDA-2026-04-01-gap-20260401-225149","target_gene":"CHRNA7","target_pathway":null,"_schema_version":1,"composite_score":0.6599999999999999},"created_at":"2026-04-02T20:53:40-07:00","updated_at":"2026-04-02T16:29:15.351115-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T20:53:40-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"646cc69d-88b8-4075-94d0-621ff4129d83","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"import"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"experiment-exp-5c1d023e-bee4-43c9-86c7-6cfdd411c9d3","link_type":"related","strength":0.6,"evidence":"Both artifacts share KG entity: 'chrna7'"},{"target_artifact_id":"experiment-exp-9bfa0f7a-eb9f-48b8-a324-82bd2e0143c6","link_type":"related","strength":0.6,"evidence":"Both artifacts share KG entity: 'chrna7'"},{"target_artifact_id":"experiment-exp-d8bfd8d9-639f-433e-9e74-25587b83e81f","link_type":"related","strength":0.6,"evidence":"Both artifacts share KG entity: 'chrna7'"},{"target_artifact_id":"wiki-proteins-chrna7-protein","link_type":"related","strength":0.54,"evidence":"Reverse: Entity name match: CHRNA7"},{"target_artifact_id":"wiki-genes-slc22a1","link_type":"related","strength":0.54,"evidence":"Reverse: KG edge: SLC22A1 connects to CHRNA7"},{"target_artifact_id":"wiki-genes-gnal","link_type":"related","strength":0.54,"evidence":"Reverse: Wiki page 'GNAL — Gαolf Subunit' — entity matches hypothesis target"},{"target_artifact_id":"wiki-genes-rest","link_type":"related","strength":0.54,"evidence":"Reverse: Wiki page 'REST Gene' — entity matches hypothesis target"},{"target_artifact_id":"wiki-diseases-nbia","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-mpan","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-india-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-pla2g6-associated-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-bpan","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-japan-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-european-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-economic-burden-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-global-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-neurodegeneration-impact-measures","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-pantothenate-kinase-associated-neurodegeneration-pkan","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-china-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-disease-progression","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-sleep-disorders-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-pkan","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-mitochondrial-dysfunction-neurodegeneration-comparison","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-familial-vs-sporadic-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-mitochondrial-neurodegeneration-comparison","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-daly-methodology-neurodegeneration","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-us-neurodegeneration-epidemiology","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-diseases-manganism","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-clinical-trials-beacon-study-nct03860857","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-clinical-trials-olfactory-mucosa-early-neurodegeneration-nct06846658","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-clinical-trials-gut-brain-axis-neurodegeneration-nct05934188","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-clinical-trials-swedish-biofinder-2-psp-nct03174938","link_type":"related","strength":0.54,"evidence":"Reverse: Disease page related to hypothesis disease: neurodegeneration"},{"target_artifact_id":"wiki-proteins","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-clinical-trials-varenicline-falls-pd-nct06679374","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-proteins-ric3-protein","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-proteins-chrna2-protein","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-genes-chrnb1","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-genes-chat","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-genes-chrnb3","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-genes-ddc","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-cell-types-paratenial-nucleus","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-cell-types-laterodorsal-tegmental-cholinergic","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-cell-types-cholinergic-neurons-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-cell-types-striatal-cholinergic-interneurons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"wiki-mechanisms-pink1-parkin-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ftd-tdp43-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tau-seeding-propagation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-atp13a2-lysosomal-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dat-dysfunction-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-igf-1-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dopaminergic-neuron-vulnerability","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-trace-amine-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ceramide-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mesolimbic-dopamine-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-alpers-huttenlocher-syndrome-mtdna-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-reactive-oxygen-species","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gaucher-disease-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-autosis-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nlrp3-inflammasome-ad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gba-glucocerebrosidase-endolysosomal-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mitochondrial-quality-control-network-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ampk-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mapk-erk-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-park2-parkin-ubiquitin-ligase-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hypoxia-response","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ras-mapk-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nfkb-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-huntingtons-disease-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-astrocyte-senescence-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nurr1-nr4a2-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-intrinsic-apoptosis-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-sporadic-alzheimers-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gdnf-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-vps35-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-htt-transcriptional-dysregulation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-zinc-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-brain-reserve-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tdp43-rna-granule-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hippo-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-oligodendrocyte-dysfunction-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-wnt-beta-catenin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-fa2h-associated-neurodegeneration-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-protein-o-glcna-cylation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-frontotemporal-dementia-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ad-neuroinflammation-microglia-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-protein-kinase-c-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pkr-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-synaptic-loss-ad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-lrrk2-pathway-parkinson-disease","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-apoe-lipid-metabolism-alzheimers","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neurovascular-ad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nrf2-oxidative-stress","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-noradrenergic-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mitophagy-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glucocorticoid-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-oligodendrocyte-dysfunction-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-lrrk2-kinase-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-s100-protein-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tgf-beta-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pallido-thalamocortical-motor-pathway-pd","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nrf2-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-vascular-dementia-mechanism-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hedgehog-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-endolysosomal-pathway-alzheimers","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-braak-staging-tau-propagation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-il-1-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-synuclein-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cortisol-tau-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-prion-disease-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pkan-neurodegeneration-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-amyloid-beta-cellular-uptake-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-progesterone-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-vagus-nerve-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-multiple-system-atrophy-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-synaptic-dysfunction-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-autophagy-lysosomal-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mtor-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neuroimmune-interface","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-bace1-amyloidogenic-cleavage-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cbs-autophagy-lysosomal-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dementia-lewy-bodies-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-microglial-priming-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-jak-stat-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-alpha-synuclein-propagation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-down-syndrome-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glycosaminoglycan-metabolism","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tau-pathology-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hippo-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ghrelin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-camkii-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-als-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-synaptic-loss-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-p-body-processing-bodies-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-traumatic-brain-injury-neurodegeneration-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dopamine-metabolism","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-er-stress-unfolded-protein-response","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cerebral-amyloid-angiopathy-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-lrrk2-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-calcium-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-retinal-degeneration-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-ad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hexosamine-biosynthetic-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-endosomal-lysosomal-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-endothelin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-brain-volume-changes-ad","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ppar-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-s1p-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-trem2-amyloid-clearance-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gba-glucocerebrosidase-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pallido-thalamocortical-motor-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-amyloid-beta-trans-synaptic-spread-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-rage-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pyroptosis-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-bdnf-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-notch-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-alpha-synuclein-aggregation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-trem2-cytokine-regulation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tgf-beta-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-endosomal-trafficking","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pink1-parkin-mitophagy-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-synaptic-vesicle-cycling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cgmp-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nlrp3-inflammasome-activation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cgas-sting-cytosolic-dna-sensing-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-slit-robo-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-protein-oligomerization-toxicity-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dj1-oxidative-stress-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-heat-shock-protein-response-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-amyloid-cascade-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neuroinflammation-microglia-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-notch-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-normal-pressure-hydrocephalus-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gdnf-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-brain-region-therapeutic-targeting-index","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ftd-tau-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-leptin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-vps35-retromer-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cntf-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-trem2-microglial-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-androgen-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-fgf-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hippo-signaling-parkinsons-disease","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-focal-adhesion-kinase-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-protein-sumoylation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-oxidative-stress-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-peroxisome-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ferroptosis-neurodegeneration-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-adiponectin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-apoptosis","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-retrograde-transport-endosomal-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-rem-sleep-behavior-disorder-neurodegeneration-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-erythropoietin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ferroptosis-ad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-psp-central-vestibular-pathway-vulnerability","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-vegf-angiogenesis-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-histamine-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-sirtuin-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nlrp3-inflammasome-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-necroptosis","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-melatonin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-semaphorin-plexin-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neuroinflammation-ad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dyrk1a-tau-phosphorylation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tgf-beta-bmp-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ferroptosis-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-orexin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-foxo-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tau-phosphorylation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cerebellar-degeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nf-kappa-b-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glymphatic-system-dysfunction","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-lipophagy-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-p75ntr-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dopamine-biosynthesis-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nad-metabolism-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-huntingtin-proteolysis-cleavage-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-kynurenine-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-serotonin-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-p70s6k-mtorc1-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-bdnf-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-somatostatin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cbd-