{"artifact":{"id":"open_question-587028fd-0a1e-4128-9aa8-12103c709890","artifact_type":"open_question","entity_ids":"[\"genes\"]","title":"Can transport be enhanced in aged neurons?","quality_score":0.5,"created_by":"backfill_open_questions","provenance_chain":"[]","content_hash":"2263ebcd286a7fe1dbb35693f1a5655830e281e50c83671e372f75637774729a","metadata":{"status":"open","_origin":{"url":null,"type":"internal","tracked_at":"2026-04-26T03:29:44.608934"},"field_tag":"genes","source_id":"genes-kif21b","sub_field":"kif21b","source_kind":"wiki","question_hash":"160ee4cd991df1d76ed0d6fcddb84b69434a56f49cf26d8e5c82cbc9c68b690b","question_text":"Can transport be enhanced in aged neurons?","importance_elo":1500,"_schema_version":1,"evidence_summary":"Extracted from wiki page genes-kif21b","evidence_xref_at":"2026-04-27T12:20:42.825285+00:00","tractability_score":0.5,"potential_impact_score":0.5},"created_at":"2026-04-25T20:29:44.609053-07:00","updated_at":"2026-04-25T20:29:44.609053-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-25T20:29:44.609053-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":null,"contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"27c8b5d4-d990-403b-8da7-a9ae6669b35a","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"backfill_open_questions"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"wiki-genes-kif21b","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"target_artifact_id":"hypothesis-h-969bd8e0","link_type":"candidate_answer","strength":0.78,"evidence":"{\"confidence\": 0.78, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"hypothesis-h-8196b893","link_type":"candidate_answer","strength":0.82,"evidence":"{\"confidence\": 0.82, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"hypothesis-h-d78123d1","link_type":"candidate_answer","strength":0.81,"evidence":"{\"confidence\": 0.81, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"hypothesis-h-6ce4884a","link_type":"candidate_answer","strength":0.88,"evidence":"{\"confidence\": 0.88, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"hypothesis-h-91bdb9ad","link_type":"candidate_answer","strength":0.88,"evidence":"{\"confidence\": 0.88, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"hypothesis-h-fdaae8d9","link_type":"bears_on_question","strength":0.52,"evidence":"{\"confidence\": 0.52, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"experiment-exp-wiki-experiments-selective-neuronal-vulnerability-aging","link_type":"bears_on_question","strength":0.58,"evidence":"{\"confidence\": 0.58, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"experiment-exp-debate-d34987f83486","link_type":"discriminating_experiment","strength":0.78,"evidence":"{\"confidence\": 0.78, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"experiment-exp-debate-c6e583083862","link_type":"discriminating_experiment","strength":0.78,"evidence":"{\"confidence\": 0.78, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"experiment-exp-debate-775eba06a96a","link_type":"discriminating_experiment","strength":0.71,"evidence":"{\"confidence\": 0.71, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"},{"target_artifact_id":"experiment-exp-wiki-experiments-blood-brain-barrier-aging-neurodegeneration","link_type":"bears_on_question","strength":0.45,"evidence":"{\"confidence\": 0.45, \"judge_persona\": \"domain-expert\", \"model\": \"all-MiniLM-L6-v2\"}"}],"incoming_links":[],"current_artifact_id":"open_question-587028fd-0a1e-4128-9aa8-12103c709890","is_canonical":true,"supersede_chain":["open_question-587028fd-0a1e-4128-9aa8-12103c709890"]}