{"artifact":{"id":"paper-fig-32155866-1","artifact_type":"paper_figure","entity_ids":"[]","title":"Figure 1: A simplified scheme of the pathophysiological connection of diabetes mellitus an...","quality_score":0.95,"created_by":"paper_figures_pipeline","provenance_chain":"[{\"source\": \"paper\", \"pmid\": \"32155866\", \"relation\": \"extracted_from\"}]","content_hash":"8680ddd357a06cdabe2956a6d60b18ad8d0339a14eb4946d079b79076e55f218","metadata":{"doi":"","pmid":"32155866","pmcid":"PMC7084712","_origin":{"url":"https://www.ebi.ac.uk/europepmc/articles/PMC7084712/bin/ijms-21-01835-g001.jpg","type":"external","tracked_at":"2026-04-10T11:53:11.255517"},"caption":"A simplified scheme of the pathophysiological connection of diabetes mellitus and atherosclerosis. Dyslipidemia, hyperglycemia, and insulin resistance result in a spectrum of physiological changes, including the formation of atherogenic low-density lipoprotein (LDL), advanced glycation end products (AGE), and activation of pro-inflammatory signaling that impact different cell types of the arterial wall, resulting in atherosclerotic lesion development. SMC, smooth muscular cells.","image_url":"https://www.ebi.ac.uk/europepmc/articles/PMC7084712/bin/ijms-21-01835-g001.jpg","image_path":"","description":"","figure_label":"Figure 1","figure_number":1,"_schema_version":1,"source_strategy":"pmc_api","entities_mentioned":""},"created_at":"2026-04-10T04:53:11-07:00","updated_at":"2026-04-19T02:47:45.775518-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"external","origin_url":"https://www.ebi.ac.uk/europepmc/articles/PMC7084712/bin/ijms-21-01835-g001.jpg","lifecycle_changed_at":"2026-04-10T04:53:11-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"d0dbe929-fd2c-4971-8e60-88287c40e415","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"paper_figures_pipeline"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[],"incoming_links":[],"current_artifact_id":"paper-fig-32155866-1","is_canonical":true,"supersede_chain":["paper-fig-32155866-1"]}