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ephrin-ephr-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-peroxisome-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-synaptic-spine-degradation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-kynurenine-4r-tauopathies","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-autophagic-cell-death-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ceramide-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-uchl1-park5-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-vascular-cognitive-impairment-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hydrogen-sulfide-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-membrane-trafficking-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tlr-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ubiquitin-proteasome-ad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-brain-endothelial-cell-dysfunction-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-4r-tauopathies-brain-region-vulnerability","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-chemokine-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-integrin-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pd-lrrk2-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-fusion-fission","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-wnt-beta-catenin-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-excitotoxicity-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dopamine-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-stroke-neurodegeneration-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-calcium-excitotoxicity-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-amyloid-beta-oligomerization-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pd-synaptic-vesicle-trafficking-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-rna-toxicity","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neuroinflammation-mitochondria-crosstalk","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-calcineurin-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-jnk-p38-mapk-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-anti-amyloid-therapeutics","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gdnf-neurotrophic-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-er-stress-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mark-tau-phosphorylation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-vitamin-d-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-jak-stat-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-lewy-body-formation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gba-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-multiple-sclerosis-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mitophagy-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mitophagy-receptor-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-serotonin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-white-matter-lesion-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-transcription-regulation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-golgi-apparatus-dysfunction","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-lrrk2-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mutant-huntingtin-aggregation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-er-stress-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neuronal-network-dysfunction-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-camp-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nrf2-keap1-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neurotrophic-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-als-sod1-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-brain-insulin-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-metabolic-dysfunction-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gdnf-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-ephrin-ephr-receptor-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mirna-regulation-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nt-3-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cgas-sting-ad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pi3k-akt-mtor-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-proteasomal-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mapk-erk-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-netrin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-notch-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gaba-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-niemann-pick-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glucocorticoid-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-lrrk2-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-infantile-neuroaxonal-dystrophy-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tanycytes-tau-clearance","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glutamate-excitotoxicity-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-msa-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-sestrin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-autophagy-lysosomal-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-polyamine-metabolism-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-insulin-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-angiogenesis","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-fabry-disease-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-als-c9orf72-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cxcl12-cxcr4-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hydrogen-peroxide-metabolism","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-wnt-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nt-4-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-thyroid-hormone-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tfeb-autophagy-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-yap-taz-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-p53-parkinson-disease","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-autophagy-lysosome-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tnf-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cerebral-ischemia-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-natriuretic-peptide-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-huntington-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-amyloid-cascade","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gabaergic-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-autophagy-lysosome-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pd-neuroinflammation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cytoskeletal-dynamics-axonal-transport","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-akt-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neuropeptide-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dj1-park7-neuroprotection-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-park7-dj1-neuroprotection-pd-causal-chain","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-brain-age-gap-amyloid-ad","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cgas-sting-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cell-cycle-re-entry-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-insulin-signaling-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glutathione-metabolism","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-wilsons-disease-copper-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-peroxisome-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-rna-metabolism-dysregulation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-microglial-senescence-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-pp2a-tau-phosphatase-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-alpha-synuclein-aggregation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-il-6-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-app-amyloid-pathway-alzheimers","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nlrp3-inflammasome-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gdf-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-gsk3-beta-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-sting-casm-gabarap-lrrk2-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-synaptic-plasticity","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-viral-involvement-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-lysosomal-storage-disorders-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-synaptic-vesicle-trafficking-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-hsp70-hsp90-chaperone-pathway-parkinsons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-astrocyte-neuron-metabolic-coupling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-amyloid-beta-fibril-formation-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-atp13a2-park9-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-nfkb-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-complement-system-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dna-damage-response","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-protein-synthesis","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cgas-sting-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dopamine-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-mtor-signaling-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-sphingolipid-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-sirt1-alzheimer-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tyrobp-dap12-microglia-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-dlb-autonomic-dysfunction-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-otulin-tau-regulation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-oligodendrocyte-neuron-metabolic-support","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-neuroimmune-checkpoint-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glutamatergic-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-necroptosis-pathway-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-c9orf72-hexanucleotide-repeat-expansion-als-ftd","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-als-superoxide-dismutase-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-circadian-clock-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-trem2-microglia-pathway-alzheimers","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-bbb-dysfunction-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glp-1-signaling-neurodegeneration","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-cgas-sting-autophagy","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-proteostasis-erad-pathway","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-fus-proteinopathy-pathway-als","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-tau-seeding-propagation","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-glutamate-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-norepinephrine-signaling","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-mechanisms-autophagy-lysosomal-cbs","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"target_artifact_id":"wiki-cell-types-dopaminergic-neurons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Dopaminergic Neurons"},{"target_artifact_id":"wiki-mechanisms-alpha-synuclein-pathology","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Alpha-Synuclein Pathology"},{"target_artifact_id":"wiki-cell-types-vagal-afferent-neurons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Vagal Afferent Neurons"},{"target_artifact_id":"wiki-brain-regions-brainstem","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Brainstem"},{"target_artifact_id":"wiki-mechanisms-blood-brain-barrier","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Blood-Brain Barrier"},{"target_artifact_id":"wiki-diseases-stroke","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Stroke"},{"target_artifact_id":"wiki-clinical-trials","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Clinical Trials"},{"target_artifact_id":"wiki-cell-types-blood-brain-barrier","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Blood-Brain Barrier"},{"target_artifact_id":"wiki-brain-regions-dorsal-motor-nucleus-vagus","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Dorsal Motor Nucleus of the Vagus"},{"target_artifact_id":"wiki-entities-microbiome","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Microbiome"},{"target_artifact_id":"wiki-cell-types-dorsal-motor-nucleus-vagus","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Dorsal Motor Nucleus of the Vagus"},{"target_artifact_id":"wiki-cell-types-enteric-neurons","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Enteric Neurons"},{"target_artifact_id":"wiki-diseases-parkinsons-disease","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Parkinson's Disease"},{"target_artifact_id":"wiki-entities-nlrp3-inflammasome","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: NLRP3 Inflammasome"},{"target_artifact_id":"wiki-brain-regions","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Brain Regions"},{"target_artifact_id":"wiki-cell-types-endothelial-cells","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Endothelial Cells"},{"target_artifact_id":"wiki-diagnostics-neuroimaging","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: neuroimaging"},{"target_artifact_id":"wiki-diseases-vascular-dementia","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Vascular Dementia"},{"target_artifact_id":"wiki-cell-types-dorsal-motor-vagus","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Dorsal Motor Nucleus of the Vagus"},{"target_artifact_id":"wiki-proteins-alpha-synuclein","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: alpha-synuclein"},{"target_artifact_id":"wiki-ai-tool-alibaba-tongyi-qianwen-bio","link_type":"related","strength":0.7,"evidence":"disease: neurodegeneration"},{"target_artifact_id":"wiki-als","link_type":"related","strength":0.4,"evidence":"KG bridge: ALS ↔ CHRNA7"},{"target_artifact_id":"wiki-genes-chrna7","link_type":"related","strength":0.6,"evidence":null},{"target_artifact_id":"wiki-neurodegeneration","link_type":"related","strength":0.8,"evidence":"Hypothesis relates to disease described in wiki"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"derives_from","strength":0.95,"evidence":"Hypothesis derives from this analysis"},{"target_artifact_id":"wiki-genes-chrna7","link_type":"mentions","strength":0.9,"evidence":"Hypothesis targets gene CHRNA7"},{"target_artifact_id":"wiki-diseases-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Disease: neurodegeneration"},{"target_artifact_id":"wiki-genes-tlr4","link_type":"mentions","strength":0.5,"evidence":"Entity TLR4 in hypothesis text"},{"target_artifact_id":"wiki-genes-socs3","link_type":"mentions","strength":0.5,"evidence":"Entity SOCS3 in hypothesis text"},{"target_artifact_id":"wiki-proteins-nlrp3","link_type":"mentions","strength":0.5,"evidence":"Entity NLRP3 in hypothesis text"},{"target_artifact_id":"wiki-genes-hmgb1","link_type":"mentions","strength":0.5,"evidence":"Entity HMGB1 in hypothesis text"},{"target_artifact_id":"wiki-genes-nts","link_type":"mentions","strength":0.5,"evidence":"Entity NTS in hypothesis text"},{"target_artifact_id":"wiki-genes-akt1","link_type":"related","strength":0.4,"evidence":"KG bridge: AKT1 ↔ CHRNA7"},{"target_artifact_id":"wiki-genes-abcb1","link_type":"related","strength":0.4,"evidence":"KG bridge: ABCB1 ↔ CHRNA7"},{"target_artifact_id":"wiki-entities-acetylcholine","link_type":"related","strength":0.4,"evidence":"KG bridge: ACETYLCHOLINE ↔ CHRNA7"},{"target_artifact_id":"wiki-genes-ager","link_type":"related","strength":0.4,"evidence":"KG bridge: AGER ↔ CHRNA7"},{"target_artifact_id":"wiki-institutions-packard-center-als","link_type":"related","strength":0.4,"evidence":"KG bridge: ALS ↔ CHRNA7"},{"target_artifact_id":"wiki-institutions-alzheimer-indonesia","link_type":"related","strength":0.4,"evidence":"KG bridge: ALZHEIMER ↔ CHRNA7"},{"target_artifact_id":"wiki-diseases-alzheimers-disease","link_type":"related","strength":0.4,"evidence":"KG bridge: ALZHEIMER'S DISEASE ↔ CHRNA7"},{"target_artifact_id":"wiki-entities-aria-imaging","link_type":"related","strength":0.4,"evidence":"KG bridge: AMYLOID ↔ CHRNA7"},{"target_artifact_id":"wiki-hypotheses-apoe-contributes-alzheimers-disease-regulat","link_type":"related","strength":0.4,"evidence":"KG bridge: APOE ↔ CHRNA7"},{"target_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"related","strength":0.4,"evidence":"KG bridge: Aging ↔ CHRNA7"},{"target_artifact_id":"wiki-genes-chrna7","link_type":"targets","strength":0.9,"evidence":null},{"target_artifact_id":"wiki-clinical-trials-a4-study","link_type":"see_also","strength":0.5,"evidence":"Reverse: Wiki title word 'ANTI' found in hypothesis pathway"},{"target_artifact_id":"wiki-cell-types-hippocampal-ca3-neurons-alzheimer","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: cell-types-hippocampal-ca3-neurons-alzheimer --associated_with--> CHRNA7 (hypothesis target)"},{"target_artifact_id":"wiki-researchers-alois-alzheimer","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: researchers-alois-alzheimer --associated_with--> CHRNA7 (hypothesis target)"},{"target_artifact_id":"wiki-proteins-amyloid-beta","link_type":"see_also","strength":0.5,"evidence":"Reverse: KG edge: proteins-amyloid-beta --activates--> CHRNA7 (hypothesis target)"},{"target_artifact_id":"wiki-genes-chrna7","link_type":"see_also","strength":0.7,"evidence":"Hypothesis targets gene CHRNA7 discussed in wiki page"}],"incoming_links":[{"source_artifact_id":"experiment-exp-36adfa0c-75e6-4898-b4fd-ab95fa7beea6","link_type":"related","strength":0.3333333333333333,"evidence":null},{"source_artifact_id":"experiment-exp-5c1d023e-bee4-43c9-86c7-6cfdd411c9d3","link_type":"related","strength":1.0,"evidence":"Shared entity overlap (Jaccard=1.00)"},{"source_artifact_id":"experiment-exp-d8bfd8d9-639f-433e-9e74-25587b83e81f","link_type":"related","strength":1.0,"evidence":"Shared entity overlap (Jaccard=1.00)"},{"source_artifact_id":"experiment-exp-9bfa0f7a-eb9f-48b8-a324-82bd2e0143c6","link_type":"related","strength":1.0,"evidence":"Shared entity overlap (Jaccard=1.00)"},{"source_artifact_id":"wiki-therapeutics-vagus-nerve-stimulation","link_type":"mentions","strength":0.5,"evidence":"Content: CHRNA7 mentioned 2x in wiki/therapeutics-vagus-nerve-stimulation"},{"source_artifact_id":"wiki-cell-types-nicotinic-alpha7-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Content: CHRNA7 mentioned 2x in wiki/cell-types-nicotinic-alpha7-receptor-neurons"},{"source_artifact_id":"wiki-proteins-nes-protein","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-a4e259e0: ...cation](/hypothesis/h-a4e259e0) — <span style=\"col..."