{"artifact":{"id":"landscape-synthetic-biology-lineage-tracing-20260425170559","artifact_type":"landscape_analysis","entity_ids":null,"title":"Landscape Analysis: 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of off-target and on-target scoring algorithms and integration into the guide RNA selecti","journal":"Genome biology"},{"pmid":"https://openalex.org/W3195285310","year":2021,"title":"Genome-wide association studies","journal":"Nature Reviews Methods Primers"},{"pmid":"https://openalex.org/W2203265148","year":2016,"title":"A genome-wide resource for the analysis of protein localisation in Drosophila","journal":"eLife"},{"pmid":"10.1186/s13059-019-1725-0","year":2019,"title":"Collateral damage: benchmarking off-target effects in genome editing","journal":"Genome Biology"},{"pmid":"10.1089/crispr.2022.0042","year":2022,"title":"JACKIE: Fast Enumeration of Genome-Wide Single- and Multicopy CRISPR Target Sites and Their Off-Targ","journal":"The CRISPR Journal"}],"cell_perturb_seq":[{"pmid":"https://openalex.org/W2561754210","year":2016,"title":"Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled 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base editors","journal":"Nature"},{"pmid":"10.3390/ijms21176240","year":2020,"title":"CRISPR-Cas9 DNA Base-Editing and Prime-Editing","journal":"International Journal of Molecular Sciences"},{"pmid":"10.1021/acs.biochem.9b00573","year":2019,"title":"Off-Target Editing by CRISPR-Guided DNA Base Editors","journal":"Biochemistry"},{"pmid":"10.1089/crispr.2019.0017","year":2019,"title":"BEAT: A Python Program to Quantify Base Editing from Sanger Sequencing","journal":"The CRISPR Journal"}],"cell_crispr_screen":[{"pmid":"https://openalex.org/W2885096157","year":2018,"title":"Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function","journal":"Cell"},{"pmid":"35750052","year":2022,"title":"Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T c","journal":"Cancer Cell"}],"cell_prime_editing":[{"pmid":"10.1089/crispr.2021.0080","year":2022,"title":"Genomic and Transcriptomic Analyses of Prime Editing Guide RNA–Independent Off-Target Effects by Pri","journal":"The CRISPR Journal"},{"pmid":"10.1007/978-981-19-0600-8_9","year":2022,"title":"Plant Precise Genome Editing by Prime Editing","journal":"Genome Editing Technologies for Crop Improvement"},{"pmid":"36251123","year":2023,"title":"Prime Editing: An Emerging Tool in Cancer Treatment.","journal":"Mol Biotechnol"}],"cell_synthetic_bio":[{"pmid":"10.1038/nature19841","year":2016,"title":"Synchronous long-term oscillations in a synthetic gene circuit","journal":"Nature"},{"pmid":"10.1371/journal.pcbi.1002480","year":2012,"title":"Mapping the Environmental Fitness Landscape of a Synthetic Gene Circuit","journal":"PLoS Computational Biology"},{"pmid":"10.1038/ncomms3825","year":2013,"title":"A closed-loop synthetic gene circuit for the treatment of diet-induced obesity in mice","journal":"Nature Communications"},{"pmid":"10.1038/s41564-017-0022-5","year":2017,"title":"An integrative circuit–host modelling framework for predicting synthetic gene network behaviours","journal":"Nature Microbiology"},{"pmid":"10.1093/bioinformatics/btn330","year":2008,"title":"Computational design of synthetic gene circuits with composable parts","journal":"Bioinformatics"}],"cell_crispr_lineage":[{"pmid":"https://openalex.org/W2077659966","year":2013,"title":"High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells","journal":"Nature Biotechnology"},{"pmid":"https://openalex.org/W3017334101","year":2020,"title":"CRISPR–Cas12-based detection of SARS-CoV-2","journal":"Nature Biotechnology"},{"pmid":"https://openalex.org/W2995081665","year":2019,"title":"Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants","journal":"Nature Reviews Microbiology"},{"pmid":"https://openalex.org/W2115603949","year":2014,"title":"Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 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