{"artifact":{"id":"paper-fig-22ece900-f8a9-483b-b7ad-9b8d9b45223a-10","artifact_type":"paper_figure","entity_ids":"[]","title":"Fig. 10: DAPK1 inhibition ameliorates emotional and cognitive impairments in a mouse mode...","quality_score":0.5,"created_by":"paper_figures_pipeline","provenance_chain":"[{\"source\": \"paper\", \"paper_id\": \"22ece900-f8a9-483b-b7ad-9b8d9b45223a\", \"relation\": \"extracted_from\"}]","content_hash":"f1a67f511196328af1852be6626a03b9e2ebfae9c558ae2a40aad856b45ce574","metadata":{"doi":"10.1186/s13024-025-00911-3","pmcid":"PMC12639696","_origin":{"url":"https://www.ebi.ac.uk/europepmc/articles/PMC12639696/bin/13024_2025_911_Fig10_HTML.jpg","type":"external","tracked_at":"2026-04-22T22:53:20.577947"},"caption":"DAPK1 inhibition ameliorates emotional and cognitive impairments in a mouse model of tauopathy. ( A-B)  The Y-maze test was applied to evaluate the short-term memory ability in mice treated with or without C6. The number of NA entry and the percentage of time spent in NA for each group are presented.  n  = 9–11 mice/group.  (C-F)  The open field test (OFT) was employed to analyze the anxiety-like behavior in mice treated with or without C6. Representative movement trajectories ( C ) for each group are shown. The blue square indicates the center area in OFT. The total ambulatory distance ( D ), the percentage of time spent ( E ) and distance traveled ( F ) in the center area are presented.  n  = 10–12 mice/group.  (G-H)  A novel object recognition (NOR) test ( G ) was performed to evaluate the preference toward novel object ( H ) in mice treated with or without C6.  n  = 10–12 mice/group.  (I-M)  Mice were subjected to the MWM test to assess spatial learning and memory abilities. The me","paper_id":"22ece900-f8a9-483b-b7ad-9b8d9b45223a","image_url":"https://www.ebi.ac.uk/europepmc/articles/PMC12639696/bin/13024_2025_911_Fig10_HTML.jpg","image_path":"","description":"","figure_label":"Fig. 10","figure_number":10,"_schema_version":1,"source_strategy":"pmc_api","entities_mentioned":""},"created_at":"2026-04-22T15:53:20.578077-07:00","updated_at":"2026-04-22T15:53:20.578077-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"external","origin_url":"https://www.ebi.ac.uk/europepmc/articles/PMC12639696/bin/13024_2025_911_Fig10_HTML.jpg","lifecycle_changed_at":"2026-04-22T15:53:20.578077-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":null,"contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"eea72f8b-29dd-4982-9e5a-108f70a42904","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"paper_figures_pipeline"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[],"incoming_links":[],"current_artifact_id":"paper-fig-22ece900-f8a9-483b-b7ad-9b8d9b45223a-10","is_canonical":true,"supersede_chain":["paper-fig-22ece900-f8a9-483b-b7ad-9b8d9b45223a-10"]}