},{"source_artifact_id":"wiki-proteins-nf-l","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-a4e259e0: ...cation](/hypothesis/h-a4e259e0) — <span style=\"col..."},{"source_artifact_id":"wiki-proteins-prkn-protein","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-a4e259e0: ...cation](/hypothesis/h-a4e259e0) — <span style=\"col..."},{"source_artifact_id":"wiki-genes-nfl","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-a4e259e0: ...cation](/hypothesis/h-a4e259e0) — <span style=\"col..."},{"source_artifact_id":"wiki-ideas-biomarker-nfl-neuroprotection-threshold","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-a4e259e0: ...cation](/hypothesis/h-a4e259e0) — <span style=\"col..."},{"source_artifact_id":"wiki-biomarkers-neurofilament-light-chain-nfl","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-a4e259e0: ...cation](/hypothesis/h-a4e259e0) — <span style=\"col..."},{"source_artifact_id":"wiki-biomarkers-neurofilament-light-chain-blood-nfl","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-a4e259e0: ...cation](/hypothesis/h-a4e259e0) — <span style=\"col..."},{"source_artifact_id":"wiki-ai-tool-alibaba-tongyi-qianwen-bio","link_type":"related","strength":0.7,"evidence":"disease: neurodegeneration"},{"source_artifact_id":"wiki-als","link_type":"related","strength":0.4,"evidence":"KG bridge: ALS ↔ CHRNA7"},{"source_artifact_id":"wiki-mpan","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'mpan' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-chrna7","link_type":"mentions","strength":0.7,"evidence":null},{"source_artifact_id":"wiki-proteins-tlr4","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-genes-tlr4","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-entities-tlr4","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-proteins-chrna7-protein","link_type":"mentions","strength":0.6,"evidence":"Entity name match: CHRNA7"},{"source_artifact_id":"wiki-neurodegeneration","link_type":"related","strength":0.8,"evidence":"Wiki disease page related to hypothesis about neurodegeneration"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"derives_from","strength":0.95,"evidence":"Hypothesis generated from analysis debate"},{"source_artifact_id":"wiki-genes-tlr4","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'TLR4 Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-slc22a1","link_type":"related","strength":0.6,"evidence":"KG edge: SLC22A1 connects to CHRNA7"},{"source_artifact_id":"wiki-clinical-trials-varenicline-falls-pd-nct06679374","link_type":"related","strength":0.5,"evidence":"Gene 'CHRNA7' found in wiki content"},{"source_artifact_id":"wiki-genes-gnal","link_type":"mentions","strength":0.6,"evidence":"Wiki page 'GNAL — Gαolf Subunit' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-rest","link_type":"mentions","strength":0.6,"evidence":"Wiki page 'REST Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-alpha_synuclein_aggregation","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'alpha_synuclein_aggregation' — entity matches hypothesis target"},{"source_artifact_id":"wiki-amyloid_clearance","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'amyloid_clearance' — entity matches hypothesis target"},{"source_artifact_id":"wiki-dopaminergic_neuron_death","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'dopaminergic_neuron_death' — entity matches hypothesis target"},{"source_artifact_id":"wiki-mitochondrial_complex_I","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'mitochondrial_complex_I' — entity matches hypothesis target"},{"source_artifact_id":"wiki-mitochondrial_dysfunction","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'mitochondrial_dysfunction' — entity matches hypothesis target"},{"source_artifact_id":"wiki-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'neuroinflammation' — entity matches hypothesis target"},{"source_artifact_id":"wiki-phagocytosis","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'phagocytosis' — entity matches hypothesis target"},{"source_artifact_id":"wiki-acetylcholine","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'acetylcholine' — entity matches hypothesis target"},{"source_artifact_id":"wiki-late","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'late' — entity matches hypothesis target"},{"source_artifact_id":"wiki-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'neurodegeneration' — entity matches hypothesis target"},{"source_artifact_id":"wiki-stroke","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'stroke' — entity matches hypothesis target"},{"source_artifact_id":"wiki-MICROGLIA","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'MICROGLIA' — entity matches hypothesis target"},{"source_artifact_id":"wiki-microglia","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'microglia' — entity matches hypothesis target"},{"source_artifact_id":"wiki-alpha-synuclein","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'alpha-synuclein' — entity matches hypothesis target"},{"source_artifact_id":"wiki-mitochondria","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'mitochondria' — entity matches hypothesis target"},{"source_artifact_id":"wiki-projects","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Projects' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-lrp3","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'LRP3 Protein' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-parkin","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Parkin' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-tlr4","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Toll-Like Receptor 4 (TLR4)' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-rela","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'NF-κB p65 Protein' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-nlrp3","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'NLRP3 (NLR Family Pyrin Domain Containing 3)' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-nrf2","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'nrf2' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-lrp3","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'LRP3 — Low Density Lipoprotein Receptor-Related Protein 3' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-parkin","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'PARKIN Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-stat3","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'STAT3 Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-jak2","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'JAK2 Gene - Janus Kinase 2' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-rela","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'RELA (NF-κB p65)' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-syna","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'syna' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-gain","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'GAIN Gene - GABA-A Receptor Associated Protein Like 2' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-socs3","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'SOCS3 - Suppressor of Cytokine Signaling 3' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-hmgb1","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'HMGB1 — High Mobility Group Box 1' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes-nrf2","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'NRF2 Gene' — entity matches hypothesis target"},{"source_artifact_id":"wiki-mechanisms-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'neuroinflammation' — entity matches hypothesis target"},{"source_artifact_id":"wiki-diseases-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Neurodegeneration' — entity matches hypothesis target"},{"source_artifact_id":"wiki-companies","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'companies' — entity matches hypothesis target"},{"source_artifact_id":"wiki-genes","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Genes' — entity matches hypothesis target"},{"source_artifact_id":"wiki-models","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'Models' — entity matches hypothesis target"},{"source_artifact_id":"wiki-proteins-chrna7-protein","link_type":"related","strength":0.7,"evidence":"Wiki entity matches hypothesis target gene CHRNA7"},{"source_artifact_id":"wiki-genes-chrna7","link_type":"related","strength":0.7,"evidence":"Wiki entity matches hypothesis target gene CHRNA7"},{"source_artifact_id":"wiki-diseases-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-genes-nts","link_type":"mentions","strength":0.5,"evidence":"Entity NTS in hypothesis text"},{"source_artifact_id":"wiki-genes-abcb1","link_type":"related","strength":0.4,"evidence":"KG bridge: ABCB1 ↔ CHRNA7"},{"source_artifact_id":"wiki-entities-acetylcholine","link_type":"related","strength":0.4,"evidence":"KG bridge: ACETYLCHOLINE ↔ CHRNA7"},{"source_artifact_id":"wiki-genes-ager","link_type":"related","strength":0.4,"evidence":"KG bridge: AGER ↔ CHRNA7"},{"source_artifact_id":"wiki-genes-akt1","link_type":"related","strength":0.4,"evidence":"KG bridge: AKT1 ↔ CHRNA7"},{"source_artifact_id":"wiki-institutions-packard-center-als","link_type":"related","strength":0.4,"evidence":"KG bridge: ALS ↔ CHRNA7"},{"source_artifact_id":"wiki-institutions-alzheimer-indonesia","link_type":"related","strength":0.4,"evidence":"KG bridge: ALZHEIMER ↔ CHRNA7"},{"source_artifact_id":"wiki-diseases-alzheimers-disease","link_type":"related","strength":0.4,"evidence":"KG bridge: ALZHEIMER'S DISEASE ↔ CHRNA7"},{"source_artifact_id":"wiki-entities-aria-imaging","link_type":"related","strength":0.4,"evidence":"KG bridge: AMYLOID ↔ CHRNA7"},{"source_artifact_id":"wiki-hypotheses-apoe-contributes-alzheimers-disease-regulat","link_type":"related","strength":0.4,"evidence":"KG bridge: APOE ↔ CHRNA7"},{"source_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"related","strength":0.4,"evidence":"KG bridge: Aging ↔ CHRNA7"},{"source_artifact_id":"wiki-mechanisms-cholinergic-system-dysfunction-pathway","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions hypothesis target gene 'CHRNA7'"},{"source_artifact_id":"wiki-mechanisms-acetylcholine-signaling-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions hypothesis target gene 'CHRNA7'"},{"source_artifact_id":"wiki-genes-ddc","link_type":"related","strength":0.4,"evidence":null},{"source_artifact_id":"wiki-cell-types-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septal-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-neurons-dementia-lewy-bodies","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-pedunculopontine-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-mesopontine-cholinergic-tegmental-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-projection-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-projection","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-septal-nucleus-cholinergic-interneurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-225-advanced-speech-communication-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-vagal-motor-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-cholinergic-system-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-ldt-cholinergic-arousal","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-ldt-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-forebrain-bundle-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-cholinergic-system-dysfunction-pathway","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-striatal-interneurons-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-cholinergic-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-mesopontine-cholinergic-tegmentum","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-horizontal-diagonal-band-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septal-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septo-hippocampal-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic-alzheimers","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-ipsc-derived-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septum-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-section-209-advanced-cholinergic-system-therapy-cbs-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-ad","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-laterodorsal-tegmental-nucleus-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-ppn-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-dlb-cholinergic-dysfunction-mechanisms","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-septal-nuclei-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-cholinergic-signaling-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-cholinergic-neurod","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septa-hippocampal-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-vagal-afferent-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-locus-coeruleus-expanded-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-memory","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-ppn-cholinergic-psp","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-trochlear-nucleus-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-neurons-cognitive-decline","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-dorsal-vagal-nucleus-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-cholinergic-neurons-in-lewy-body-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-septal-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-ds","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-cholinergic-neurons-ppn","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-therapeutics-autophagy-enhancing-therapies","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-striatal-cholinergic-interneurons-huntingtons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-neurons-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-striatal-cholinergic-interneurons-in-parkinsons-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septo-hippocampal-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septo-hippocampal-cholinergic-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septal-cholinergic-expanded","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic-ad","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-ppn-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-cholinergic-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-neurons-in-alzheimers-disease","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-lewy-body","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-sepal-cholinergic-memory","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-basal-forebrain-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-cholinergic-degeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cholinergic-alzheimers","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-oculomotor-nucleus-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-parabrachial-nucleus-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-mesopontine-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-abducens-nucleus-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-alzheimers","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-interpeduncular-nucleus-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-neurons-brain","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cholinergic-expanded","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-neurons-apbd","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-cholinergic-system-degeneration-alzheimers","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-vertical-limb-diagonal-band-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-horizontal-limb-diagonal-band-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septal-cholinergic-memory","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-vertical-diagonal-band-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-septal-cholinergic-memory","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-ds-v2","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-laterodorsal-tegmental-nucleus-cholinergic-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-diagonal-band-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-striatal-cholinergic-interneurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-interpeduncular-nucleus-cholinergic-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-vagal-nucleus-parkinsons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-cholinergic-neurodegeneration","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-mesopontine-cholinergic-tegmental","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-meynert-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-laterodorsal-tegmental-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-mechanisms-cholinergic-hypothesis-ad","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-septal-nucleus-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-vertical-diagonal-band-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-basal-forebrain-cholinergic-expanded","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-dinger-westphal-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-septal-nuclei-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-basal-forebrain","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-basal-forebrain-alzheimers","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-horizontal-diagonal-band-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-dorsal-vagal-nucleus-msa","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-nucleus-meynert-cholinergic-neurons","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-cholinergic-interneurons-huntington","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-laterodorsal-tegmental-nucleus-cholinergic","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-cell-types-medial-septo-hippocampal-cholinergic-projection","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"source_artifact_id":"wiki-brain-connectivity-tacs-early-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-brain-computer-interface-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-brain-drug-delivery-challenges","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-brain-activity-walking-atypical-parkinsonism-nct06906276","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-brain-hyperconnectivity-tau-spread-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-brain-computer-interface","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-vascular-endothelial-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-organoids","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-capillary-endothelial-cells-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-endothelial-cells-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-endothelial-cells-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-venous-endothelial-cells-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-pericytes-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-endothelial-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-pericytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-ependymal-cells-brain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brain-pericytes-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-reserve-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-volume-changes-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-region-therapeutic-targeting-index","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-endothelial-cell-dysfunction-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-4r-tauopathies-brain-region-vulnerability","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-insulin-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-brain-age-gap-amyloid-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-multiple-system-atrophy","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-parkinsons-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-knowledge-platform","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-to-brain-interface","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-organoids","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-lewy-body-dementia","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-vascular-dementia","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-frontotemporal-dementia","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-progressive-supranuclear-palsy","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-corticobasal-degeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-shuttles","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-organoids-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-computer-interfaces","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-technology-landscape","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-computer-interface","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-als","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-index","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-normal-pressure-hydrocephalus","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-waste-clearance-therapies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-organoid-silicon-interface","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-brain-shuttle-technologies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bci-huntingtons-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-events-brain-health-roundtable-aadapt-act","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-brain-health-roundtable-aadapt-act","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-brain-insulin-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-connectivity","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-disease-involvement","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-vulnerability-map","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-brain-connectivity-tacs-early-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-brain-behavior-research-foundation","link_type":"mentions","strength":0.5,"evidence":"Entity 'BRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-complement-inhibitor-therapy-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-complement-c1q-inhibitor-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-complement-pathway-inhibition-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-complement-system-therapeutics-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-coagulation-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-system-activation-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-activation-cbd","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-mediated-synapse-loss","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-tauopathies-cbs","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-system-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-complement-system-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-complement-c3","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-gaps-complement-system-dysregulation-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'COMPLEMENT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-dopamine-agonists","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-dopamine-replacement-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-dopamine-agonists-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-msa","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d3-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-adhd","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d1-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d5-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-vta-dopamine-reward","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-fxtas","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d2-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-drd","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-transporter-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-d4-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dat-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-neurons-reward","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dopamine-transporter-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dat-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-pd-dopamine-metabolism","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-metabolism","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-biosynthesis-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-oxidation","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dopamine-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-dopamine","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-dopamine-d3-d4-selective-agonists","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-dopamine-metabolism-enzymes-beyond-comt","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-dopamine-transporter-modulators","link_type":"mentions","strength":0.5,"evidence":"Entity 'DOPAMINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-microglia-depletion-repopulation","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-microglia-modulation-therapies","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-microglia-modulation-therapy-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-microglia-state-editing-trem2-lxr","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-delivery-microglia-targeted-nanoparticles","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-microglia-state-editing-trem2-lxr","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nigral-microglia-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-neurodegeneration-alzheimer","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-nasu-hakola","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-batten-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-in-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-rasmussen","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-in-huntingtons-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-states","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-synapse-pruning","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-microglia-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-microglia-neuron-metabolic-crosstalk","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-microglia-corticobasal-degeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-microglia-ftd-progression","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-microglia-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-microglia-activation","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-microglia","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-microglia-in-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'MICROGLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-amyloid-vaccines","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-amyloid-plaque-neurofibrillary-tangle-depositi","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-amyloid-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-beta-exposed","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-beta-cortical-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-responsive-microglia","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-accumulating-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-amyloid-beta-exposed-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-cellular-uptake","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-tau-synergistic-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-conformational-strains","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-cellular-uptake-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-tau-synergistic-interaction-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-oligomers-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-trans-synaptic-spread-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-cascade-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-vs-tau-first","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-aggregation","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-clearance-therapeutic-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-oligomerization-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-cascade-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-fibril-formation","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-cascade","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-degradation-pathways","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-vs-tau-first-hypothesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-fibril-formation-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-metalloproteinases","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-amyloid-beta-40-abeta-40","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-amyloid-pet-imaging","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-amyloid-pet","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-app-protein","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-aria-imaging","link_type":"mentions","strength":0.5,"evidence":"Entity 'AMYLOID' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-astrocyte-modulation-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-astrocyte-metabolic-modulation-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-astrocyte-neuron-metabolic-coupling-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-eaat2-glutamate-buffer-rescue","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-eeat2-glutamate-buffer-rescue","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-astrocyte-neuron-reprogramming","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-astrocyte-therapeutics-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocyte-precursor-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-senescence-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-reactivity-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-iron-alpha-synuclein-pathology","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-reactivity","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-neuron-metabolic-coupling","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-astrocyte-metabolic-enhancement-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-astrocyte-exosomal-mrna-reference-genes","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-astrocyte-pd-therapy-companies","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-astrocyte-targeted-parkinsons-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-astrocyte-ferritin-iron-metabolism-pd","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-astrocyte-neuron-metabolic-coupling-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-neuroprotection","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROPROTECTION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-biomarker-guided-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-combination-therapy-biomarker-validation","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-biomarker-neuron-entities","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-biomarker-therapeutic-development-nexus","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-biomarker-discovery-framework","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-biomarker-classification-cbs","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-biomarker-overview","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-biomarker-guided-therapy-sequencing-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BIOMARKER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-therapeutics-serotonin-receptor-modulators-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-sert-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-spinal-projection-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-5-ht6-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5ht2a-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5-ht2c-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5-ht1a-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-5-ht7-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5ht1a-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-transporter-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-5-ht5-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5-ht1d-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-neurons-mood","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5-ht1f-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5-ht1b-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5-ht2a-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-5-ht4-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5-ht3-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-serotonin-5-ht1e-receptor-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-serotonin-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-serotonin-signaling-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-serotonin","link_type":"mentions","strength":0.5,"evidence":"Entity 'SEROTONIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-pain-autonomic-symptoms-parkinsonism-nct05748028","link_type":"mentions","strength":0.5,"evidence":"Entity 'PAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-serotonin-pet-pain-pd-nct06008704","link_type":"mentions","strength":0.5,"evidence":"Entity 'PAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-blood-flow-restriction-pd-balance-nct06508801","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-clinical-trials-bfr-balance-pd-nct06508801","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-bbb-penetration-technologies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-blood-brain-barrier-transport-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-blood-brain-barrier-endothelial-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-ptau217-onset-timing-clock","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-breakdown-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier-breakdown-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-based-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-breakdown-disease-driver","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-dysfunction-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier-dysfunction","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-dysfunction-vascular-ci","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier-biology","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-bbb-dysfunction-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-bbb-crossing","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-ptau217-onset-timing-clock","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-microbial-signatures-parkinson","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-ptau-systemic-amyloidosis","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-based-biomarkers-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-blood-biomarkers-atypical-parkinsonism","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-bbb-integrity-cbs","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-blood-brain-barrier-cbs","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-blood-biomarkers-atypical-parkinsonism","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-blood-biomarker-ad-detection","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-blood-brain-barrier-aging-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-blood-biomarker-vs-tau-pet-monitoring","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-events-aaic-2026-biomarker-integration-blood-biomarkers-validation","link_type":"mentions","strength":0.5,"evidence":"Entity 'BLOOD' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-parkin-protein","link_type":"mentions","strength":0.5,"evidence":"Entity 'PARKIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-nlrp3-inflammasome-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NLRP3' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-nrf2-activator-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'NRF2' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-plor","link_type":"mentions","strength":0.5,"evidence":"Entity 'PLOR' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-scrib","link_type":"mentions","strength":0.5,"evidence":"Entity 'SCRIB' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-star","link_type":"mentions","strength":0.5,"evidence":"Entity 'STAR' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-sting","link_type":"mentions","strength":0.5,"evidence":"Entity 'STING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-dysf","link_type":"mentions","strength":0.5,"evidence":"Entity 'DYSF' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-idua","link_type":"mentions","strength":0.5,"evidence":"Entity 'IDUA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-genes-sust","link_type":"mentions","strength":0.5,"evidence":"Entity 'SUST' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-mlcs-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-mitochondria-lysosome-contact-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-mlsm-axis-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mlcs-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitochondria-lysosome-contact-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitochondria-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-mitochondria-lysosome-contact-sites","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-mitochondria","link_type":"mentions","strength":0.5,"evidence":"Entity 'MITOCHONDRIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-hypotheses-stress-granule-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-payload-stress-granule-modulation-therapy","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-stress-granules-rnp","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-stress-granule-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-stress-granule-neuron","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granule-rna-granules","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granules-in-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-response-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granule-dynamics","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granules-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granules","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granule-disease-comparison","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-stress-granule-dysfunction-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-stress-granule-dysfunction-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'STRESS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-circuits-dementia-lewy-bodies-circuit","link_type":"mentions","strength":0.5,"evidence":"Entity 'DEMENTIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-dementia-lewy-bodies-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'DEMENTIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-dementia-lewy-bodies-biomarkers","link_type":"mentions","strength":0.5,"evidence":"Entity 'DEMENTIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-gaps-dementia-lewy-bodies","link_type":"mentions","strength":0.5,"evidence":"Entity 'DEMENTIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-dementia-lewy-bodies-methods","link_type":"mentions","strength":0.5,"evidence":"Entity 'DEMENTIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-dementia-discovery-fund","link_type":"mentions","strength":0.5,"evidence":"Entity 'DEMENTIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-dementia-australia","link_type":"mentions","strength":0.5,"evidence":"Entity 'DEMENTIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-circuits-alzheimer-hippocampal-circuit","link_type":"mentions","strength":0.5,"evidence":"Entity 'ALZHEIMER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-alzheimer-europe","link_type":"mentions","strength":0.5,"evidence":"Entity 'ALZHEIMER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-institutions-alzheimer-indonesia","link_type":"mentions","strength":0.5,"evidence":"Entity 'ALZHEIMER' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-circuits-parkinson-basal-ganglia-circuit","link_type":"mentions","strength":0.5,"evidence":"Entity 'PARKINSON' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-ideas-synapse-resilience-bdnf-glymphatic","link_type":"mentions","strength":0.5,"evidence":"Entity 'SYNAPSE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-synapse-elimination-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'SYNAPSE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-investment-apoptosis-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'APOPTOSIS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-apoptosis-alzheimers-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'APOPTOSIS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-apoptosis","link_type":"mentions","strength":0.5,"evidence":"Entity 'APOPTOSIS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-apoptosis-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'APOPTOSIS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-apoptosis-parkinsons-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'APOPTOSIS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-apoptosis","link_type":"mentions","strength":0.5,"evidence":"Entity 'APOPTOSIS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-of-meyert","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-solitarius","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-solitarius-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-solitarius-cardiovagal","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basal-optic-root","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-spinalis-nervi-trigemini","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cholinergic-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-core-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-caeruleus-subdivision","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-spinalis-v","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-darkschewitsch-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-meyert-basal-nucleus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-prepositus-hypoglossi","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-of-darkschewitsch","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-commissural-nucleus-cuneatus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-solitary-tract","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ambiguus-compacta","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphe-pallidus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-prepositus-hypoglossi-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-fields-of-forel","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphes-obscurus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-solitary-tract-visceral","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-meynert-cholinergic-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-memory","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-parabrachialis-lateralis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-retroventralis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-neurons-lewy-body","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-zona-incerata","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphes-pallidus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-y-accessory-optic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-optic-tract","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-in-parkinsons-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-spinalis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-cuneatus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-accumbens-core-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphé-pallidus-serotonergic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-solitarius-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-diagonal-brocacholinergic-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-brachium-inferior-colliculus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-diagonal-band-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-prepositus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-pretectalis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-reticularis-thalami","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-vertical-limb-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphe-magnus-serotonergic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-gigantocellularis-alpha","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-medium-spiny-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-intercalatus-stamurae","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-solitarius","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-d1-msns-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-diagonal-band-cholinergic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-incertus-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-expanded-v2","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-solitary-tract-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphes-obscurus-expanded-v2","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-shell-gabaergic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-pars-cavernosa","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-shell-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-paragigantocellularis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-optictract","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-vestibularis-superior-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-lateral-olfactory-tract","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ovalis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-diagonal-band-vertical-limb","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-solitarii-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-fimbrialis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cortical","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-incertus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-solitary-tract-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cuneateurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-facial-nucleus-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-reuniens","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-darkschewitsch","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-limitans","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-rhomboid-thalamic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-propositus-hypoglossi-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-parabrachialis-medialis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cortical-projection","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-solitarius-neurod","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-dementia","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ovoidalis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-reuniens-memory","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cholinergic-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-opticus-basalis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-sagulum","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-meynert-cholinergic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-gracilis-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-diagonal-band","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-reward","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-core-learning","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-diagonal-band-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-brachium-superior-colliculus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ambiguus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-diagonal-band-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-ansa-lenticularis-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-lateral-lemniscus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-incertus-nucleus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-reuniens-thalamic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-z","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphe-obscurus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-vertical-limb-diagonal-band","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-shell","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-reticularis-thalami-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-accumbens-shell-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-shell-median-shell-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-retroambiguus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ambiguus-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-posterior-commissure","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-d2-msns-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-pretectal-olivary","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-solitary-tract-nucleus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-neurons-anhedonia","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ovalis-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-koelliker-fuse","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-cholinergic-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ambiguus-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-shell-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ovoidalis-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphe-magnus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-core-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-posterior-commissure-nucleus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphes-magnus-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphespiralis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-core","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphes-magnus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ambiguus-cardiac-control","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-of-da","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-diagonal-band-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-vertical-limb","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-prepositus-hypoglossi","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-meynert","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cholinergic-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ruber","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-tractus-solitarius-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-ellipticus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-of-belzear","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-neurons-ad","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphes-pallidus-expanded","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-circularis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-basalis-meynert-cholinergic","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-field-of-forel-nucleus","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-accumbens-shell-reward","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-gracilis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-raphe-magnus-pain-modulation","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nucleus-pars-cochlearis","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-nucleus-basalis-meynert","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-nucleus-basalis-of-meynert","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-nucleus-accumbens","link_type":"mentions","strength":0.5,"evidence":"Entity 'NUCLEUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-neurodegeneration-parkinson","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dementia-with-lewy-bodies-astrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-argyrophilic-grain-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-hepatic-encephalopathy","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-homeostasis","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-als","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-astrocytes-wilson-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-astrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'ASTROCYTES' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-dentatorubral-pallidoluysian-atrophy-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-wilson-disease-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-neurons-hierarchy","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-normal-pressure-hydrocephalus-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-prion-disease-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-lysosomal-storage-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-spinocerebellar-ataxia-type-3-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-viral-entry-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURONS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-basal-radial-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-neural-crest-derived-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-bergmann-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-ng2-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-muller-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-satellite-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-radial-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-outer-radial-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-nigral-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-enteric-glia","link_type":"mentions","strength":0.5,"evidence":"Entity 'GLIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-spinal-interneurons-motor-neuron-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cerebellar-purkinje-cells-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-cholinergic-neurons-in-lewy-body-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-pedunculopontine-nucleus-neurons-lewy-body-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cerebellar-neurons-creutzfeldt-jakob-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cerebellar-granule-cells-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-ivns1abp-mutation-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cross-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cerebrovascular-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'DISEASE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-hypoxia-sensitive-dopaminergic-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'HYPOXIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-hypoxia-sensitive-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'HYPOXIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-hypoxia-response","link_type":"mentions","strength":0.5,"evidence":"Entity 'HYPOXIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-hypoxia-neuroprotection-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity 'HYPOXIA' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-adrenal-chromaffin-cells","link_type":"mentions","strength":0.5,"evidence":"Entity 'ADRENAL' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-adrenal-chromaffin-cells-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'ADRENAL' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-aging-associated-astrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-aging-oligodendrocytes","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-aging-microglia","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-aging-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-aging-to-ad-switch-trigger","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"mentions","strength":0.5,"evidence":"Entity 'AGING' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-cell-types-cardiac-intrinsic-neurons","link_type":"mentions","strength":0.5,"evidence":"Entity 'CARDIAC' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-cardiac-mibg-scan","link_type":"mentions","strength":0.5,"evidence":"Entity 'CARDIAC' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-hippo-pathway-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'HIPPO' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-hippo-signaling-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'HIPPO' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-hippo-signaling-parkinsons-disease","link_type":"mentions","strength":0.5,"evidence":"Entity 'HIPPO' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-hippo-signaling-4r-tauopathies","link_type":"mentions","strength":0.5,"evidence":"Entity 'HIPPO' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-ad-neuroinflammation-microglia-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbs-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-cbd-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-pd-neuroinflammation","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diagnostics-cbs-psp-neuroinflammation-pet","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEUROINFLAMMATION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-camp-signaling-neurodegeneration","link_type":"mentions","strength":0.5,"evidence":"Entity 'CAMP' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-camp-signaling","link_type":"mentions","strength":0.5,"evidence":"Entity 'CAMP' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-traumatic-brain-injury-neurodegeneration-pathway","link_type":"mentions","strength":0.5,"evidence":"Entity 'TRAUMATIC BRAIN INJURY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-experiments-tbi-alzheimers-mechanism","link_type":"mentions","strength":0.5,"evidence":"Entity 'TRAUMATIC BRAIN INJURY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-tumor-derived-cystatin-c-amyloid-clearance","link_type":"mentions","strength":0.5,"evidence":"Entity 'TUMOR' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-tumor-necrosis-factor-alpha-tnfa","link_type":"mentions","strength":0.5,"evidence":"Entity 'TUMOR' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-tumor-necrosis-factor","link_type":"mentions","strength":0.5,"evidence":"Entity 'TUMOR' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-angiogenesis","link_type":"mentions","strength":0.5,"evidence":"Entity 'ANGIOGENESIS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-mechanisms-actin-cytoskeleton-dynamics","link_type":"mentions","strength":0.5,"evidence":"Entity 'ACTIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-memory-prosthetic-bci","link_type":"mentions","strength":0.5,"evidence":"Entity 'MEMORY' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-technologies-spect","link_type":"mentions","strength":0.5,"evidence":"Entity 'SPECT' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-biomarkers-neuron-specific-enolase-nse","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURON' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-neuron-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'NEURON' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-nf-kb","link_type":"mentions","strength":0.5,"evidence":"Entity 'NF-KB' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-entities-acetylcholine","link_type":"mentions","strength":0.5,"evidence":"Entity 'ACETYLCHOLINE' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-companies-cognition-therapeutics","link_type":"mentions","strength":0.5,"evidence":"Entity 'COGNITION' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-hippocampus","link_type":"mentions","strength":0.5,"evidence":"Entity 'HIPPOCAMPUS' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-brain-regions-basal-forebrain","link_type":"mentions","strength":0.5,"evidence":"Entity 'BASAL FOREBRAIN' mentioned in hypothesis description/evidence"},{"source_artifact_id":"wiki-diseases-nbia","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mpan","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-india-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pla2g6-associated-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-bpan","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-japan-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-european-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-economic-burden-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-global-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-neurodegeneration-impact-measures","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pantothenate-kinase-associated-neurodegeneration-pkan","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-china-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-disease-progression","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-sleep-disorders-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pkan","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mitochondrial-dysfunction-neurodegeneration-comparison","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-familial-vs-sporadic-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mitochondrial-neurodegeneration-comparison","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-daly-methodology-neurodegeneration","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-us-neurodegeneration-epidemiology","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-manganism","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-clinical-trials-beacon-study-nct03860857","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-clinical-trials-olfactory-mucosa-early-neurodegeneration-nct06846658","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-clinical-trials-gut-brain-axis-neurodegeneration-nct05934188","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-clinical-trials-swedish-biofinder-2-psp-nct03174938","link_type":"related","strength":0.6,"evidence":"Disease page related to hypothesis disease: neurodegeneration"},{"source_artifact_id":"wiki-proteins","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-clinical-trials-varenicline-falls-pd-nct06679374","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-proteins-ric3-protein","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-proteins-chrna2-protein","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-genes-chrnb1","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-genes-chat","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-genes-chrnb3","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-genes-ddc","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-cell-types-paratenial-nucleus","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-cell-types-laterodorsal-tegmental-cholinergic","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-cell-types-cholinergic-neurons-neurodegeneration","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-cell-types-striatal-cholinergic-interneurons","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"wiki-genes-ace","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ACE → CHRNA7"},{"source_artifact_id":"wiki-proteins-akt1","link_type":"related","strength":0.55,"evidence":"Shared KG edge: AKT1 → CHRNA7"},{"source_artifact_id":"wiki-clinical-trials-a4-study","link_type":"related","strength":0.5,"evidence":"Wiki title word 'ANTI' found in hypothesis pathway"},{"source_artifact_id":"wiki-cell-types-hippocampal-ca3-neurons-alzheimer","link_type":"related","strength":0.5,"evidence":"KG edge: cell-types-hippocampal-ca3-neurons-alzheimer --associated_with--> CHRNA7 (hypothesis target)"},{"source_artifact_id":"wiki-researchers-alois-alzheimer","link_type":"related","strength":0.5,"evidence":"KG edge: researchers-alois-alzheimer --associated_with--> CHRNA7 (hypothesis target)"},{"source_artifact_id":"wiki-proteins-amyloid-beta","link_type":"related","strength":0.5,"evidence":"KG edge: proteins-amyloid-beta --activates--> CHRNA7 (hypothesis target)"},{"source_artifact_id":"wiki-mechanisms-pink1-parkin-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ftd-tdp43-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tau-seeding-propagation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-atp13a2-lysosomal-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dat-dysfunction-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-igf-1-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dopaminergic-neuron-vulnerability","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-trace-amine-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ceramide-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mesolimbic-dopamine-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-alpers-huttenlocher-syndrome-mtdna-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-reactive-oxygen-species","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gaucher-disease-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-autosis-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nlrp3-inflammasome-ad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gba-glucocerebrosidase-endolysosomal-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-quality-control-network-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ampk-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mapk-erk-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-park2-parkin-ubiquitin-ligase-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hypoxia-response","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ras-mapk-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nfkb-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-huntingtons-disease-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-astrocyte-senescence-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nurr1-nr4a2-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-intrinsic-apoptosis-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-sporadic-alzheimers-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gdnf-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-vps35-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-htt-transcriptional-dysregulation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-zinc-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-brain-reserve-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tdp43-rna-granule-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hippo-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-oligodendrocyte-dysfunction-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-wnt-beta-catenin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-fa2h-associated-neurodegeneration-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-protein-o-glcna-cylation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-frontotemporal-dementia-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ad-neuroinflammation-microglia-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-protein-kinase-c-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pkr-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-synaptic-loss-ad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-lrrk2-pathway-parkinson-disease","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-apoe-lipid-metabolism-alzheimers","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neurovascular-ad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nrf2-oxidative-stress","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-noradrenergic-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mitophagy-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glucocorticoid-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-oligodendrocyte-dysfunction-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-lrrk2-kinase-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-s100-protein-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tgf-beta-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pallido-thalamocortical-motor-pathway-pd","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nrf2-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-vascular-dementia-mechanism-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hedgehog-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-endolysosomal-pathway-alzheimers","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-braak-staging-tau-propagation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-il-1-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-synuclein-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cortisol-tau-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-prion-disease-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pkan-neurodegeneration-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-cellular-uptake-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-progesterone-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-vagus-nerve-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-multiple-system-atrophy-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-synaptic-dysfunction-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-autophagy-lysosomal-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mtor-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neuroimmune-interface","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-bace1-amyloidogenic-cleavage-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cbs-autophagy-lysosomal-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dementia-lewy-bodies-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-microglial-priming-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-jak-stat-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-alpha-synuclein-propagation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-down-syndrome-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glycosaminoglycan-metabolism","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tau-pathology-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hippo-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ghrelin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-camkii-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-als-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-synaptic-loss-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-p-body-processing-bodies-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-traumatic-brain-injury-neurodegeneration-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dopamine-metabolism","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-er-stress-unfolded-protein-response","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cerebral-amyloid-angiopathy-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-lrrk2-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-calcium-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-retinal-degeneration-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dysfunction-ad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hexosamine-biosynthetic-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-endosomal-lysosomal-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-endothelin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-brain-volume-changes-ad","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ppar-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-s1p-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-trem2-amyloid-clearance-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gba-glucocerebrosidase-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pallido-thalamocortical-motor-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-trans-synaptic-spread-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-rage-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pyroptosis-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-bdnf-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-notch-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-alpha-synuclein-aggregation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-trem2-cytokine-regulation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tgf-beta-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-endosomal-trafficking","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pink1-parkin-mitophagy-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-synaptic-vesicle-cycling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cgmp-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nlrp3-inflammasome-activation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cgas-sting-cytosolic-dna-sensing-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-slit-robo-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-protein-oligomerization-toxicity-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dj1-oxidative-stress-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-heat-shock-protein-response-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-amyloid-cascade-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neuroinflammation-microglia-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-notch-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-normal-pressure-hydrocephalus-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gdnf-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-brain-region-therapeutic-targeting-index","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ftd-tau-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-leptin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-vps35-retromer-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cntf-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-trem2-microglial-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-androgen-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-fgf-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hippo-signaling-parkinsons-disease","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-focal-adhesion-kinase-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-protein-sumoylation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-oxidative-stress-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-peroxisome-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ferroptosis-neurodegeneration-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-adiponectin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-apoptosis","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-retrograde-transport-endosomal-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-rem-sleep-behavior-disorder-neurodegeneration-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-erythropoietin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-amyloid-cascade","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ferroptosis-ad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-psp-central-vestibular-pathway-vulnerability","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-vegf-angiogenesis-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-histamine-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-sirtuin-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nlrp3-inflammasome-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-necroptosis","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-melatonin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-semaphorin-plexin-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neuroinflammation-ad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dyrk1a-tau-phosphorylation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tgf-beta-bmp-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ferroptosis-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-orexin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-foxo-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tau-phosphorylation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cerebellar-degeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nf-kappa-b-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glymphatic-system-dysfunction","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-lipophagy-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-p75ntr-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dopamine-biosynthesis-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nad-metabolism-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-huntingtin-proteolysis-cleavage-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-kynurenine-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-serotonin-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-p70s6k-mtorc1-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-bdnf-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-somatostatin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cbd-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ephrin-ephr-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-peroxisome-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-synaptic-spine-degradation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-kynurenine-4r-tauopathies","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-autophagic-cell-death-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ceramide-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-uchl1-park5-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-vascular-cognitive-impairment-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hydrogen-sulfide-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-membrane-trafficking-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tlr-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ubiquitin-proteasome-ad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-brain-endothelial-cell-dysfunction-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-4r-tauopathies-brain-region-vulnerability","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-chemokine-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-integrin-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pd-lrrk2-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mitochondrial-dynamics-fusion-fission","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-wnt-beta-catenin-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-excitotoxicity-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dopamine-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-stroke-neurodegeneration-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-calcium-excitotoxicity-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-oligomerization-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pd-synaptic-vesicle-trafficking-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-rna-toxicity","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neuroinflammation-mitochondria-crosstalk","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-calcineurin-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-jnk-p38-mapk-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-anti-amyloid-therapeutics","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gdnf-neurotrophic-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-er-stress-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mark-tau-phosphorylation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-vitamin-d-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-jak-stat-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-lewy-body-formation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gba-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-multiple-sclerosis-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mitophagy-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mitophagy-receptor-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-serotonin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-white-matter-lesion-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-transcription-regulation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-golgi-apparatus-dysfunction","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-lrrk2-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mutant-huntingtin-aggregation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-er-stress-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neuronal-network-dysfunction-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-camp-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nrf2-keap1-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neurotrophic-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-als-sod1-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-brain-insulin-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-metabolic-dysfunction-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gdnf-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-ephrin-ephr-receptor-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mirna-regulation-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nt-3-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cgas-sting-ad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pi3k-akt-mtor-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-proteasomal-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mapk-erk-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-netrin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-notch-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gaba-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-niemann-pick-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glucocorticoid-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-lrrk2-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-infantile-neuroaxonal-dystrophy-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tanycytes-tau-clearance","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glutamate-excitotoxicity-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-msa-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-sestrin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-autophagy-lysosomal-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-polyamine-metabolism-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-insulin-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-angiogenesis","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-fabry-disease-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-als-c9orf72-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cxcl12-cxcr4-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hydrogen-peroxide-metabolism","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-wnt-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nt-4-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-thyroid-hormone-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tfeb-autophagy-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-yap-taz-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-p53-parkinson-disease","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-autophagy-lysosome-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tnf-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cerebral-ischemia-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-natriuretic-peptide-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-huntington-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gabaergic-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-autophagy-lysosome-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pd-neuroinflammation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cytoskeletal-dynamics-axonal-transport","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-akt-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neuropeptide-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dj1-park7-neuroprotection-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-park7-dj1-neuroprotection-pd-causal-chain","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-brain-age-gap-amyloid-ad","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cgas-sting-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cell-cycle-re-entry-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-insulin-signaling-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glutathione-metabolism","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-wilsons-disease-copper-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-peroxisome-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-rna-metabolism-dysregulation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-microglial-senescence-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-pp2a-tau-phosphatase-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-alpha-synuclein-aggregation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-il-6-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-app-amyloid-pathway-alzheimers","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nlrp3-inflammasome-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gdf-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-gsk3-beta-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-sting-casm-gabarap-lrrk2-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-synaptic-plasticity","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-viral-involvement-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-lysosomal-storage-disorders-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-synaptic-vesicle-trafficking-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-hsp70-hsp90-chaperone-pathway-parkinsons","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-astrocyte-neuron-metabolic-coupling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-amyloid-beta-fibril-formation-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-atp13a2-park9-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-nfkb-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-complement-system-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dna-damage-response","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-protein-synthesis","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cgas-sting-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dopamine-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-mtor-signaling-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-sphingolipid-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-sirt1-alzheimer-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tyrobp-dap12-microglia-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-dlb-autonomic-dysfunction-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-otulin-tau-regulation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-oligodendrocyte-neuron-metabolic-support","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-neuroimmune-checkpoint-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glutamatergic-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-necroptosis-pathway-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-c9orf72-hexanucleotide-repeat-expansion-als-ftd","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-als-superoxide-dismutase-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-circadian-clock-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-trem2-microglia-pathway-alzheimers","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-bbb-dysfunction-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glp-1-signaling-neurodegeneration","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-cgas-sting-autophagy","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-proteostasis-erad-pathway","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-fus-proteinopathy-pathway-als","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-tau-seeding-propagation","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-glutamate-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-norepinephrine-signaling","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-mechanisms-autophagy-lysosomal-cbs","link_type":"related","strength":0.65,"evidence":"Pathway page related to hypothesis pathway: Vagal cholinergic anti-inflammatory pathway (α7nAChR)"},{"source_artifact_id":"wiki-cell-types-parabrachial-nucleus-gustatory","link_type":"related","strength":0.55,"evidence":"Cell type parabrachial-nucleus-gustatory mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-supraoptic-vasopressin-neurons-neurodegeneration","link_type":"related","strength":0.55,"evidence":"Cell type Supraoptic Vasopressin Neurons Neurodegeneration mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-spinal-cord-interneurons-chronic-pain","link_type":"related","strength":0.55,"evidence":"Cell type spinal-cord-interneurons-chronic-pain mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-hypothalamic-melanocortin-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Hypothalamic Melanocortin Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-hippocampal-ca3-pyramidal-neurons-parkinsons","link_type":"related","strength":0.55,"evidence":"Cell type hippocampal-ca3-pyramidal-neurons-parkinsons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-psd95-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Psd95 Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-subicular-neurons","link_type":"related","strength":0.55,"evidence":"Cell type subicular-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-spinothalamic-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Spinothalamic Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-cannabinoid-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Cannabinoid Receptor Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-peripeduncular-nucleus","link_type":"related","strength":0.55,"evidence":"Cell type peripeduncular-nucleus mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-adenosine-a3-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Adenosine A3 Receptor Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-layer-3-neurons","link_type":"related","strength":0.55,"evidence":"Cell type layer-3-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-claustrum-in-alzheimers-disease","link_type":"related","strength":0.55,"evidence":"Cell type Claustrum-in-Alzheimers-Disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-dopa-decarboxylase-neurons","link_type":"related","strength":0.55,"evidence":"Cell type dopa-decarboxylase-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-ginzburg-nerve-endings","link_type":"related","strength":0.55,"evidence":"Cell type ginzburg-nerve-endings mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-vasopressin-v1a-neurons","link_type":"related","strength":0.55,"evidence":"Cell type vasopressin-v1a-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-medium-spiny-neurons-huntington-disease","link_type":"related","strength":0.55,"evidence":"Cell type medium-spiny-neurons-huntington-disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-acc-chronic-pain","link_type":"related","strength":0.55,"evidence":"Cell type acc-chronic-pain mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-pituitary-somatotrophs-neurodegeneration","link_type":"related","strength":0.55,"evidence":"Cell type Pituitary Somatotrophs Neurodegeneration mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-interpeduncular-nucleus-in-parkinsons-disease","link_type":"related","strength":0.55,"evidence":"Cell type Interpeduncular-Nucleus-in-Parkinsons-Disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-histamine-h3-heteroreceptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type histamine-h3-heteroreceptor-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-myelin-forming-cells","link_type":"related","strength":0.55,"evidence":"Cell type myelin-forming-cells mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-glutamate-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Glutamate Receptor Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-dopamine-d1-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type dopamine-d1-receptor-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-blood-brain-barrier-endothelial-cells","link_type":"related","strength":0.55,"evidence":"Cell type blood-brain-barrier-endothelial-cells mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-catecholaminergic-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Catecholaminergic Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-arterial-endothelial-cells-brain","link_type":"related","strength":0.55,"evidence":"Cell type arterial-endothelial-cells-brain mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-voltage-gated-calcium-channel-neurons","link_type":"related","strength":0.55,"evidence":"Cell type voltage-gated-calcium-channel-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-choroid-plexus-in-alzheimers-disease","link_type":"related","strength":0.55,"evidence":"Cell type Choroid-Plexus-in-Alzheimers-Disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-retinal-amacrine-cells-parkinsons-disease","link_type":"related","strength":0.55,"evidence":"Cell type retinal-amacrine-cells-parkinsons-disease mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-sigma-1-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type sigma-1-receptor-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-serotonergic-raphe-neurons","link_type":"related","strength":0.55,"evidence":"Cell type serotonergic-raphe-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-adult-neural-stem-cells","link_type":"related","strength":0.55,"evidence":"Cell type adult-neural-stem-cells mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-npy-y1-receptor-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Npy Y1 Receptor Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-deep-cerebellar-nuclei-in-ataxia","link_type":"related","strength":0.55,"evidence":"Cell type Deep-Cerebellar-Nuclei-in-Ataxia mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-nucleus-incertus-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Nucleus Incertus Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-circadian-neurons-in-neurodegeneration","link_type":"related","strength":0.55,"evidence":"Cell type Circadian-Neurons-in-Neurodegeneration mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-nlrp3-inflammasome-activated-microglia","link_type":"related","strength":0.55,"evidence":"Cell type nlrp3-inflammasome-activated-microglia mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-enteric-nervous-system-expanded","link_type":"related","strength":0.55,"evidence":"Cell type enteric-nervous-system-expanded mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-tyrosine-hydroxylase-th-neurons","link_type":"related","strength":0.55,"evidence":"Cell type Tyrosine Hydroxylase Th Neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-pontine-nucleus-neurons","link_type":"related","strength":0.55,"evidence":"Cell type pontine-nucleus-neurons mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-cerebellar-granule-cells","link_type":"related","strength":0.55,"evidence":"Cell type Cerebellar Granule Cells mentioned in hypothesis"},{"source_artifact_id":"wiki-cell-types-interpeduncular-nucleus","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene CHRNA7"},{"source_artifact_id":"wiki-cell-types-hippocampal-olk-cells","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene CHRNA7"},{"source_artifact_id":"wiki-mechanisms-ad-ion-channel-dysfunction","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene CHRNA7"},{"source_artifact_id":"wiki-entities-donepezil","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene CHRNA7"},{"source_artifact_id":"wiki-cell-types-brain-vascular-endothelial-cells","link_type":"related","strength":0.55,"evidence":"Cell type Brain Vascular Endothelial Cells in hypothesis title"},{"source_artifact_id":"wiki-cell-types-brain-organoids","link_type":"related","strength":0.55,"evidence":"Cell type Brain Organoid Neurons in hypothesis title"},{"source_artifact_id":"wiki-cell-types-capillary-endothelial-cells-brain","link_type":"related","strength":0.55,"evidence":"Cell type Brain Capillary Endothelial Cells in hypothesis title"},{"source_artifact_id":"wiki-cell-types-endothelial-cells-brain","link_type":"related","strength":0.55,"evidence":"Cell type Brain Endothelial Cells in hypothesis title"},{"source_artifact_id":"wiki-cell-types-endothelial-cells-neurodegeneration","link_type":"related","strength":0.55,"evidence":"Cell type Brain Endothelial Cells in Neurodegeneration in hypothesis title"},{"source_artifact_id":"wiki-cell-types-venous-endothelial-cells-brain","link_type":"related","strength":0.55,"evidence":"Cell type Brain Venous Endothelial Cells in hypothesis title"},{"source_artifact_id":"wiki-cell-types-pericytes-brain","link_type":"related","strength":0.55,"evidence":"Cell type Brain Pericytes in hypothesis title"},{"source_artifact_id":"wiki-cell-types-brain-endothelial-cells","link_type":"related","strength":0.55,"evidence":"Cell type Brain Endothelial Cells in hypothesis title"},{"source_artifact_id":"wiki-cell-types-brain-pericytes","link_type":"related","strength":0.55,"evidence":"Cell type Brain Pericytes in Neurodegeneration in hypothesis title"},{"source_artifact_id":"wiki-cell-types-ependymal-cells-brain","link_type":"related","strength":0.55,"evidence":"Cell type Brain Ependymal Cells in hypothesis title"},{"source_artifact_id":"wiki-cell-types-brain-pericytes-neurodegeneration","link_type":"related","strength":0.55,"evidence":"Cell type Brain Pericytes in Neurodegeneration in hypothesis title"},{"source_artifact_id":"wiki-diseases-mitochondrial-dysfunction-neurodegeneration-comparison","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-china-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-familial-vs-sporadic-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-global-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-bpan","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-manganism","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-neurodegeneration-impact-measures","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-economic-burden-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-european-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-us-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-nbia","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-india-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pkan","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mpan","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-disease-progression","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-daly-methodology-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pantothenate-kinase-associated-neurodegeneration-pkan","link_type":"mentions","strength":0.6,"evidence":"Disease: neurodegeneration"},{"source_artifact_id":"wiki-diseases-pla2g6-associated-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-cell-types-dopaminergic-neurons","link_type":"mentions","strength":0.65,"evidence":"Title match: Dopaminergic Neurons"},{"source_artifact_id":"wiki-mechanisms-alpha-synuclein-pathology","link_type":"mentions","strength":0.65,"evidence":"Title match: Alpha-Synuclein Pathology"},{"source_artifact_id":"wiki-cell-types-vagal-afferent-neurons","link_type":"mentions","strength":0.65,"evidence":"Title match: Vagal Afferent Neurons"},{"source_artifact_id":"wiki-brain-regions-brainstem","link_type":"mentions","strength":0.65,"evidence":"Title match: Brainstem"},{"source_artifact_id":"wiki-mechanisms-blood-brain-barrier","link_type":"mentions","strength":0.65,"evidence":"Title match: Blood-Brain Barrier"},{"source_artifact_id":"wiki-diseases-stroke","link_type":"mentions","strength":0.65,"evidence":"Title match: Stroke"},{"source_artifact_id":"wiki-clinical-trials","link_type":"mentions","strength":0.65,"evidence":"Title match: Clinical Trials"},{"source_artifact_id":"wiki-cell-types-blood-brain-barrier","link_type":"mentions","strength":0.65,"evidence":"Title match: Blood-Brain Barrier"},{"source_artifact_id":"wiki-brain-regions-dorsal-motor-nucleus-vagus","link_type":"mentions","strength":0.65,"evidence":"Title match: Dorsal Motor Nucleus of the Vagus"},{"source_artifact_id":"wiki-entities-microbiome","link_type":"mentions","strength":0.65,"evidence":"Title match: Microbiome"},{"source_artifact_id":"wiki-cell-types-dorsal-motor-nucleus-vagus","link_type":"mentions","strength":0.65,"evidence":"Title match: Dorsal Motor Nucleus of the Vagus"},{"source_artifact_id":"wiki-cell-types-enteric-neurons","link_type":"mentions","strength":0.65,"evidence":"Title match: Enteric Neurons"},{"source_artifact_id":"wiki-diseases-parkinsons-disease","link_type":"mentions","strength":0.65,"evidence":"Title match: Parkinson's Disease"},{"source_artifact_id":"wiki-diseases-alzheimers-disease","link_type":"mentions","strength":0.65,"evidence":"Title match: Alzheimer's Disease"},{"source_artifact_id":"wiki-entities-nlrp3-inflammasome","link_type":"mentions","strength":0.65,"evidence":"Title match: NLRP3 Inflammasome"},{"source_artifact_id":"wiki-brain-regions","link_type":"mentions","strength":0.65,"evidence":"Title match: Brain Regions"},{"source_artifact_id":"wiki-cell-types-endothelial-cells","link_type":"mentions","strength":0.65,"evidence":"Title match: Endothelial Cells"},{"source_artifact_id":"wiki-diagnostics-neuroimaging","link_type":"mentions","strength":0.65,"evidence":"Title match: neuroimaging"},{"source_artifact_id":"wiki-diseases-vascular-dementia","link_type":"mentions","strength":0.65,"evidence":"Title match: Vascular Dementia"},{"source_artifact_id":"wiki-cell-types-dorsal-motor-vagus","link_type":"mentions","strength":0.65,"evidence":"Title match: Dorsal Motor Nucleus of the Vagus"},{"source_artifact_id":"wiki-diseases-japan-neurodegeneration-epidemiology","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-proteins-alpha-synuclein","link_type":"mentions","strength":0.65,"evidence":"Title match: alpha-synuclein"},{"source_artifact_id":"wiki-diseases-sleep-disorders-neurodegeneration","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"wiki-diseases-mitochondrial-neurodegeneration-comparison","link_type":"mentions","strength":0.6,"evidence":"Disease match: neurodegeneration"},{"source_artifact_id":"open_question-18b8ff5a-2a35-41c7-851f-2500f9b93ae7","link_type":"candidate_answer","strength":0.9,"evidence":"{\"confidence\": 0.9, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"}],"current_artifact_id":"hypothesis-h-a4e259e0","is_canonical":true,"supersede_chain":["hypothesis-h-a4e259e0"]}